Actions and Spectrum:
Action:
Hypoglycemic Action: acetohexamide belongs to the class of drugs known as sulfonylureas. Its primary action is to stimulate insulin release from the beta cells of the pancreas. This results in increased blood insulin levels, which helps lower elevated blood sugar levels in people with type 2 diabetes. By enabling glucose to enter cells, it plays a crucial role in improving glucose utilization and ensuring that blood glucose levels remain within a balanced and optimal range.
Spectrum:
Type 2 Diabetes: acetohexamide is specifically indicated for the treatment of type 2 diabetes, which is a condition characterized by insulin resistance and impaired insulin secretion. It is not effective in the treatment of type 1 diabetes, as it relies on the presence of functioning pancreatic beta cells to stimulate insulin release.
Mild to Moderate Diabetes: acetohexamide is typically prescribed for individuals with mild to moderate type 2 diabetes. It may not be the first choice for individuals with severe diabetes or those who are unresponsive to other treatments.