DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions:   

Frequency Defined  

>10%  

Hyperkalemia (19%)  

1-10%  

Dizziness (10%)  

Fatigue (4%)  

Diarrhea (3%)  

Orthostatic hypotension (5%)  

Dyspepsia (2%)  

Upper respiratory tract infection (9%)  

Post marketing Reports  

Urticaria  

angioedema   

elevated liver function test results  

Jaundice  

Hepatitis   

Hyperkalemia  

Thrombocytopenia   

 

Pregnancy warnings:     

AU TGA pregnancy category: D 

US FDA pregnancy category: Not assigned. Lactation: 

Excreted into human milk is Unknown 

Pregnancy Categories:       

Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.       

Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women       

Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women       

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.       

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.       

Category N: There is no data available for the drug under this category 

Patient Information Leaflet    

Generic Name: irbesartan 

Why do we use irbesartan? 

irbesartan is an Angiotensin receptor blocker which is used to treat hypertension and diabetic nephropathy.