- March 15, 2022
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Brand Name :
Indocin, Indocin SR, tivorbex
Synonyms :
Class :
Non-steroidal anti-inflammatory drugs
Dosage Forms & Strengths
Capsule-20mg,25mg,40mg,50mg
Capsule extended release-75mg
Powder for injection-1mg
Oral suspension-25mg/5ml
Suppository-50mg
Immediate release:
25 - 50
mg
Orally
every 12 hrs
Tablet
Do not exceed 200mg/day
Extended release-75-150mg/day orally in single dose or divided every 12 hours
Immediate release:
25 - 50
mg
Orally
every 8 hrs
Tablet
Extended release-75-150mg/day orally in single dose or divided every 12 hours
20
mg
orally
3 times a day
Tablet
40 mg orally twice a day
50
mg
Orally
every 8 hrs
3 - 5
days
Tablet
nephrogenic diabetes insipidus
2
mg/kg
Orally
every 8 hrs
Tablet
Dosage Forms & Strengths
Capsule-25mg,50mg
Capsule extended release-75mg
Powder for injection-1mg
Oral suspension-25mg/5ml
Suppository-50mg
<2 years: safety and efficacy not established
2-14 years:1-2mg/kg/day orally every 6-12hours.Do not exceed 4mg/kg/day
>14 years:25-50 mg orally/per rectum every 8-12 hours
may increase the risk or severity of hypertension when combined
when combined may increase anticoagulation
may diminish the effects of indomethacin by pharmacodynamic antagonism
may diminish the effects of indomethacin by pharmacodynamic antagonism
may diminish the effects of indomethacin by pharmacodynamic antagonism
may diminish the effects of indomethacin by pharmacodynamic antagonism
may diminish the effects of indomethacin by pharmacodynamic antagonism
may diminish the effects of indomethacin by pharmacodynamic antagonism
may diminish the effects of indomethacin by pharmacodynamic antagonism
may diminish the effects of indomethacin by pharmacodynamic antagonism
increases the serum level of pemetrexed
increases the serum level of pralatrexate
it enhances the serum potassium levels
may diminish the effects of indomethacin by pharmacodynamic antagonism
may diminish the effects of indomethacin by pharmacodynamic antagonism
it enhances the serum potassium levels
when combined may increase anticoagulation
may diminish the effects of indomethacin by pharmacodynamic antagonism
it enhances the serum potassium levels
may increase the level of each other by an unknown mechanism
when combined may increase anticoagulation
when combined may increase anticoagulation
it enhances the serum potassium levels
may increase the level of each other by an unknown mechanism
may decrease the therapeutic effect when combined with glucagon and its analogs
may decrease the therapeutic effect when combined with glucagon and its analogs
may decrease the therapeutic effect when combined with glucagon and its analogs
may decrease the therapeutic effect when combined with glucagon and its analogs
Combining Indomethacin with pranlukast may cause a reduction in the Indomethacin’s metabolism
May enhances the effects of the other by pharmacodynamic synergism
may enhance the renal tubular clearance for anionic drug competition
may enhance the renal tubular clearance for anionic drug competition
may diminish the effects of indomethacin by pharmacodynamic antagonism
may enhance the renal tubular clearance for anionic drug competition
Frequency defined:
>10%
Renal insufficiency
Jaundice
Elevated liver function test values
1-10%
Dizziness
Dyspepsia
Epigastric pain
Indigestion
Nausea
Constipation
Depression
Diarrhea
Fatigue
<1%
Angioedema
Aplastic anemia
Asthma
Bone marrow depression
Congestive heart failure
Pulmonary edema
Thrombocytopenic purpura
Ulcerative stomatitis
Leukopenia
Macular and morbilliform eruptions
Post-marketing Reports
Pancreatitis
Pregnancy consideration: C
Lactation: The drug is excreted in the human breast milk
Pregnancy category:
Patient information leaflet
Generic Name: indomethacin
Pronounced: (in doe meth’ a sin)
Why do we use indomethacin?
Indomethacin is used to treat mild to moderate acute pain and relieves symptoms of gout and arthritis.
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USA – BOSTON
60 Roberts Drive, Suite 313
North Adams, MA 01247
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7, Shree Krishna, 2nd Floor, Opp Kiosk Koffee, Shirole Lane, Off FC Road, Pune 411004, Maharashtra
Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
MASSACHUSETTS – USA
60 Roberts Drive, Suite 313,
North Adams, MA 01247
MAHARASHTRA – INDIA
7, Shree Krishna, 2nd Floor,
Opp Kiosk Koffee,
Shirole Lane, Off FC Road,
Pune 411004, Maharashtra
