Brand Name :
Tivicay, Tivicay PD
Synonyms :
dolutegravir
Class :
Antiviral agents and Anti-HIV (antiretroviral)
Dosage Forms & Strengths
Tablet, Oral:
10 mg
25 mg
50 mg
Tablet Soluble, Oral:
5 mg
Note: Dolutegravir is preferred to be given in combination with lamivudine.
Dosage Forms & Strengths
Tablet, Oral:
10 mg
25 mg
50 mg
Tablet Soluble, Oral:
5 mg
it may decrease the serum concentration of dolutegravir
magnesium Salts may decrease the serum concentration of Dolutegravir
magnesium Salts may decrease the serum concentration of Dolutegravir
magnesium Salts may decrease the serum concentration of Dolutegravir
magnesium Salts may decrease the serum concentration of Dolutegravir
magnesium Salts may decrease the serum concentration of Dolutegravir
may have a decreased serum concentration when combined with dolutegravir
may have a decreased serum concentration when combined with dolutegravir
may have a decreased serum concentration when combined with dolutegravir
may have a decreased serum concentration when combined with dolutegravir
may have a decreased serum concentration when combined with dolutegravir
may diminish the serum concentration of iron preparations
may diminish the serum concentration of polyvalent cation-containing products
rifampinin: they may diminish the serum concentration of dolutegravir
may enhance the serum concentration of metformin
may diminish the absorption of Antacids
antiviral Agents may enhance the hypoglycemic effect of anti-diabetic Agents
antiviral Agents may enhance the hypoglycemic effect of anti-diabetic Agents
antiviral Agents may enhance the hypoglycemic effect of anti-diabetic Agents
antiviral Agents may enhance the hypoglycemic effect of anti-diabetic Agents
antiviral Agents may enhance the hypoglycemic effect of anti-diabetic Agents
may diminish the anticoagulant effect of Vitamin K Antagonists
may diminish the anticoagulant effect of Vitamin K Antagonists
may diminish the anticoagulant effect of Vitamin K Antagonists
may diminish the anticoagulant effect of Vitamin K Antagonists
may diminish the anticoagulant effect of Vitamin K Antagonists
may enhance the hypoglycemic effect of antidiabetic agents
may enhance the hypoglycemic effect of antidiabetic agents
may enhance the hypoglycemic effect of antidiabetic agents
Antivirals may diminish the therapeutic effect of Talimogene Laherparepvec.
rifabutin: they may diminish the serum concentration of dolutegravir
it increases the concentration of metformin in the serum
Frequency defined:
>10%
Increased serum lipase
1% to 10%:
Pruritis
Hyperglycemia
Flatulence
Diarrhea
Upper abdominal pain
Hepatitis
Nausea
Vomiting
Depression
Headache
Suicidal ideation
Renal insufficiency
<1%:
Skin rash
Hypersensitivity reaction
Abnormal dreams
Dizziness
Frequency not defined:
Increased HDL cholesterol
Increased serum triglycerides
Increased serum creatinine
Post-marketing:
Diabetes mellitus
Acute hepatic failure
Anxiety
Arthralgia
Myalgia
Pregnancy consideration: Dolutegravir can transfer across the human placenta.
Lactation: Dolutegravir can be present in breast milk.
Pregnancy category:
Patient information leaflet
Generic Name: Dolutegravir
Pronunciation: Dolutegravir
Why do we use Dolutegravir?
It is used to treat viral infections such as HIV infection.
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