Brand Name :
Activase
(United States) [Available] ,Cathflo Activase
(United States) [Available]Synonyms :
Activase
Class :
Thrombolytics
Dosage Forms & Strengths
Powder for injection:
2mg (Cathflo activase),
50mg,100mg (Activase)
Powder for injection:
2mg (Cathflo activase)
Refer adult dosing
may enhance the risk of angioedema when combined with Alteplase
when both drugs are combined, there may be an increase in the anticoagulant effect
when both drugs are combined, there may be a decrease in the therapeutic effect
when both drugs are combined, there may be a decrease in the therapeutic effect
agents with Antiplatelet Properties
when both the drugs are combined, there might be an increase in the anticoagulant effect
Converting Enzyme Inhibitors- when both drugs are combined, there might be an increase in the anticoagulant effect
when both drugs are combined, there may be an increase in the anticoagulant effect
when both drugs are combined, there may be an increase in the anticoagulant effect
when both drugs are combined, there may be an increase in adverse effects
when both drugs are combined, there may be a decrease in the serum concentration
when both drugs are combined, there may be an increase in adverse effects
when both drugs are combined, there may be a decrease in the therapeutic effect
angiotensin-converting Enzyme (ACE) inhibitors may increase the risk of adverse effects of alteplase
angiotensin-converting Enzyme (ACE) inhibitors may increase the risk of adverse effects of alteplase
angiotensin-converting Enzyme (ACE) inhibitors may increase the risk of adverse effects of alteplase
angiotensin-converting Enzyme (ACE) inhibitors may increase the risk of adverse effects of alteplase
angiotensin-converting Enzyme (ACE) inhibitors may increase the risk of adverse effects of alteplase
may have an increasingly adverse effect when combined with alteplase
may have an increasingly adverse effect when combined with alteplase
may have an increasingly adverse effect when combined with alteplase
may have an increasingly adverse effect when combined with alteplase
may have an increasingly adverse effect when combined with alteplase
It may enhance the risk of bleeding by affecting coagulation when combined with omega-3 carboxylic acids
may increase the anticoagulation when combined with ginkgo biloba
may decrease the effect of each other through pharmacodynamic antagonism
lisinopril/hydrochlorothiazide
may increase the toxic effect of Angiotensin-converting enzyme inhibitors
may diminish the serum concentration when combined with alteplase
Adverse effects
Frequency defined:
>10%
Cardiac arrest
1-10%
Intracranial hemorrhage
Cerebrovascular accidents
Frequently not defined
Sepsis
Hypotension
Bleeding
Arterial embolism
Nausea/Vomiting
Cerebral edema
Thromboembolism
Do not administer to patients with acute ischemic stroke, pulmonary embolism, concurrent drug therapy issues, or risk of internal bleeding occurs.
Pregnancy consideration:
Lactation: The release of the drug in human breast milk is unknown.
Pregnancy category:
Patient information leaflet
Generic Name: alteplase (Rx)
Pronounced: [ AL-te-plase ]
Why do we use alteplase?
Alteplase is a thrombolytic drug also known as a clot-busting drug. It is used to treat blood clots in the heart and lungs.
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Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
MASSACHUSETTS – USA
60 Roberts Drive, Suite 313,
North Adams, MA 01247
MAHARASHTRA – INDIA
7, Shree Krishna, 2nd Floor,
Opp Kiosk Koffee,
Shirole Lane, Off FC Road,
Pune 411004, Maharashtra
