DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions:   

Frequency Defined  

>10%  

Diarrhea (16%)  

Rash (13%)  

Infection (81%)  

Upper respiratory infections (65%)  

Injection site reactions (43%)  

Non-upper respiratory infections (54%)  

1-10%  

Urticaria (2%)  

Hypersensitivity (1%)  

Pruritus (5%)  

Pyrexia (2%)  

Post marketing Reports  

Pancytopenia  

Leukopenia  

Neutropenia  

Thrombocytopenia  

Lymphadenopathy  

aplastic anemia  

Congestive heart failure  

Inflammatory bowel disease (IBD  

Angioedema  

Pregnancy warnings:    
Pregnancy Category: N/A  

Lactation: known 

Pregnancy Categories:       

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first trimester or the later trimester       
• Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women       
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women       
• Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits       
• Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women       
• Category N: There is no data available for the drug under this category      

Patient Information Leaflet    

Generic Name: etanercept (Rx) 

Why do we use etanercept (Rx)? 

etanercept (Rx) belongs to the class of Antirheumatics, TNF alfa inhibitors which helps to treat plaque psoriasis, Alzheimer’s disease, and joint damage in ankylosing spondylitis, rheumatoid arthritis, psoriatic arthritis.