donepezil transdermal

DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions:   

Frequency Defined  

>10%  

Erythema   

Papules   

Headache   

1-10%  

Muscle spasms   

Insomnia  

Abdominal pain   

Application site dermatitis   

Constipation   

Diarrhea   

Application site pain  

Dizziness   

Abnormal dreams  

Skin laceration   

<1%  

Edema   

Post marketing Reports:  

Hemolytic anemia  

Heart block   

QTc prolongation  

Abdominal pain  

Cholecystitis  

Hepatitis  

pancreatitis  

Hyponatremia  

Pregnancy warnings:    
US FDA Pregnancy Category: N/A 

Breastfeeding warnings:  

crosses into breast milk- Unknown 

Pregnancy Categories:       

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first trimester or the later trimester       
• Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women       
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women       
• Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits       
• Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women       
• Category N: There is no data available for the drug under this category      

Patient Information Leaflet    

Generic Name: donepezil transdermal 

Why do we use donepezil transdermal? 

donepezil transdermal belongs to the class of Acetylcholinesterase Inhibitors, which helps to treat Alzheimer’s disease and Dementia