Mechanism of action
It is a fluoroquinolone antibiotic. It works by inhibiting the activity of two enzymes, DNA gyrase and topoisomerase IV, which are essential for the replication, transcription, and repair of bacterial DNA.
Spectrum
The spectrum of activity of gemifloxacin includes coverage against a range of gram-negative and gram-positive bacteria, including Haemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis, and Legionella pneumophila, among others.
It treats various bacterial infections, including respiratory tract infections, urinary tract infections, and skin and soft tissue infections. Importantly, fluoroquinolones, including gemifloxacin, have limited efficacy against anaerobic bacteria and do not cover all types of bacteria.
