DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Frequency defined:  

>10% 

Dyspepsia  

Increased liver function test 

1-10% 

Dizziness  

Headache  

Nausea  

Diarrhea  

Abdominal pain  

Constipation  

Flatulence  

Peripheral edema  

Bronchospasm  

Myocardial infarction  

Stomatitis  

Insomnia  

<1% 

Congestive heart failure 

Hypertension  

Stevens-Johnson syndrome 

Gastrointestinal bleeding 

Gastrointestinal perforation 

Agranulocytosis  

Pregnancy consideration: N/A 

Pregnancy category: C  

Lactation: The excretion of the drug in human breast milk is unknown  

Pregnancy category: 

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester. 
• Category B: There is no evidence of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women. 
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women 
• Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits. 
• Category X: Drugs listed in this category outweigh risks over benefits These category drugs should be prohibited for pregnant women. 
• Category N: There is no data available for the drug under this category. 

Patient information leaflet 

Generic Name: ketoprofen 

Pronounced: [ kee-toe-PROE-fen] 

Why do we use ketoprofen? 

Ketoprofen is used to treat inflammation or pain caused by arthritis.