- March 15, 2022
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Brand Name :
Relafen
Synonyms :
Class :
NSAIDs
Dosage forms & Strengths:
Adult:
Tablet:
500 mg
750 mg
1000
mg
Orally
once a day
Tablet
In case of renal impairment, 500 mg orally once daily:
1000
mg
Orally
once a day
Tablet
Safety and efficacy are not seen in pediatrics
NSAIDs may enhance the anticoagulant effect of Heparin
NSAIDs may enhance the anticoagulant effect of Heparin
interaction with NSAIDs may lead to increased toxicity such as myelosuppression, renal toxicity, and GI toxicity
interaction with NSAIDs may lead to increased toxicity such as myelosuppression, renal toxicity, and GI toxicity
ACE Inhibitors may enhance the adverse/toxic effect of NSAIDs
ACE Inhibitors may enhance the adverse/toxic effect of NSAIDs
ACE Inhibitors may enhance the adverse/toxic effect of NSAIDs
ACE Inhibitors may enhance the adverse/toxic effect of NSAIDs
ACE Inhibitors may enhance the adverse/toxic effect of NSAIDs
it may diminish the excretion rate when combined with gadofosveset, resulting in an enhanced serum level
angiotensin II Receptor Blockers may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
angiotensin II Receptor Blockers may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
angiotensin II Receptor Blockers may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
angiotensin II Receptor Blockers may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
angiotensin II Receptor Blockers may enhance the adverse/toxic effect of Nonsteroidal Anti-Inflammatory Agents
when combined may increase anticoagulation
when combined may increase anticoagulation
when both drugs are combined, there may be an increased effect of nabumetone by acidic drug competition for renal tubular clearance
>10%:
Diarrhea
Dyspepsia
Abdominal pain
1-10%:
Constipation
Dizziness
Edema
Flatulence
Headache
Nausea
Positive stool guaiac
Pruritus
Rash
Tinnitus
Dry mouth
Fatigue
Gastritis
Increased sweating
Insomnia
Nervousness
Somnolence
Stomatitis
Vomiting
Nabumetone is contraindicated in patients hypersensitive to the formulation’s active ingredient and other excipients.
Pregnancy consideration:
Category C
Breastfeeding warnings:
Not indicated for lactating women.
Pregnancy category:
Patient information leaflet
Generic Name: nabumetone
Pronounced: na-byoo-me-tone
Why do we use nabumetone?
Nabumetone belongs to the category of NSAIDs. It treats osteoarthritis and rheumatoid arthritis.
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