DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions:   

Frequency Defined  

>10%  

Hypertension, adult  

Dry cough  

Arthralgia (3%)  

Fatigue (3%)  

Hyperkalemia (2%)  

Hypotension, postural (2%)  

Dizziness (17%)  

Hypotension (7%)  

Dizziness, postural (2%)  

1-10%  

Increased serum creatinine ≥50% (3.9%)  

Heart failure  

>1%  

Nausea  

Headache  

Renal impairment  

Syncope  

Upper abdominal pain  

Vertigo  

Blurred vision  

Post MI H4  

Neutropenia (1.9%)  

Increased serum creatinine ≥50% (4.2%)  

Hypotension NOS (1.4%)  

<1%  

Old MI  

Increased blood creatinine (0.6%)  

Cough (0.6%)  

Rash NOS (0.2%  

Pregnancy warnings:     

AU TGA pregnancy category: D 

US FDA pregnancy category: Not assigned. Lactation: 

Excreted into human milk is Unknown 

Pregnancy Categories:       

Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.       

Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women       

Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women       

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.       

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.       

Category N: There is no data available for the drug under this category 

Patient Information Leaflet    

Generic Name: valsartan 

Why do we use valsartan? 

valsartan is an Angiotensin receptor blocker which is used to treat hypertension, heart attack, and myocardial infarction.