DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions:  

Frequency defined  

>10%  

Headache  

1-10%  

Eyelid ptosis  

Increased white blood cell count  

Upper respiratory tract infection   

Frequency Not Defined  

erythema  

Needle-related pain   

anxiety  

Localized pain  

Infection  

Inflammation  

Tenderness  

swelling  

  

  

Pregnancy warnings:    

• US FDA pregnancy category: Not assigned 

Breastfeeding warnings: 

• The release of the drug into the human breastmilk is unknown  
• The release of the drug into the animal milk is unknown 
• Therefore, the use of the drug is not recommended 

Pregnancy Categories:      

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first trimester or the later trimester      
• Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women      
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women      
• Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits      
• Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women      
• Category N: There is no data available for the drug under this category

Patient Information Leaflet  

Generic Name: PrabotulinumtoxinA 

Why do we use PrabotulinumtoxinA? 

PrabotulinumtoxinA belongs to the class of anticholinergic agents used temporarily to improve the appearance of moderate to severe glabellar lines.