Actions and spectrum:
- Inhibition of ACE: enalaprilat blocks the conversion of angiotensin I to angiotensin II. By inhibiting ACE, it helps dilate blood vessels and reduce blood pressure.
- Reduction of aldosterone secretion: enalaprilat decreases the secretion of aldosterone, a hormone that promotes sodium and water retention. This leads to diuresis (increased urine production) and helps in the management of fluid overload.
- Antihypertensive effect: enalaprilat lowers blood pressure by reducing systemic vascular resistance and increasing cardiac output.
The spectrum of enalaprilat’s actions primarily targets the cardiovascular system. It is commonly used to manage hypertension, heart failure, and certain kidney conditions.
