Brand Name :
Gonitro, nitromist, nitrostat, nitrolingual, nitro-time
Synonyms :
Glyceryl trinitrate
Class :
Antianginal agents, vasodilators
Dosage Forms & Strengths
Capsule-extended release:
2.5,6.5,9 mg
Sub-lingual powder:
400mcg
Sublingual tablet:
0.3mg,0.4mg,0.6mg.
2.5 - 6.5
mg
Oral
every 8 hrs
Capsules
Dose Adjustments
Creatinine clearance:
10-50mg/min-administer every 24-72 hour
<10ml/min-administer every 72-96 hour
FDA not approved
may have an increased hypotensive effect when combined with apomorphine
may decrease the vasodilatory effect when combined with nitroglycerin
may decrease the vasodilatory effect when combined with nitroglycerin
may decrease the vasodilatory effect when combined with nitroglycerin
may decrease the vasodilatory effect when combined with nitroglycerin
may decrease the vasodilatory effect when combined with nitroglycerin
may diminish the vasodilatory effect when combined with nitroglycerin
may decrease the anticoagulant effect when combined with heparin
may diminish the serum concentration when combined with alteplase
may diminish the absorption when combined with nitroglycerin
may diminish the absorption when combined with nitroglycerin
may diminish the absorption when combined with nitroglycerin
may diminish the absorption when combined with nitroglycerin
may diminish the absorption when combined with nitroglycerin
anticholinergic agents diminish the absorption of nitroglycerin
anticholinergic agents diminish the absorption of nitroglycerin
anticholinergic agents diminish the absorption of nitroglycerin
anticholinergic agents diminish the absorption of nitroglycerin
anticholinergic agents diminish the absorption of nitroglycerin
when both drugs are combined, there may be a decrease in the serum concentration
Frequency defined:
>10%
Headache
Nervous disorders
1-10%
Peripheral edema
Abdominal pain
Asthenia
Dyspnea
Pharyngitis
Rhinitis
Dizziness
<1% post-marketing complications
Contact dermatitis
Hypoxemia
Nausea
Pallor
Palpitations
Vertigo
Vomiting
Contraindicated in hypersensitivity,acute myocardial infarction,anemia.
Pregnancy consideration: The drug crosses the placenta
Pregnancy category: C
Lactation: The drug is not secreted in the human breast milk
Pregnancy category:
Patient information leaflet
Generic Name: Nitroglycerin
Pronounced: [ NYE-troe-GLI-ser-in]
Why do we use nitroglycerin?
Nitroglycerin prevents chest pain(angina) in people with coronary artery disease.
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