- November 10, 2022
- Newsletter
- 617-430-5616
Menu
Brand Name :
Tranxene T-Tab,Tranxene SD
Synonyms :
Class :
Anti-anxiety ,Benzodiazepine
Dosage Forms & Strengths
Tablet-Schedule IV:
3.75mg,7.5mg,15mg
30
mg
Orally
once a day
Tablet
Adjust dose in the range of 15-60 mg/kg
7.5
mg
Orally
every 8 hrs
Tablet
increase by <5mg/kg
Maximum 90 mg/kg
Day 1:
30
mg
Orally
once a day
Tablet
later 30-60mg in divided doses. Do not exceed 90mg
Day 2: 45-90mg orally in divided doses
Day 3:22.5-45 mg orally in divided doses
Day 4: 15-30 mg orally in divided doses
Day 5:7.5-15 mg orally in divided doses
Tablet-Schedule IV:
3.75mg,7.5mg,15mg
< 9 years:
Not recommended
9-12 years:7.5mg orally twice a day initially; maximum dose-60mg
>12 years: Adult dosing
< 9 years:
Not recommended
9-12 years:7.5mg orally twice a day initially; maximum dose-60mg
>12 years: Adult dosing
may increase the level by affecting the hepatic enzyme CYP3A4 metabolism
may decrease the level by affecting hepatic enzyme CYP3A4 metabolism
may increase the level by affecting the hepatic enzyme CYP3A4 metabolism
may increase the level by affecting the hepatic enzyme CYP3A4 metabolism
may decrease the level by affecting hepatic enzyme CYP2C9 metabolism
it may increase the effects of each other
may increase the risk of sedation
may increase the level by affecting hepatic enzyme CYP3A4 metabolism
may increase the level by affecting hepatic enzyme CYP3A4 metabolism
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
may increase the level by affecting hepatic enzyme CYP3A4 metabolism
when combined, it may increase sedation
may decrease the level by affecting hepatic enzyme CYP3A4 metabolism
when combined, it may increase sedation
may decrease the level by affecting hepatic enzyme CYP3A4 metabolism
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
may increase the level by affecting hepatic enzyme CYP3A4 metabolism
when combined it may increase sedation
when combined it may increase sedation
when combined it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
may increase the level by affecting the hepatic enzyme CYP3A4 metabolism
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
when combined, it may increase sedation
May enhances the effects of the other by pharmacodynamic synergism
may enhance the levels of clorazepate by decreasing the metabolism
may enhance the levels of clorazepate by decreasing the metabolism
May enhances the effects of the other by pharmacodynamic synergism
Frequency defined:
Frequency Not Defined
Drowsiness
Dizziness
Nervousness
Headache
Confusion
GI complaints
Dry mouth
Blurred vision
Narrow-angle glaucoma
Documented hypersensitivity
Pregnancy consideration: Not available
Pregnancy category: D
Lactation: The drug is excreted into the breast milk; nursing is not recommended
Pregnancy category:
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.
Category B: There is no evidence of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women.
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh risks over benefits. These category drugs should be prohibited for pregnant women.
Category N: There is no data available for the drug under this category.
Patient information leaflet
Generic Name:Clorazepate
Pronounced: [ klor-AZ-e-pate]
Why do we use clorazepate?
Clorazepate treats anxiety disorders, alcohol withdrawal symptoms, and partial seizures.