- March 15, 2022
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Brand Name :
Magonate
Synonyms :
magnesium carbonate
Class :
Magnesium Salt Oral Electrolyte Supplement
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Brand Name :
Magonate
Synonyms :
magnesium carbonate
Class :
Magnesium Salt Oral Electrolyte Supplement
Dosage Forms & Strengths
Oral Liquid
350ml (54mg/5ml)
Oral Powder
480g (250mg/g)
Administer 5 mL orally up to 3 times a day.
Dietary recommended daily allowance (RDA) (IOM 1997) :
Adults ≥31 years:
Pregnancy: Administer 360 mg/day
Males: Administer 420 mg/day
Females: Administer 320 mg/day
Lactation: Administer 320 mg/day
19 to 30 years:
Pregnancy: Administer 350 mg/day
Males: Administer 400 mg/day
Females: Administer 310 mg/day
Lactation: Administer 310 mg/day
14 to 18 years:
Pregnancy: Administer 400 mg/day
Males: Administer 410 mg/day
Females: Administer 360 mg/day
Lactation: Administer 360 mg/day
9 to 13 years: Administer 240 mg/day
4 to 8 years: Administer 130 mg/day
1 to 3 years: Administer 80 mg/day
Dosage Forms & Strengths
Oral Liquid
350ml (54mg/5ml)
Oral Powder
480g (250mg/g)
Administer 10 to 20 mg/kg/dose four times a day; Administer 300 mg four times a day.
Note: Due to the potential of magnesium to cause diarrhea, achieving adequate magnesium levels with oral therapy may be challenging; an Intravenous supplement may be more appropriate, particularly in cases of severe shortfall.
Refer adult dosing
bismuth subcitrate, metronidazole and tetracycline
magnesium salts may decrease the absorption of tetracyclines
magnesium salts may decrease the absorption of tetracyclines
magnesium salts may decrease the absorption of tetracyclines
magnesium salts may decrease the absorption of tetracyclines
magnesium salts may decrease the absorption of tetracyclines
may have a decreased serum concentration when combined with phosphate supplements
may have a decreased serum concentration when combined with phosphate supplements
may have a decreased serum concentration when combined with phosphate supplements
tetraferric tricitrate decahydrate
may have a decreased serum concentration when combined with phosphate supplements
may have a decreased serum concentration when combined with phosphate supplements
bismuth subcitrate, metronidazole and tetracycline
may have a decreased absorption when combined with tetracyclines
may have a decreased absorption when combined with tetracyclines
may have a decreased absorption when combined with tetracyclines
may have a decreased absorption when combined with tetracyclines
may have a decreased absorption when combined with tetracyclines
l-methylfolate-pyridoxal 5′-phosphate-methylcobalamine
may reduce the levels of serum concentration of multivitamins
may reduce the level of serum concentration of quinolones
may reduce the level of serum concentration of quinolones
may diminish the serum concentration of antacids
may enhance the serum concentration of each other when combined
may diminish the absorption of magnesium salts
may diminish the serum concentration of antacids
magnesium Salts may decrease the serum concentration of Dolutegravir
magnesium Salts may decrease the serum concentration of quinolones
magnesium Salts may decrease the serum concentration of quinolones
may diminish the serum concentration of quinolones
may have an increased hypermagnesemic effect when combined with magnesium salts
may have a decreased absorption when combined with alpha-lipoic acid
may increase the serum concentration when combined with magnesium salts
may have a decreased serum concentration when combined with dolutegravir
may have a decreased serum concentration when combined with quinolones
may have a decreased serum concentration when combined with quinolones
bismuth subcitrate, metronidazole and tetracycline
may diminish the absorption when combined with tetracyclines
may diminish the absorption when combined with tetracyclines
may diminish the absorption when combined with tetracyclines
may diminish the absorption when combined with tetracyclines
may diminish the absorption when combined with tetracyclines
may diminish the serum concentration of antacids
may diminish the serum concentration of antacids
may diminish the serum concentration when combined with raltegravir
may have an increased CNS depressant effect when combined with gabapentin
may have a decreased serum concentration when combined with levothyroxine
may have a decreased serum concentration when combined with fluoride/multivitamins (with ADE)
may decrease the serum concentration of Polyvalent Cation Containing Products
may increase the antiplatelet effect of agents with antiplatelet properties
may increase the antiplatelet effect of agents with antiplatelet properties
may increase the antiplatelet effect of agents with antiplatelet properties
may increase the antiplatelet effect of agents with antiplatelet properties
may increase the antiplatelet effect of agents with antiplatelet properties
magnesium salts may increase the effect of neuromuscular-blocking agents
magnesium salts may increase the effect of neuromuscular-blocking agents
magnesium salts may increase the effect of neuromuscular-blocking agents
magnesium salts may increase the effect of neuromuscular-blocking agents
magnesium salts may increase the effect of neuromuscular-blocking agents
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased the neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may increase the effect of neuromuscular-blocking agents
may reduce the rate of absorption of tetracyclines
may reduce the rate of absorption of tetracyclines
may reduce the rate of absorption of tetracyclines
may increase the neuromuscular-blocking effect of Magnesium Salts
may increase the neuromuscular-blocking effect of Magnesium Salts
may increase the neuromuscular-blocking effect of Magnesium Salts
may increase the neuromuscular-blocking effect of Magnesium Salts
may increase the neuromuscular-blocking effect of Magnesium Salts
it may enhance the risk of side effects when combined with misoprostol
It may increase the neuromuscular-blocking effect of Neuromuscular-Blocking Agents
It may increase the neuromuscular-blocking effect of Neuromuscular-Blocking Agents
It may increase the neuromuscular-blocking effect of Neuromuscular-Blocking Agents
It may increase the neuromuscular-blocking effect of Neuromuscular-Blocking Agents
It may increase the neuromuscular-blocking effect of Neuromuscular-Blocking Agents
may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents
may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents
may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents
may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents
may enhance the neuromuscular-blocking effect of neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may have an increased neuromuscular-blocking effect when combined with neuromuscular-blocking agents
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
may decrease the levels of serum concentration
Actions and Spectrum:
Frequency defined
None
Black box warning:
None
Contraindications/caution:
Contraindications:
Caution:
Pregnancy consideration: Insufficient data available
Lactation: Excretion of the drug in human breast milk is known
Pregnancy category:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Pharmacokinetics:
Absorption
magnesium carbonate is an oral preparation of magnesium, and its absorption primarily occurs in the small intestine. Like other forms of magnesium, magnesium carbonate is absorbed through active transport and passive diffusion processes in the distal small intestine, mainly the ileum.
Distribution
Once absorbed, magnesium is distributed throughout the body via the bloodstream. Magnesium ions are essential for various physiological processes and involve numerous biochemical reactions in cells and tissues.
Metabolism
magnesium carbonate is not metabolized in the body; it remains in its chemical form until excretion.
Elimination and Excretion
magnesium carbonate is primarily eliminated from the body through the urine. The kidneys filter magnesium from the blood and excrete it into the urine. Some small amounts of magnesium may also be excreted through the feces.
Administration:
Oral administration
Take magnesium carbonate by mouth with a full glass of water. It is usually taken after meals or as needed to relieve heartburn, acid indigestion, and upset stomach.
Patient information leaflet
Generic Name: magnesium carbonate
Why do we use magnesium carbonate?
magnesium carbonate has various uses, primarily due to its antacid properties and role as a magnesium supplement. Here are some common uses of magnesium carbonate:
