DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions:

Frequency Defined

1-10% 

Depression 

Diarrhea 

Pruritus  

Bradycardia 

Dizziness  

Headache  

Tiredness 

Rash 

Heart failure 

Hypotension 

Dyspnea  

Cold extremities 

Heartburn  

Xerostomia  

Wheezing  

Bronchospasm 

Constipation  

Nausea 

Flatulence  

Frequency not defined 

Raynaud phenomenon 

Decreased exercise tolerance 

Pregnancy warnings:  

AU TGA pregnancy category: C

US FDA pregnancy category: C

Breastfeeding warnings:

The release of the drug into the human breastmilk is known

Pregnancy Categories:    

Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.

Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women

Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women

Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits

Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.

Category N: There is no data available for the drug under this category

 

Patient Information Leaflet

Generic Name: metoprolol

Pronounced: MET-oh-PROE-lol

Why do we use metoprolol?

Metoprolol is an anti-hypertensive drug belonging to the subclass beta-blocker used to treat hypertension, angina, and heart failure. It mainly helps decrease high blood pressure and helps from the risk of heart attacks, strokes, and kidney diseases.