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amlodipine/telmisartan

Brand Name :

Twynsta

Synonyms :

amlodipine/telmisartan

Class :

Angiotensin receptor II inhibitors, Calcium channel blockers





No data available for drug.

Mechanism of action

amlodipine is a calcium channel blocker that works by blocking the entry of calcium into the cells of the blood vessels, thereby relaxing the blood vessels and allowing for better blood flow. This results in a decrease in blood pressure. amlodipine has a broad spectrum of activity and can effectively lower blood pressure in patients with mild to moderate hypertension
telmisartan, on the other hand, is an angiotensin receptor blocker (ARB) that works by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow.

By blocking the action of angiotensin II, telmisartan helps to dilate blood vessels and lower blood pressure. It also effectively reduces the risk of cardiovascular events such as heart attack and stroke. When used together, amlodipine and telmisartan provide additive blood pressure-lowering effects, making them an effective combination therapy for the treatment of hypertension. The combination of these two medications has been shown to effectively lower blood pressure in many patients, including those with severe hypertension and those who have not achieved adequate blood pressure control with monotherapy

Spectrum

The combination of amlodipine and telmisartan has a broad spectrum of activity and is used to treat hypertension (high blood pressure) in many patients. The combination therapy is particularly effective in patients who have not achieved adequate blood pressure control with monotherapy or who have severe hypertension

DRUG INTERACTION

amlodipine/telmisartan

&

  • patisiran
  • imetelstat
  • phenylephrine ophthalmic
  • myoinositol
  • vasicinone
  • soda lime
  • fisetin
  • Reynoutria Japonica
  • Coco Monoethanolamide
  • Betadex
  • lithopone
  • cyperus rotundus
  • papaya juice
  • 1-naphthaleneacetic acid
  • Nordazepam
  • Glechoma hederacea
  • Alternanthera sessilis
  • nicofetamide
  • napthol asol
  • cocamidopropyl betaine
  • musa x paradisiaca
  • dicyclomine/mefenamic acid
  • Sorghum
  • Manganese citrate
  • tovorafenib
  • mefenamic acid/paracetamol
  • eschscholzia californica
  • canna indica root
  • tranexamic acid/mefenamic acid
  • dexverapamil
  • sitogluside
  • secalciferol
  • cefatrizine
  • Sedum Acre
  • Flurogestone
  • Fluocortin
  • Bifendate
  • piprozolin
  • aminacrine undecylate
  • ethylenediamine mandelate
  • pelubiprofen
  • hesperetin
  • butethamine
  • epitiostanol
  • androstenediol
  • Nitroxoline
  • Iocarmic acid
  • Capobenic acid
  • dordaviprone (investigational drug)
  • Vitexin
  • Friluglanstat (investigational drug)
  • scorias spongiosa
  • Luseogliflozin
  • indoxacarb
  • prademagene zamikeracel
  • fidanacogene elaparvovec-dzkt
  • albifylline
  • idanpramine
  • araneus diadematus
  • Sulfamazone
  • Lycosa tarantula
  • malotilate
  • Ethacizine
  • Namilumab
  • Latrunculin B
  • stachyose
  • platinic oxide
  • iopronic acid
  • calcium chloride / potassium chloride/lactic acid/ sodium chloride/sodium hydroxide/sodium lactate solution
  • citric acid/ sodium bicarbonate/ sodium carbonate anhydrous
  • vadadustat
  • permethrin medical grade cis/trans isomers 25/75
  • lutetium, isotope of mass 177
  • human normal immunoglobulin
  • sacrosidase
  • apadamtase alfa, recombinant
  • acetyl hexapeptide-8 amide
  • pemivibart (Investigational)
  • govorestat
  • Zanidatamab
  • sotatеrcеpt
  • MV 140 vaccine
  • leuprorelin implant
  • cinchocaine hydrochloride/fluocortolone hexanoate/fluocortolone pivalate
  • Beautyberry
  • risedronate/calcium/vitamin D3
  • rhubarb extract/senna leaf/sulphur purified/wood charcoal
  • boric acid/kaolin/methyl salicylate/peppermint oil/thymol
  • docosahexaenoic acid/eicospentaenoic acid
  • aluminium hydroxide/magnesium hydroxide/simethicone
  • gentamicin/hydrocortisone
  • succinylcholine
  • sinefungin
  • letibotulinumtoxinA
  • coal tar/coconut oil/salicylic acid
  • camphor/camphor oil white/capsicum oleoresin /menthol/methyl salicylate
  • thioglycolic acid
  • acetic acid auricular
  • roluperidone
  • hydrocortisone/crotamiton topical
  • nystatin/chlorhexidine
  • aluminium chloride hexahydrate
  • ketoprofen topical
  • Chlormethine
  • podophyllotoxin
  • urea/lactic acid
  • autologous chondrocytes implant
  • afelimomab
  • gepotidacin
  • fludroxycortide
  • fentanyl transdermal
  • erythromycin/zinc acetate
  • dibotermin alfa powder
  • desferrioxamine mesilate
  • choline salicylate/magnesium salicylate
  • castor oil/peru balsam/trypsin
  • betamethasone/dexchlorpheniramine maleate
  • benzalkonium chloride solution/cetrimide
  • barzolvolimab
  • ascorbic acid / calcium laevulinate / nicotinamide / calcium pantothenate / calcium chloride / riboflavine / pyridoxine hydrochloride / thiamine hydrochloride
  • argipressin
  • arachis oil refined/chlorobutanol hemihydrate
  • arachis oil/eucalyptol/nutmeg oil/terpineol
  • ammonium chloride/diphenhydramine hydrochloride/levomenthol
  • amino acid mixture d / calcium chloride dihydrate / glucose monohydrate / glycine / magnesium chloride hexahydrate / olive oil / potassium chloride / sodium acetate trihydrate / sodium glycerophosphate pentahydrate / soya-bean oil
  • biotin/colecalciferol/copper (ii)sulfate dried/ cyanocobalamine/ dl-alpha tocopherol acetate/dibasic calcium phosphate anhydrous/folic acid/iron (ii)sulfate dried/ lecithin/ magnesium sulfate dried/ nicotinamide/ pyridoxine hydrochloride/ riboflavin
  • ampicillin sodium / cloxacillin sodium
  • undecylenic acid, undecylenate salts, zincundecate
  • omeprazole/sodium bicarbonate
  • efgartigimod alfa/hyaluronidase
  • xylometazoline/ipratropium
  • cefepime and enmetazobactam
  • isotonic sodium chloride
  • bee venom allergen injection
  • fentanyl intranasal
  • alglucosidase alfa
  • triprolidine/pseudoephedrine
  • pegademase bovine
  • castor oil and peru balsam
  • camphor/eucalyptus oil/menthol
  • oxyquinoline/sodium lauryl sulfate
  • somatorelin
  • menotrophin injection
  • menadiol
  • hylan g-f 20
  • cefepime and taniborbactum
  • water avens
  • camphor/menthol
  • acoramidis
  • elafibranor
  • arrowroot
  • miconazole nitrate/hydrocortisone
  • vildagliptin/metformin
  • dobesilic acid
  • aroxybutynin and atomoxetine
  • hygromycin
  • linvoseltamab
  • nemolizumab
  • aceprometazine
  • limaprost
  • oxazolam
  • trimegestone
  • teceleukin
  • beauty berry
  • dinotefuran
  • imiprothrin
  • transfluthrin
  • thymalfasin
  • technetium Tc 99m tilmanocept
  • glepaglutide
  • marstacimab
  • pixantrone
  • Andiroba
  • arabinoxylan
  • arenaria rubra
  • etripamil
  • jequirity
  • jiaogulan
  • dusquetide
  • rolipram
  • tradipitant
  • sinfungin
  • diclofenac/omeprazole
  • brinzolamide and timolol maleate
  • wormseed
  • wormwood
  • wood sorrel
  • carmellose sodium
  • ibandronic acid
  • cinnarizine and dimenhydrinate
  • ursodeoxycholic acid
  • rhubarb extract/salicylic acid
  • butamirate citrate
  • fumitory
  • taheebo
  • uva ursi
  • vervain
  • coleus
  • coltsfoot
  • crampbark
  • plantain
  • potassium nitrate and silver nitrate
  • gelsemium
  • gentian
  • glucomannan
  • walnut
  • meadowsweet
  • midomafetamine
  • pennyroyal
  • periwinkle
  • betony
  • bitter orange
  • bladderwrack
  • bloodroot
  • emu oil
  • garcinia
  • yellow dock
  • burdock
  • dehydroepiandrosterone
  • aucubin
  • jasmone
  • resacetophenone
  • ecamsule ditriethanolamine
  • feclobuzone
  • fenoprop triethanolamine
  • verdyl acetate
  • caffeic acid
  • cyclamen aldehyde
  • dicetyldimonium chloride
  • wogonin
  • impacarzine
  • laurylpyridinium chloride
  • stepronin
  • matrine
  • sakuranin
  • cannabichromene
  • sandalore
  • sabinene
  • oxypaeoniflora
  • ethylhexyl pelargonate
  • acrylonitrile
  • allyl alcohol
  • dipalmitoylethyl hydroxyethylmonium methosulfate
  • butidrine
  • clothiapine
  • propanediol dicaprylate
  • buchu
  • undecanol
  • enilconazole
  • xymenynic acid
  • angelica
  • nizubaglustat
  • resomelagon
  • ulecaciclib
  • apple cider vinegar
  • bacopa
  • barley grass
  • dandelion
  • deer velvet
  • dolomite
  • bugleweed
  • bupleurum
  • glyceryltrinitrate
  • pociredir
  • asnuciclib
  • actalycabtagene autoleucel
  • butantan–dengue vaccine
  • travoprost/timolol
  • furosemide/potassium chloride
  • amylamine
  • jaborandi
  • patritumab deruxtecan
  • jackfruit
  • sterculia
  • ascorbigen
  • ashitaba
  • androstenetrione
  • andrachne
  • cosibelimab
  • racecadotril
  • neomycin/chlorhexidine
  • octocog alfa
  • cetrimide
  • ispaghula husk
  • polyhexanide
  • octenidine
  • polygeline
  • heparinoid
  • jewelweed
  • boldo
  • anizatrectinib
  • alpinia
  • henbane
  • cynanchum vincetoxicum root and sulfur
  • boditrectinib
  • izumerogant
  • zavondemstat
  • abuta
  • fadogia agrestis
  • fly agaric mushroom
  • meptazinol
  • methoxyflurane
  • tramadol/dexketoprofen
  • betaine/polyhexanide
  • filgotinib
  • inosine acedoben dimepranol
  • alverine citrate
  • hyoscine butylbromide
  • senna+ ispaghula
  • cabbage palm
  • cajeput oil
  • calanus oil
  • calamint
  • canada balsam
  • carnosine
  • alverine citrate/simeticone
  • dihydroartemisinin/piperaquine
  • mebeverine/ispaghula
  • calcipotriol
  • tacalcitol
  • triethyl citrate/ethyl linoleate
  • sodium dilauramidoglutamide lysine
  • fazamorexant
  • avibactam tomilopil and ceftibuten
  • drostanolone
  • tigilanol tiglate
  • isorhynchophylline
  • rhynchophylline
  • crisugabalin
  • epigallocatechin gallate
  • clomocycline
  • corynoxeine
  • isocorynoxeine
  • Culmerciclib
  • Neladenoson
  • ambrein
  • hexylcaine
  • phensuximide
  • resencatinib (investigational)
  • rolusafine
  • pumecitinib
  • arhalofenic acid
  • berdazimer sodium
  • benzquinamide
  • clidinium
  • sulfametopyrazine
  • fulzerasib (Investigational Drug)
  • rovadicitinib (Investigational Drug)
  • Upleganan (Investigational Drug)
  • menthyl ethylamido oxalate
  • quaternium-90 montmorillonite
  • unecritinib (investigational drug)
  • etohexadiol
  • guaiol
  • proximadiol
  • verdinexor
  • sofnobrutinib
  • talbutal
  • ethoxzolamide
  • propiomazine
  • enprofylline
  • phenmetrazine
  • merigolix
  • pralurbactam
  • neracorvir
  • vonifimod
  • apaziquone hydroquinone
  • darizmetinib
  • zandelisib
  • xininurad
  • ritivixibat
  • amiselimod phosphate (investigational drug)
  • emzeltrectinib (investigational drug)
  • ficonalkib
  • cinalukast
  • ulobetasol
  • candoxatril
  • nitrofural
  • acetyldigitoxin
  • bentiromide
  • dextrothyroxine
  • chlorotrianisene
  • remikiren
  • pipobroman
  • vidarabine
  • immune globulin intravenous, human-stwk
  • spermine
  • serine
  • N-acetyl glucosamine
  • valine
  • adenine
  • asparagine
  • citrulline
  • adinazolam
  • interferon alfacon-1
  • interferon alfa-n1
  • felypressin
  • birch triterpenes
  • pyridoxal phosphate
  • technetium Tc-99m arcitumomab
  • beta-alanine
  • dihomo-gamma-linolenic acid
  • urea/hydrocortisone
  • R21/Matrix-M vaccine
  • povidone-iodine (ophthalmic)
  • pheniramine
  • hydrocortisone rectal
  • chloroxylenol/pramoxine/zinc acetate
  • chloroxylenol/pramoxine
  • dextrose/sucrose/vitamin C/zinc sulphate
  • furazolidone/metronidazole/dicyclomine
  • ergocalciferol (vitamin D2)
  • benoxaprofen (discontinued)
  • teicoplanin
  • carbomer
  • chromic chloride / iron (ii) chloride tetrahydrate / potassium iodide / manganese chloride / sodium fluoride / sodium selenite pentahydrate / sodium molybdate dihydrate / zinc chloride/ cupric chloride
  • bufylline
  • lidocaine/prilocaine
  • opium tincture, squill oxymel
  • dibrompropamidine
  • metronidazole/tetracycline/bismuth subsalicylate
  • agnus- castus
  • velaglucerase alfa
  • alendronic acid / colecalciferol
  • bimatoprost / timolol
  • efbemalenograstim alfa
  • dried ferrous sulfate/folic acid
  • dried ferrous sulfate / sodium ascorbate
  • nirogacestat
  • soya-bean oil, medium-chain triglycerides
  • demeclocycline hydrochloride and triamcinolone acetonide
  • fusidic acid / hydrocortisone acetate
  • macrogol
  • storax, benzoin
  • nomegestrol acetate/estradiol
  • flumetasone pivalate/ clioquinol
  • berdazimer topical (Pending FDA Approval)
  • buflomedil
  • butobarbital
  • andexanet alfa
  • methoxypolyethylene glycol-epoetin beta
  • viscum abietis
  • pramoxine vaginal
  • bupivacaine implant
  • cromolyn sodium, inhaled
  • pneumococcal vaccine 20-valent
  • bimatoprost ophthalmic implant
  • tick-borne encephalitis vaccine
  • chloroprocaine ophthalmic
  • travoprost intraocular implant (Pending FDA approval)
  • typhoid polysaccharide vaccine
  • sodium phosphate rectal
  • human papillomavirus vaccine, nonavalent
  • peanut immunotherapy epicutaneous (FDA approval pending)
  • cromolyn sodium, intranasal
  • red blood cells(Blood component)
  • oral mucoadhesive
  • clindamycin vaginal
  • whole blood (Blood Component)
  • fibrinogen/thrombin
  • levothyroxine/liothyronine
  • ipratropium intranasal
  • metronidazole vaginal
  • cyamemazine
  • brinase
  • reviparin
  • ulinastatin
  • saruplase
  • acepromazine
  • emylcamate
  • methionine
  • amino acids and electrolytes in dextrose with calcium
  • slippery elm
  • camostat
  • hemoglobin crosfumaril
  • moperone
  • chlormidazole
  • brilaroxazine
  • palopegteriparatide
  • diazepam buccal
  • benegrastim (pending for FDA approval)
  • COVID-19 vaccine, adjuvanted-Novavax
  • vestronidase alfa-vjbk
  • tebipenem (Pending FDA Approval)
  • tislelizumab (Pending FDA Approval)
  • zolbetuximab (Pending FDA Approval)
  • zoliflodacin (pending FDA approval)
  • zibotentan and dapagliflozin
  • fluorine F18 DCFPyL
  • debamestrocel
  • givinostat
  • amubarvimab and romlusevimab(Pending FDA Approval)
  • sabizabulin(Pending FDA approval)
  • fexapotide(Phase 3 Clinical trial)
  • diatrizoic acid
  • drotaverine
  • diethyl phthalate
  • enclomiphene
  • epalrestat
  • ethamsylate
  • flupirtine
  • imidurea
  • sodium glycolate
  • feracrylum
  • ethacridine
  • furazolidone/metronidazole
  • ozagrel hydrochloride
  • leptazol
  • l-glutamic acid /vitamin B complex
  • etizolam
  • etizolam/propranolol
  • ethoheptazine citrate
  • etophylline and theophylline
  • etophylline
  • finger millet
  • drotaverine/mefenamic acid
  • dichloroxylenol
  • pneumococcal 7-valent vaccine
  • diclofenac and metaxalone
  • dipivefrin ophthalmic
  • enbucrilate
  • potassium citrate and citric acid
  • potassium gluconate
  • aclarubicin
  • alfuzosin/dutasteride
  • adrenochrome monosemicarbazone
  • selenium sulfide topical
  • sertaconazole
  • amorolfine cream
  • amsacrine
  • amylmetacresol
  • sulfonated phenolics in aqueous solution
  • technetium Tc-99m sulfur colloid
  • raltitrexed
  • romiplostim
  • acediasulfone
  • azulene
  • acebrophylline
  • clonazepam/escitalopram oxalate
  • allylestrenol
  • andrographolide
  • artemotil
  • technetium Tc-99m sestamibi
  • rubidium Rb-82
  • somapacitan
  • sodium sulfate, magnesium sulfate and potassium sulfate
  • almitrine
  • gramicidin
  • nikethamide
  • technetium Tc-99m sodium pertechnetate
  • betiatide
  • prilocaine/epinephrine
  • amlexanox
  • acetaminophen/salicylamide/phenyltoloxamine
  • neomycin topical
  • zilucoplan
  • antazoline and xylometazoline
  • toripalimab
  • iron isomaltoside
  • meningococcal A C Y and W polysaccharide tetanus toxoid conjugate vaccine
  • meningococcal A C Y and W-135 diphtheria conjugate vaccine
  • tetradecyl Sulfuric Acid
  • benzoyl peroxide, clindamycin phosphate, adapalene
  • ethylephedrine
  • actarit
  • pyrantel tartrate
  • tenofovir disoproxil fumarate or tenofovir DF
  • melitracen
  • amitriptylinoxide(Phase 4 Clinical Trials)
  • threonine
  • ditiocarb zinc
  • epicriptine
  • levallorphan
  • kinetin
  • laurocapram
  • pentagastrin
  • parthenolide
  • nicoboxil
  • protionamide
  • prulifloxacin
  • proscillaridin
  • tizanidine and rofecoxib
  • tolnaftate, gentamicin, chinoform and betamethasone valerate
  • pine bark extract
  • pipenzolate methylbromide
  • bephenium hydroxynaphthoate
  • niclosamide
  • pyrvinium
  • pipenzolate methylbromide/phenobarbitone
  • piracetam/ginkgo biloba/vinpocetine
  • benzyl benzoate/disulfiram
  • benzyl benzoate
  • loperamide/simethicone
  • piroctone olamine
  • sodium fusidate
  • piroxicam topical/capsaicin/menthol/methyl salicylate
  • sodium metabisulfite
  • sodium lauryl sulfate
  • taspoglutide
  • glyclopyramide
  • tolnaftate, gentamicin, iodochlorohydroxyquinoline, chlorocresol, betamethasone valerate
  • serratiopeptidase
  • sodium antimony gluconate
  • triamterene / benzthiazide
  • tribenoside / lidocaine
  • triclocarban
  • triprolidine/dextromethorphan  
  • vitamins/minerals/omega-3 Fatty acids
  • soyabean oil
  • sucralfate/oxethazaine
  • sucralfate/tinidazole/povidone iodine
  • sodium cromoglycate
  • aloe vera/liquid paraffin/white soft paraffin
  • aloe vera/jojoba oil/vitamin E
  • allantoin/triclosan/vitamin e/zinc oxide
  • alpha-Lipoic acid/minerals/multivitamins
  • alprazolam/paracetamol
  • alprazolam/melatonin
  • azithromycin/ambroxol
  • atorvastatin/clopidogrel/aspirin
  • aceclofenac, paracetamol and serratiopeptidase
  • alfacalcidol, vitamin B-complex, minerals and antioxidants
  • alpha- lipoic acid, vitamin b complex and vitamin c
  • alpha-galactosidase and simethicone
  • alpha-galactosidase, amylase, proteases, lipase and lactase
  • amikacin and cefepime
  • aminophylline, ephedrine and phenobarbitone
  • artesunate, sulphadoxine and pyrimethamine
  • finasteride/tamsulosin
  • flavoxate/ofloxacin
  • fenofibrate/metformin
  • lignocaine, hydrocortisone topical and allantoin
  • linoleic acid and sodium lactate
  • troxerutin
  • meclizine/nicotinic acid
  • mecobalamin/ginkgo Biloba
  • spirulina
  • loperamide and furazolidone
  • ketoconazole/cetrimide
  • ketoconazole/zinc pyrithione
  • lercanidipine/atenolol
  • levocetirizine/montelukast/ambroxol
  • levarterenol
  • levocetirizine/phenylpropanolamine 
  • indapamide/amlodipine
  • itopride/methyl polysiloxane
  • mebendazole/levamisole
  • eberconazole/mometasone
  • gliclazide/metformin/pioglitazone
  • fluconazole/tinidazole
  • haemocoagulase
  • halometasone
  • hesperidin
  • imipramine/chlordiazepoxide
  • idebenone / l-arginine / zinc sulphate/selenium/proanthocyanidin
  • mecobalamin and piracetam
  • mesterolone
  • mosapride and pantoprazole
  • atorvastatin, co enzyme q10, vitamin e, zinc, and selenium
  • azithromycin and benzalkonium chloride
  • beta carotene, vitamin c, vitamin e, minerals, lutein, eicosapentaenoic acid, docosahexenoic acid and vit b12
  • alpha-galactosidase
  • aloe vera gel/vitamin e/lactic acid
  • aloe vera gel/jojoba/vitamin e/glycerine
  • famotidine and domperidone
  • faropenem medoxomil
  • nedosiran
  • fluconazole/ornidazole/azithromycin
  • ebastine/montelukast
  • eberconazole
  • dienogest/estradiol valerate
  • ambroxol/salbutamol
  • benzoic acid/salicylic acid/ichthammol/ triamcinolone acetonide
  • desloratadine/ambroxol
  • dexibuprofen/paracetamol
  • atorvastatin/ramipril
  • diastase
  • diastase and simethicone
  • diazepam and propranolol
  • dexrabeprazole / domperidone
  • dexrabeprazole
  • dexketoprofen /paracetamol
  • beta carotene/vitamin C/minerals
  • aloe vera gel/urea
  • aloe vera gel/glycerine
  • alpha-lipoic acid/benfotiamine/chromium/folic acid/mecobalamin / vit b6
  • alprazolam/propranolol
  • alprazolam /sertraline
  • ibuprofen/dextropropoxyphene
  • ambroxol/cetirizine/phenylephrine/ guaiphenesin/menthol
  • dextropropoxyphene/dexchlorpheniramine maleate/bromhexine
  • promegestone
  • batroxobin
  • bencyclane
  • benfluorex
  • acetylpheneturide
  • abarelix
  • abetimus
  • naftidrofuryl
  • nalorphine
  • oxiracetam
  • letosteine
  • lafutidine
  • leuprorelin
  • levodropropizine
  • glutaral
  • losartan/ramipril
  • gallopamil
  • lanatoside c
  • lauromacrogol
  • gestodene
  • aceclofenac/methyl salicylate/menthol/linseed oil/capsaicin
  • aceclofenac/paracetamol/tizanidine
  • alginic acid/magaldrate/simethicone
  • aceclofenac/paracetamol
  • aceclofenac/rabeprazole
  • alginic acid
  • pantoprazole and domperidone
  • urokinase
  • rimiterol
  • olanzapine/fluoxetine
  • normethadone/hydroxyephedrine
  • myrtol
  • moxonidine
  • propylhexedrine
  • sodium hypochlorite solution
  • sodium chloride/sodium citrate
  • Hepatitis B Vaccine (Recombinant [Adjuvanted])
  • Hepatitis B Vaccine (Recombinant)
  • aceclofenac and serratiopeptidase
  • levosulpiride
  • niaprazine
  • tromantadine
  • trimetazidine
  • vinburnine
  • mizoribine
  • molgramostim
  • mosapride
  • eugenol
  • tolperisone
  • etamsylate
  • etynodiol
  • mizolastine
  • metenolone
  • reproterol
  • rebamipide
  • mephenoxalone
  • metandienone
  • furosemide/spironolactone
  • hydroxycarbamide
  • tenonitrozole
  • fenoverine
  • fenquizone
  • tiapride
  • tibolone
  • furazolidone
  • furosemide & amiloride
  • fosfestrol
  • fluclorolone
  • flubendazole
  • tertatolol
  • tetracosactide
  • tetryzoline
  • tolciclate
  • trapidil
  • troxipide
  • temoporfin
  • telbivudine
  • teprenone
  • hexamidine
  • mebhydrolin
  • mepartricin
  • fencamfamin
  • medazepam
  • theodrenaline
  • thiamazole
  • thiocolchicoside
  • psilocybin
  • veralipride
  • pyritinol
  • opipramol
  • oprelvekin
  • betamethasone + gentamicin
  • betamethasone + neomycin
  • betamethasone + salicylic acid
  • oxedrine
  • bopindolol
  • orgotein (investigational)
  • oxaceprol
  • ormeloxifene
  • bevantolol
  • bifemelane
  • clebopride
  • demoxytocin
  • cicletanine
  • cefsulodin
  • chlortalidon
  • sisomicin
  • somatrem
  • carbazochrome
  • caroverine
  • cathine
  • ipriflavone
  • isepamicin
  • silymarin
  • simethicone
  • sermorelin
  • diloxanide
  • dimethindene
  • diosmin/hesperidin
  • calamine
  • canrenone
  • captodiame
  • imidapril
  • cefetamet
  • cefodizime
  • cefoperazone + sulbactam
  • ivermectin + albendazole
  • serrapeptase
  • bromisoval
  • beraprost
  • pridinol
  • proglumide
  • bamipine
  • barnidipine
  • bamifylline
  • benzbromarone
  • betamethasone/fusidic acid
  • para-chlorophenol
  • pantethine
  • nomifensine
  • pemoline
  • parnaparin
  • pentolinium
  • nialamide
  • novobiocin
  • nicergoline
  • octocrylene
  • octisalate
  • oftasceine
  • oxolamine
  • oxyphencyclimine
  • penfluridol
  • pentoxyverine
  • phenoxymethylpenicillin
  • picloxydine
  • pilsicainide hydrochloride
  • piperazine
  • pirarubicin
  • policresulen
  • prifinium bromide
  • prethcamide
  • pristinamycin
  • pirenzepine
  • piribedil
  • pimethixene
  • pargyline
  • phosphatidyl choline
  • phthalylsulfathiazole
  • phytomenadione
  • pranlukast
  • pinazepam
  • oxyphenonium
  • noxytiolin
  • periciazine
  • pethidine
  • phenindamine
  • histidine
  • isoleucine
  • proline
  • lauric acid
  • lymecycline
  • hypromellose
  • abiraterone acetate and niraparib
  • ichthammol
  • levamisole
  • naftazone
  • nefopam
  • oxprenolol
  • oxybuprocaine
  • elranatamab-bcmm
  • lapyrium
  • isoaminile
  • iotrolan
  • mazindol
  • masoprocol
  • lypressin
  • meradimate
  • molsidomine
  • monobenzone
  • mequinol/gluconolactone/ lactobionic acid/ arbutin
  • medifoxamine
  • mebutamate
  • metergoline
  • methantheline
  • methdilazine
  • metocurine
  • micronomicin
  • metaraminol
  • mephenesin
  • menadione
  • medrysone
  • metixene
  • levobetaxolol
  • guaiacol glycerol ether
  • eucalyptol
  • sodium tetradecyl sulfate
  • sugammadex
  • carbetocin
  • certoparin
  • chlorcyclizine/pseudoephedrine
  • cephapirin
  • indecainide
  • iobitridol
  • iomeprol
  • chlorphenesin
  • msud analog
  • msud maxamum
  • iceland moss
  • glutethimide
  • hexachlorophene
  • haloprogin
  • deferoxamine
  • ethchlorvynol
  • dexpanthenol topical
  • etilefrine
  • deslanoside
  • carbocromen
  • diazolidinylurea
  • dibenzepin
  • etofamide
  • guanoxan
  • halazepam
  • guanadrel sulfate
  • dapiprazole
  • soapwort
  • debrisoquine
  • l-tryptophan
  • chlormerodrin
  • chlorquinaldol
  • cetrimonium
  • carbocisteine
  • chlorcyclizine/codeine
  • technetium Tc-99m tetrofosmin
  • technetium Tc-99m disofenin
  • technetium Tc-99m gluceptate
  • technetium Tc-99m labeled red blood cells
  • amylmetacresol/dextromethorphan hydrobromide
  • anileridine phosphate
  • pyrethrins
  • pyrantel pamoate
  • quinagolide
  • spiramycin
  • standard hyperkalemic cardioplegia solution
  • technetium tc-99m mertiatide
  • technetium tc-99m medronate
  • bemotrizinol / bisoctrizole
  • benfotiamine
  • bemotrizinol + titanium dioxide + zinc oxide
  • technetium Tc-99m oxidronate
  • technetium Tc-99m pentetate
  • technetium Tc-99m pyrophosphate
  • benziodarone
  • octinoxate/bisoctrizole
  • bicisate dihydrochloride
  • technetium Tc-99m bicisate
  • norelgestromin/ethinyl estradiol
  • norgestimate/ethinyl estradiol
  • ximelagatran (investigational)
  • xamoterol
  • trioxsalen
  • poly-urea urethane
  • rilmenidine
  • pemirolast
  • oxitriptan
  • beclomethasone, intranasal
  • thimerosal
  • camphor gel
  • camphor
  • mumps virus vaccine, live
  • rubella virus vaccine, live
  • aluminum chloride (dental)
  • alum irrigation
  • framycetin, phenylephrine, and gramicidin
  • ombitasvir, paritaprevir, ritonavir, and dasabuvir
  • olipudase alfa
  • etonogestrel/ethinyl estradiol
  • mycophenolate
  • fluoroestradiol F 18
  • donor organ cardioplegia solution
  • fluciclovine F 18
  • fusidic acid (ophthalmic)
  • fusidic acid and hydrocortisone
  • framycetin, dexamethasone, and gramicidin
  • fludeoxyglucose F-18
  • fluorouracil/salicylic acid
  • indium In-111 oxyquinoline
  • indium In-111 pentetreotide
  • indium In-111 capromab pendetide
  • lusutrombopag
  • mitomycin (ophthalmic)
  • mifepristone and misoprostol
  • minoxidil (systemic)
  • methyl aminolevulinate (topical)
  • methyl folate, methylcobalamin, and acetylcysteine
  • ciclesonide/formoterol/tiotropium
  • nedocromil (Oral Inhalation)
  • batefenterol (Investigational)
  • neostigmine and glycopyrrolate
  • nepafenac ophthalmic
  • netupitant/palonosetron
  • meperidine and promethazine
  • mepivacaine and levonordefrin
  • maltodextrin
  • medical cannabis
  • medium chain triglycerides
  • mometasone/glycopyrrolate (glycopyrronium)/ indacaterol
  • moxifloxacin ophthalmic
  • neomycin/fluocinolone
  • nadroparin
  • iodine I-125 iothalamate
  • amikacin liposome (oral inhalation)
  • bupivacaine liposome
  • natamycin
  • lopinavir and ritonavir
  • lysine
  • macitentan and tadalafil
  • mitomycin pyelocalyceal
  • moclobemide
  • mometasone and indacaterol
  • efinaconazole
  • blue-green algae
  • indocyanine green
  • follitropin beta
  • lumasiran
  • glycerin/lidocaine
  • edrophonium/atropine
  • indigo carmine
  • lutropin alfa
  • instant glucose/intravenous dextrose
  • iobenguane I-123
  • ixekizumab
  • isosulfan blue dye
  • levofloxacin ophthalmic
  • levonorgestrel oral/ferrous bisglycinate/ ethinylestradiol
  • ethinyl estradiol/levonorgestrel transdermal
  • hydroquinone
  • hydroxypropyl methylcellulose
  • icodextrin
  • lipid emulsion (soybean, medium-chain triglyceride, olive, and fish oils; [SMOF])
  • iodinated I 125 albumin
  • iodinated I 131 albumin
  • lipid emulsion (plant oil-based)
  • levonorgestrel intrauterine
  • levonorgestrel/ethinyl estradiol
  • lactic acid and sodium-PCA
  • lactated Ringer solution
  • ketotifen (systemic)
  • lanolin
  • leuprolide and norethindrone
  • levodopa and benserazide
  • gonadorelin acetate
  • hemodialysis solutions
  • nirsevimab
  • gentian violet
  • gallium ga-68 dotatate
  • fusidic acid and betamethasone
  • gallium citrate Ga-67
  • gadopentetate dimeglumine
  • gadofosveset
  • follitropin delta
  • follitropin alfa and lutropin alfa
  • follitropin alfa
  • rocatinlimab
  • grass pollens allergen extract
  • flotufolastat F18
  • fluorescein ophthalmic
  • barium
  • balanced salt solution
  • air polymer type A intrauterine device
  • clodronate
  • bentoquatam
  • clobetasone
  • alfacalcidol
  • citric acid/glucono-delta-lactone/magnesium carbonate
  • benzoin
  • desirudin
  • immune globulin IV (IGIV)
  • dequalinium
  • pseudoephedrine/desloratadine
  • clofedanol
  • cyproterone and ethinyl estradiol
  • dextranomer and hyaluronic acid or derivatives
  • diatrizoate meglumine and diatrizoate sodium
  • glucosamine sulfate, chondroitin sulfate and Msm
  • squill
  • gotu kola
  • blessed thistle
  • bitter melon
  • apraclonidine
  • chlophedianol/dexbrompheniramine/pseudoephedrine
  • wild jujube
  • chitosan
  • cilazapril/hydrochlorothiazide
  • dexbrompheniramine and phenylephrine
  • diethylene triamine penta-acetic acid
  • dexchlorpheniramine and pseudoephedrine
  • lily of the valley
  • diflucortolone
  • corydalis
  • lemon balm
  • MSM
  • calcium polystyrene sulfonate
  • caprylidene
  • peppermint oil
  • efavirenz/lamivudine/tenofovir DF
  • emtricitabine/tenofovir DF /efavirenz
  • dutasteride/tamsulosin
  • milk thistle
  • centaury
  • horseweed
  • lycopus
  • agrimony
  • alfalfa
  • kava
  • cetrorelix
  • cetylpyridinium
  • chlophedianol and dexbrompheniramine
  • betahistine
  • choline C-11
  • boric acid vaginal suppository
  • aluminum acetate
  • aluminum chloride hexahydrate
  • 14-C urea breath test
  • absorbable collagen
  • valoctocogene roxaparvovec-rvox
  • amlodipine and celecoxib
  • aspirin and omeprazole
  • azilsartan and chlorthalidone
  • landiolol (Pending FDA approval)
  • isosorbide dinitrate/hydralazine
  • losartan/hydrochorothiazide
  • udenafil
  • dextromethorphan/quinidine
  • onasemnogene abeparvovec
  • orphenadrine/aspirin/caffeine
  • trace elements
  • sodium phenylbutyrate/ taurursodiol
  • fish oil triglycerides
  • infant formula
  • glutamine
  • chloroquine phosphate
  • afatinib
  • quinidine gluconate
  • methylergonovine
  • prothrombin complex concentrate, human
  • BCG intravesical live
  • capivasertib
  • cedazuridine
  • carbonyl iron
  • iron dextran complex
  • lovotibeglogene autotemcel (FDA Approval Pending)
  • sodium benzoate/sodium phenylacetate
  • mineral oil otic
  • zolmitriptan transdermal
  • midazolam intranasal
  • fosinopril/hydrochlorothiazide
  • caplacizumab
  • arginine
  • sodium phenylbutyrate
  • meloxicam/rizatriptan
  • manganese
  • acetaminophen/pamabrom/pyridoxine
  • varicella zoster immune globulin, human
  • amitriptyline/perphenazine
  • narsoplimab (Pending FDA Approval)
  • amlodipine/perindopril
  • imiglucerase
  • canagliflozin/metformin
  • tafamidis meglumine
  • somatrogon-ghla
  • glimepiride/rosiglitazone
  • becaplermin
  • lithium
  • loxapine inhaled
  • nicotine transdermal
  • tixagevimab and cilgavimab (Investigational)
  • muromonab CD3
  • ansuvimab
  • coal tar bath products
  • fibrin sealant
  • arimoclomol (FDA Approval Pending)
  • varenicline intranasal
  • aducanumab
  • oxycodone/naloxone
  • ritlecitinib
  • sodium polystyrene sulfonate
  • calcipotriene/betamethasone
  • calcium hydroxylapatite
  • cantharidin topical
  • doxepin cream
  • clocortolone
  • formaldehyde topical
  • sodium sulfide topical
  • collagenase
  • selegiline transdermal
  • foscarbidopa/foslevodopa (FDA approval pending)
  • saxagliptin/metformin
  • linagliptin/metformin
  • linzagolix (FDA approval pending)
  • efgartigimod/hyaluronidase SC
  • elamipretide (Pending FDA approval)
  • rozanolixizumab
  • diazoxide
  • glimepiride/pioglitazone
  • cipaglucosidase alfa
  • dihydroergotamine intranasal
  • delandistrogene moxeparvovec
  • beremagene geperpavec
  • hyaluronic acid and derivatives
  • hyaluronic acid, non-animal stabilized
  • eplontersen (FDA Approval Pending)
  • nitric oxide gas
  • sodium phenylbutyrate and taurursodiol
  • treprostinil SC
  • viltolarsen
  • albuterol/ipratropium
  • budesonide inhaled
  • budesonide rectal
  • palovarotene
  • sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycol
  • amino acids mixture
  • aminobenzoate potassium
  • elivaldogene autotemcel
  • naproxen and sumatriptan
  • sumatriptan intranasal
  • alglucerase
  • metformin/rosiglitazone
  • ertugliflozin/metformin
  • elosulfase alfa
  • calcium carbonate/magnesium hydroxide
  • starch suppository
  • abicipar pegol (FDA Approval Pending)
  • riboflavin 5′-phosphate ophthalmic
  • povidone ophthalmic
  • glycerin oropharyngeal
  • dimethicone topical
  • menthol topical, dimethicone topical
  • pramoxine topical, menthol topical and dimethicone topical
  • phosphorated carbohydrate
  • brilliant blue G ophthalmic
  • brolucizumab intravitreal
  • purified water, ophthalmic
  • hydroxyethyl cellulose ophthalmic
  • ranibizumab intravitreal implant
  • sodium chloride hypertonic, ophthalmic 
  • cetirizine ophthalmic
  • phentolamine ophthalmic
  • ganciclovir ophthalmic
  • triamcinolone intravitreal
  • ocriplasmin intravitreal
  • atoltivimab/maftivimab/odesivimab
  • pegcetacoplan intravitreal
  • triamcinolone acetonide extended-release injectable suspension
  • tobramycin/loteprednol ophthalmic
  • 2-octyl cyanoacrylate
  • vitamins A & D topical
  • diphenhydramine/allantoin topical
  • pyrethrins/piperonyl butoxide
  • lodoxamide ophthalmic
  • obeticholic acid
  • fluocinolone intravitreal implant
  • sincalide
  • linaclotide
  • nedocromil ophthalmic
  • cysteamine ophthalmic
  • avacincaptad pegol intravitreal
  • azelastine ophthalmic
  • bacitracin ophthalmic
  • propylene glycol ophthalmic
  • rimexolone ophthalmic
  • metoclopramide intranasal
  • mirikizumab
  • netarsudil ophthalmic
  • cenegermin
  • dexamethasone ophthalmic insert
  • prednisolone ophthalmic
  • phenylephrine and cocoa butter rectal
  • phenylephrine and witch hazel topical
  • phenylephrine, pramoxine, glycerin and petrolatum rectal
  • bisacodyl rectal
  • aluminum hydroxide/magnesium carbonate
  • aluminum hydroxide/magnesium hydroxide
  • hyoscyamine spray
  • methenamine/methylene blue/ hyoscyamine/ sodium phosphate monobasic/ phenyl salicylate
  • phenylephrine
  • chlorophyll
  • castor oil
  • cholic acid
  • phenol oropharyngeal
  • articaine/epinephrine
  • antithymocyte globulin equine
  • aluminum hydroxide/magnesium trisilicate
  • methenamine/hyoscyamine
  • hydrocortisone topical/pramoxine topical 
  • sodium fluoride topical
  • mesna
  • C1 esterase inhibitor recombinant
  • menthol and pectin
  • menthol oropharyngeal
  • pectin oropharyngeal
  • gepirone
  • Goldenseal
  • polyethylene glycol and electrolytes
  • polyethylene glycol/electrolytes/sodium ascorbate/ascorbic acid
  • brompheniramine/pseudoephedrine/dextromethorphan
  • brompheniramine phenylephrine
  • acetaminophen/doxylamine/phenylephrine
  • doxylamine/acetaminophen/pseudoephedrine/dextromethorphan
  • acetaminophen/doxylamine/dextromethorphan
  • acetaminophen/doxylamine/dextromethorphan/phenylephrine
  • eslicarbazepine
  • fluticasone and salmeterol
  • codeine, acetaminophen, butalbital and caffeine
  • codeine, chlorpheniramine and phenylephrine
  • iodine
  • povidone iodine
  • butalbital/aspirin/caffeine/codeine
  • polyethylene glycol 400/propylene glycol ophthalmic 
  • pegvaliase
  • amivantamab
  • iopamidol
  • codeine and pseudoephedrine
  • emtricitabine, rilpivirine, tenofovir DF
  • penicillin G aqueous
  • miconazole topical
  • miconazole vaginal
  • ciprofloxacin inhaled (Pending FDA approval)
  • ceftazidime/avibactam
  • ceftolozane/​tazobactam
  • aztreonam inhalation
  • amphotericin B cholesteryl sulfate
  • miconazole oral
  • elvitegravir/cobicistat/emtricitabine/tenofovir DF
  • isavuconazonium sulfate
  • dapivirine intravaginal (FDA Approval Pending)
  • lamivudine/raltegravir
  • codeine/triprolidine/pseudoephedrine
  • cadexomer iodine
  • brompheniramine/pseudoephedrine
  • codeine/acetaminophen
  • codeine/guaifenesin
  • beclomethasone inhaled
  • epoetin beta/methoxy polyethylene glycol
  • voreloxin(Orphan Drug)
  • rociletinib
  • pitcher plant
  • phosphatidylserine
  • telotristat ethyl
  • copper CU 64 dotatate
  • urea topical
  • exenatide subdermal implant
  • asenapine transdermal
  • ethiodized oil
  • urea oral
  • miglustat
  • acalisib(Investigational)
  • acetophenazine
  • guggul
  • aceneuramic acid
  • mestranol/norethindrone
  • reishi
  • lactitol
  • vonoprazan fumarate
  • motherwort
  • silver nitrate
  • salicylic acid/sulfur shampoo
  • salicylic acid topical
  • ketorolac ophthalmic
  • ketoconazole topical
  • Japanese encephalitis virus vaccine
  • dibucaine topical ointment
  • ketorolac intranasal
  • ketorolac/phenylephrine ophthalmic
  • rotavirus oral vaccine, live
  • guarana
  • hops
  • krill oil
  • salicylic acid/coal tar shampoo
  • sufentanil SL
  • pancrelipase
  • passion flower
  • pepdite one plus
  • nivolumab and relatlimab
  • relatlimab (Pending FDA Approval)
  • benzalkonium chloride/benzocaine
  • ketotifen, drug-eluting contact lens
  • calcitriol topical
  • oxymetazoline topical
  • alclometasone topical
  • capsaicin topical
  • diclofenac/misoprostol
  • diclofenac ophthalmic
  • diclofenac topical
  • pramoxine/calamine topical
  • veverimer
  • tolazoline
  • olopatadine ophthalmic
  • lutetium lu 177-dota-tate
  • lutetium lu 177 vipivotide tetraxetan
  • strontium 89 chloride
  • interferon alfa n3
  • lutetium Lu 177- Diethylenetriamine Pentaacetic acid-omburtamab (FDA Approval Pending)
  • samarium sm 153 lexidronam
  • cytomegalovirus immune globulin (CMV IG)
  • antithymocyte globulin rabbit
  • inolimomab (Pending FDA Approval)
  • olopatadine intranasal
  • olopatadine intranasal/​mometasone, intranasal
  • benzocaine/butamben/tetracaine topical
  • antipyrine/benzocaine/phenylephrine
  • dyclonine/menthol
  • surufatinib
  • fruquintinib
  • dostarlimab
  • hepatitis B immune globulin (HBIG)
  • remestemcel-L
  • benzocaine/menthol oropharyngeal
  • interferon beta 1b
  • tetracaine/oxymetazoline intranasal
  • benzocaine oropharyngeal
  • benzalkonium chloride/menthol/petrolatum topical
  • inamrinone
  • alpha 1 proteinase inhibitor
  • potassium bicarbonate/potassium citrate
  • potassium phosphate/sodium acid phosphate
  • asparaginase Erwinia chrysanthemi recombinant
  • motixafortide
  • pegloticase
  • etesevimab
  • Rho(D) immune globulin
  • tetanus immune globulin (TIG)
  • reltecimod (pending FDA approval)
  • avasopasem
  • trimethoprim/polymyxin B ophthalmic
  • naphazoline ophthalmic
  • sulfacetamide topical
  • sirolimus intravitreal (pending FDA approval)
  • sirolimus protein bound
  • sirolimus topical
  • glycopyrronium tosylate topical
  • sofpironium
  • olmesartan, amlodipine and hydrochlorothiazide
  • dovitinib (Pending FDA Approval)
  • epinephrine inhaled
  • quizartinib (Pending FDA Approval)
  • ranibizumab intravitreal injection
  • sodium hyaluronate
  • bacitracin and lidocaine topical
  • brimonidine topical
  • benzoyl peroxide and tretinoin topical
  • talquetamab
  • betrixaban
  • acetaminophen/caffeine/pyrilamine
  • fentanyl transmucosal
  • bacitracin topical
  • buprenorphine,long-acting injection
  • buprenorphine buccal
  • nalmefene intranasal
  • sulbactam/durlobactam
  • metronidazole topical 
  • daratumumab/hyaluronidase
  • glofitamab
  • rituximab-hyaluronidase
  • drospirenone/ethinyl estradiol/levomefolate
  • loncastuximab tesirine
  • ingenol mebutate topical
  • momelotinib
  • trastuzumab/deruxtecan
  • trastuzumab/hyaluronidase
  • trastuzumab duocarmazine
  • lifileucel
  • umbralisib
  • eflornithine/sulindac
  • cytarabine/daunorubicin liposomal
  • doxorubicin liposomal
  • epcoritamab
  • lanadelumab  
  • esomeprazole/naproxen 
  • terbinafine topical
  • ravulizumab
  • clotrimazole topical
  • choline magnesium trisalicylate
  • tacrolimus ointment
  • mechlorethamine topical
  • donislecel
  • pozelimab (Pending FDA Approval)
  • human rabies immune globulin (HRIG)
  • melphalan flufenamide
  • sintilimab (Pending FDA Approval)
  • oportuzumab monatox (Pending FDA Approval)
  • sotorasib
  • irinotecan liposomal
  • sulfur topical
  • silver sulfadiazine
  • capsaicin transdermal
  • sutimlimab
  • tretinoin topical
  • acetaminophen rectal
  • menthol topical
  • naftifine
  • oatmeal, colloidal topical
  • oxiconazole
  • methylsalicylate/menthol topical
  • C1 inhibitor human
  • lifitegrast ophthalmic
  • prednisolone/sulfacetamide ophthalmic
  • mannitol inhalation
  • ofloxacin otic
  • petrolatum & mineral oil topical
  • clascoterone topical
  • gefapixant (Pending FDA Approval)
  • colesevelam
  • technetium Tc 99m succimer
  • nebivolol/valsartan
  • ciprofloxacin/fluocinolone acetonide, otic
  • finafloxacin otic
  • magnesium hydroxide/mineral oil
  • phenylephrine/mineral oil/petrolatum rectal
  • carbamide peroxide oral
  • atropine ophthalmic
  • sodium sulfacetamide/sulfur
  • sulfacetamide ophthalmic
  • lucinactant
  • benzonatate
  • besifloxacin ophthalmic
  • benzhydrocodone/acetaminophen
  • beractant
  • trimagnesium citrate anhydrous
  • vitamin b2
  • carbamide peroxide otic
  • mineral oil topical
  • ethyl alcohol intranasal
  • boric acid/alcohol otic
  • absorbable gelatin compressed sponge, USP
  • absorbable gelatin sponge, USP
  • vincristine liposomal
  • technetium Tc 99m albumin aggregated injection
  • metaproterenol
  • budesonide inhaled/formoterol/glycopyrrolate inhaled
  • epinephrine racemic
  • umeclidinium bromide/vilanterol inhaled
  • indacaterol, inhaled/glycopyrrolate inhaled
  • betaine  
  • laronidase 
  • estrogens esterified/methyltestosterone            
  • cerliponase alfa
  • ertugliflozin/sitagliptin
  • hawthorn
  • shepherd’s purse
  • thiamine
  • naphazoline/glycerin ophthalmic
  • oxymetazoline ophthalmic
  • dorzolamide
  • dexamethasone intraocular
  • dexamethasone/ciprofloxacin
  • dexamethasone ophthalmic
  • metipranolol ophthalmic
  • timolol ophthalmic
  • boron
  • fezolinetant
  • pegunigalsidase alfa-iwxj
  • biotin
  • pantothenic acid
  • silicon
  • sodium acid phosphate
  • hypochlorous acid topical
  • methenamine/sodium acid phosphate
  • aviptadil 
  • bremelanotide
  • glucagon intranasal
  • metformin and repaglinide
  • bai ji
  • pau d’arco
  • juzentaihoto
  • mistletoe
  • quercetin
  • rosemary
  • sheng di huang
  • chasteberry
  • maitake
  • grapefruit
  • lentinan
  • juniper
  • nettle
  • parsley
  • rose hips
  • tongkat ali
  • horny goat weed
  • damiana
  • yohimbe
  • insulin NPH
  • aprocitentan
  • noni Juice
  • sodium iodide I-131
  • green tea
  • sea cucumber
  • wheat germ extract
  • fenofibrate micronized 
  • rogisen
  • danshen
  • lutein
  • witch hazel
  • dextroamphetamine transdermal
  • amphetamine/dextroamphetamine
  • hoodia
  • kolanut
  • boswellia
  • opuntia ficus indica
  • lavender
  • nadh
  • tea tree oil
  • metformin/sitagliptin 
  • dapagliflozin/ metformin/saxagliptin  
  • antihemophilic factor recombinant
  • inclisiran
  • bempedoic acid/ezetimibe
  • volanesorsen  
  • omega 3 carboxylic acids
  • pericyazine
  • levomepromazine (methotrimeprazine)
  • betaxolol ophthalmic
  • respiratory syncytial virus vaccine, adjuvanted
  • phenylephrine hydrochloride and tropicamide ophthalmic
  • alirocumab
  • neomycin/polymyxin B/gramicidin ophthalmic
  • factor IX
  • gentamicin topical
  • ansofaxine (Pending FDA Approval)
  • zuranolone
  • factor IX, recombinant
  • factor IX complex
  • factor XIII A-subunit, recombinant
  • factor X, human
  • mesalamine rectal
  • etrasimod
  • anti-inhibitor coagulant complex
  • factor IX, recombinant/albumin fusion protein
  • fibrinogen, human
  • aminocaproic acid
  • metyrosine
  • nonoxynol-9 vaginal
  • progesterone intravaginal gel
  • ipecac syrup
  • botulinum antitoxin, heptavalent
  • pentetate calcium trisodium
  • crotalidae polyvalent immune FAB (ovine)
  • dehydrated alcohol injection 
  • gold sodium thiomalate (Discontinued)
  • lactic acid/citric acid/potassium bitartrate vaginal
  • von Willebrand factor, recombinant
  • luspatercept
  • digoxin immune FAB (Antidote)
  • crotalidae immune FAB (equine)
  • magnesium (Antidote)
  • pyridoxine (Antidote)
  • edetate calcium disodium
  • albumin IV
  • nitroglycerin sublingual
  • obiltoxaximab
  • anthrax immune globulin
  • nitroglycerin topical
  • dextrose
  • nesiritide
  • estradiol vaginal
  • bazedoxifene/conjugated estrogens
  • botulism immune globulin iv
  • amoxicillin/omeprazole/rifabutin
  • synthetic human angiotensin II
  • nitroglycerin IV
  • nitroglycerin translingual
  • nitroprusside sodium
  • tetrahydrozoline/zinc sulfate/hypromellose ophthalmic
  • sodium citrate/citric acid
  • pemetrexate
  • methicillin
  • plasminogen 
  • acai
  • american ginseng
  • cordyceps
  • tramadol/acetaminophen
  • belladonna alkaloids/phenobarbital
  • erythromycin topical/benzoyl peroxide
  • glucosamine sulfate
  • panax ginseng (suppl/herb)
  • tolnaftate
  • sulopenem etzadroxil/probenecid
  • sulfur hexafluoride
  • sotrovimab
  • arbaclofen
  • rifampin/isoniazid
  • clindamycin /tretinoin topical
  • benzoyl peroxide/clindamycin topical
  • apremilast
  • antivenins, centuroides (scorpion)
  • bamlanivimab and etesevimab
  • vilobelimab
  • gadobenate
  • pentosan polysulfate sodium
  • methylsalicylate/menthol/camphor topical
  • antivenin, black widow spider
  • benzoyl peroxide and hydrocortisone
  • clindamycin topical
  • isometheptene, dichloralphenazone and acetaminophen
  • acetaminophen and phenyltoloxamine
  • erythromycin topical
  • erythromycin ophthalmic
  • alpha hydroxy acids, topical
  • buprenorphine transdermal
  • butalbital/acetaminophen/caffeine
  • buprenorphine/samidorphan
  • buprenorphine subdermal implant
  • celecoxib/tramadol
  • drospirenone/ethinyl estradiol
  • resorcinol/sulfur
  • eflornithine
  • rifampin/isoniazid/pyrazinamide
  • tofersen
  • devil’s claw
  • ticarcillin/clavulanate
  • atropine/pralidoxime
  • aprepitant
  • suramin
  • phenelzine 
  • artichoke
  • american dogwood
  • attapulgite
  • atlantic cedar
  • axalimogene filolisbac
  • sodium thiosulfate & sodium nitrite
  • ataluren
  • omidubicel-onlv
  • capsicum
  • ginger
  • cryoprecipitate
  • bictegravir/emtricitabine/tenofovir DF
  • emtricitabine/tenofovir DF
  • fo-ti
  • siberian ginseng
  • granulocytes
  • zinc substituted heme C
  • zinc trihydroxide
  • ashwagandha 
  • cat’s claw
  • glandular products
  • SAMe
  • shark cartilage
  • altovis
  • feverfew
  • horse chestnut
  • magnesium aspartate
  • octacosanol
  • pleurisy root
  • star anise
  • butterbur
  • elderberry
  • licorice (Suppl/herb)
  • aconite
  • pentetate zinc trisodium
  • menthol topical/zinc oxide topical
  • corn-starch/kaolin/zinc oxide topical
  • 5-hydroxytryptophan (5-htp)
  • butcher’s broom
  • articulin
  • bearberry
  • goldenrod
  • progesterone, natural
  • black cohosh
  • wild yam
  • cranberry
  • dong quai
  • phytoestrogens
  • norethindrone
  • false Unicorn Root
  • raspberry Leaf
  • asafoetida
  • turmeric
  • dehydroepiandrosterone (DHEA)
  • hyaluronan
  • aliskiren/amlodipine
  • octreotide (Antidote)
  • tranexamic acid injection
  • duocal
  • neocate infant formula
  • pediatric Eo28
  • aloe
  • red clover
  • propolis
  • androstenedione
  • heartsease
  • comfrey
  • bilberry
  • chamomile
  • eyebright
  • calendula
  • sage
  • yucca
  • polypody
  • odevixibat
  • vinpocetine
  • olanzapine/samidorphan
  • creatine
  • yerba mate
  • spesolimab
  • azficel-T
  • tiludronate
  • estetrol and drospirenone
  • pseudoephedrine/fexofenadine
  • lincomycin
  • neomycin oral
  • fluocinolone acetonide, otic
  • tretinoin/ hydroquinone/ fluocinolone
  • halobetasol topical
  • hydrocortisone/​iodoquinol
  • penicillin G procaine /penicillin G benzathine
  • hydrocortisone probutate topical
  • colistin/neomycin/hydrocortisone/thonzonium otic
  • ebola zaire vaccine
  • hepatitis a/​b vaccine
  • vibegron
  • lindane
  • nystatin topical
  • respiratory syncytial virus (RSV) vaccine
  • chikungunya vaccine, live
  • tenecteplase
  • reteplase
  • anthrax vaccine adsorbed, adjuvanted
  • meningococcal ABCWY pentavalent vaccine
  • eculizumab
  • cholestyramine
  • tinzaparin
  • taurolidine/​citrate/​heparin
  • protein C concentrate
  • antithrombin alfa
  • antithrombin III
  • multivitamins, vision
  • ibuprofen/​chlorpheniramine/​pseudoephedrine
  • acetaminophen/ibuprofen
  • ibuprofen/pseudoephedrine
  • paclitaxel protein-bound
  • acetic acid vaginal
  • acetic acid otic
  • hydrocodone/ ibuprofen
  • methyl salicylate / isopropanol/ citronellyl acetate/ citric acid
  • ibuprofen and phenylephrine
  • acetylcysteine (Antidote)
  • iron/​folic acid/​vitamin/​mineral
  • iobenguane I-131
  • dolutegravir/rilpivirine
  • chlorhexidine topical
  • chlorhexidine oral
  • thyroid desiccated
  • proparacaine ophthalmic
  • podophyllum resin
  • phendimetrazine
  • phenoxybenzamine
  • polidocanol
  • phentermine and topiramate
  • piflufolastat F18
  • piperacillin/tazobactam
  • prednisolone and gentamicin ophthalmic
  • promethazine and codeine
  • poractant alfa
  • protamine sulfate
  • aflibercept intravitreal
  • prednicarbate
  • promethazine/dextromethorphan
  • codeine, phenylephrine, and promethazine
  • potassium phosphate
  • glatiramer acetate
  • gentamicin (Ophthalmic)
  • leniolisib
  • rezafungin
  • fluorometholone
  • dalfampridine
  • hydrocortisone topical 
  • empagliflozin and linagliptin
  • triamcinolone topical
  • minocycline topical
  • minocycline dental
  • ketotifen ophthalmic
  • darunavir and cobicistat
  • lidocaine topical
  • neomycin/polymyxin B/bacitracin/lidocaine (OTC)
  • lidocaine/ hydrocortisone
  • lidocaine anesthetic
  • lidocaine ophthalmic
  • lidocaine/tetracaine
  • desonide
  • dabigatran
  • fexofenadine
  • fluoride
  • decitabine and cedazuridine
  • dasiglucagon
  • hydroxypropyl cellulose ophthalmic
  • epoetin alfa
  • ibritumomab tiuxetan
  • trimethobenzamide
  • dexamethasone/ tobramycin
  • tafasitamab
  • valacyclovir
  • mebendazole
  • levoleucovorin
  • flaxseed
  • germanium
  • glutathione
  • lycopene
  • pygeum
  • horseradish
  • ziv-aflibercept
  • micafungin
  • trofinetide
  • taliglucerase alfa
  • tildrakizumab
  • sulopenem (Pending FDA Approval)
  • thyrotropin alfa
  • birch
  • thrombin, topical
  • tivozanib
  • tafluprost
  • methohexital
  • urea and hydrocortisone
  • unoprostone ophthalmic
  • trihexyphenidyl
  • ezetimibe
  • evolocumab
  • trifluridine and tipiracil
  • methenamine
  • misoprostol
  • miltefosine
  • rimantadine
  • maralixibat
  • coenzyme Q10
  • chlorella
  • garlic
  • forskolin
  • zavegepant
  • menotropins
  • margetuximab
  • meprobamate
  • melarsoprol
  • evening primrose oil
  • lemongrass
  • molindone
  • fenugreek
  • phytosterols
  • red yeast rice
  • uridine triacetate
  • tropicamide
  • incobotulinumtoxinA
  • Grape Seed Extract
  • carbachol ophthalmic
  • cosyntropin
  • cyclopentolate and phenylephrine
  • carteolol ophthalmic
  • pentazocine/naloxone
  • pentazocine/acetaminophen
  • casimersen
  • carisoprodol, aspirin, and codeine
  • carisoprodol
  • carboprost tromethamine
  • flurandrenolide
  • brinzolamide/brimonidine
  • betamethasone topical
  • omaveloxolone
  • bardoxolone
  • allogeneic processed thymus tissue
  • fluocinolone topical
  • tacrolimus topical
  • ruxolitinib topical
  • pimecrolimus topical
  • sofosbuvir, velpatasvir and voxilaprevir
  • sofosbuvir/velpatasvir
  • mitotane
  • elbasvir/​grazoprevir
  • wheat dextrin
  • vanadium
  • iron/folic acid/vitamin/mineral
  • molybdenum
  • sparsentan
  • velmanase alfa-tycv
  • pegcetacoplan
  • ferrous sulfate
  • cyclosporine ophthalmic
  • ferric pyrophosphate
  • ammonium lactate
  • etelcalcetide
  • iodoquinol
  • sucroferric oxyhydroxide
  • doxercalciferol
amlodipine/telmisartan + 

aliskiren 

may increase the hyperkalemic effect of angiotensin receptor II blockers

amifostine 

may increase the hypotensive effect of blood pressure-lowering agents

cilazapril

may increase the toxic effect of angiotensin receptor II blockers

enalapril

may increase the toxic effect of angiotensin receptor II blockers

enalaprilat

may increase the toxic effect of angiotensin receptor II blockers

lisinopril

may increase the toxic effect of angiotensin receptor II blockers

perindopril

may increase the toxic effect of angiotensin receptor II blockers

obinutuzumab 

may enhance the serum concentration of CYP3A4 inhibitors

sirolimus 

may decrease the therapeutic effect of drugs affecting gallbladder function

ubrogepant 

may enhance the serum concentration of CYP3A4 inhibitors

lonafarnib 

may enhance the serum concentration of CYP3A4 inhibitors

bromeperidol 

may increase the hypotensive effect of blood pressure lowering agents

fexinidazole 

may enhance the serum concentration of CYP3A4 substrates

indoramin

may increase the hypotensive effect of calcium channel blockers

bunazosin (Not available in the United States)

may increase the hypotensive effect of calcium channel blockers

terazosin

may increase the hypotensive effect of calcium channel blockers

labetalol 

may increase the hypotensive effect of calcium channel blockers

prazosin

may increase the hypotensive effect of calcium channel blockers

perphenazine

may increase the hypotensive effect of blood pressure-lowering agents

pimavanserin

may increase the hypotensive effect of blood pressure-lowering agents

chlorpromazine

may increase the hypotensive effect of blood pressure-lowering agents

pipotiazine

may increase the hypotensive effect of blood pressure-lowering agents

haloperidol

may increase the hypotensive effect of blood pressure-lowering agents

primidone

may increase the hypotensive effect of blood pressure-lowering agents

phenobarbital

may increase the hypotensive effect of blood pressure-lowering agents

amobarbital

may increase the hypotensive effect of blood pressure-lowering agents

butalbital

may increase the hypotensive effect of blood pressure-lowering agents

butabarbital

may increase the hypotensive effect of blood pressure-lowering agents

calcium acetate

may decrease the therapeutic effect of calcium channel blockers

calcium carbonate

may decrease the therapeutic effect of calcium channel blockers

calcium chloride

may decrease the therapeutic effect of calcium channel blockers

calcium citrate

may decrease the therapeutic effect of calcium channel blockers

calcium glucoheptonate

may decrease the therapeutic effect of calcium channel blockers

efonidipine

may increase the hypotensive effect of blood pressure-lowering agents

ropivacaine

may increase the hypotensive effect of blood pressure-lowering agents

halothane

may increase the hypotensive effect of blood pressure-lowering agents

fimasartan

may increase the hypotensive effect of blood pressure-lowering agents

indoramin

may increase the hypotensive effect of blood pressure-lowering agents

ethacrynic acid

may increase the hypotensive effect of calcium channel blockers

bumetanide

may increase the hypotensive effect of calcium channel blockers

muzolimine

may increase the hypotensive effect of calcium channel blockers

tanshinone I

may increase the toxic effect of angiotensin receptor II blockers

rosmarinic acid

may increase the toxic effect of angiotensin receptor II blockers

caryophyllene

may increase the toxic effect of angiotensin receptor II blockers

ursolic acid

may increase the toxic effect of angiotensin receptor II blockers

cepharanthine

may increase the toxic effect of angiotensin receptor II blockers

eplerenone

may increase the hyperkalemic effect of angiotensin receptor II blockers

spironolactone

may increase the hyperkalemic effect of angiotensin receptor II blockers

triamterene

may increase the hyperkalemic effect of angiotensin receptor II blockers

amiloride

may increase the hyperkalemic effect of angiotensin receptor II blockers

canrenoic acid

may increase the hyperkalemic effect of angiotensin receptor II blockers

iloperidone

may increase the hypotensive effect of calcium channel blockers

iloprost

may increase the hypotensive effect of calcium channel blockers

selexipag

may increase the hypotensive effect of calcium channel blockers

ajmaline 

may increase the toxic effect of sulfonamides

ouabain

may increase the toxic effect of thiazide and thiazide like diuretics

digitoxin

may increase the toxic effect of thiazide and thiazide like diuretics

digoxin

may increase the toxic effect of thiazide and thiazide like diuretics

citalopram

may increase the hyponatremic effect of thiazide and thiazide-like diuretics

escitalopram

may increase the hyponatremic effect of thiazide and thiazide-like diuretics

flibanserin

may increase the hyponatremic effect of thiazide and thiazide-like diuretics

fluoxetine

may increase the hyponatremic effect of thiazide and thiazide-like diuretics

mianserin

may increase the hyponatremic effect of thiazide and thiazide-like diuretics

paricalcitol

may increase the hypercalcemic effect of thiazide and thiazide like diuretics

 

Dosage Forms & Strengths

Tablet

40mg/5mg

40mg/10mg

80mg/5mg

80mg/10mg

Hypertension 

Initial dose: Initiate with 40mg/5mg or 80mg/5mg orally every day. Do not exceed 80mg/10mg every day
Maximum dose: Telmisartan 80mg-amlodipine 10mg orally every day



Dose Adjustments

Hepatic impairment
Start with a lower dose of 2.5 mg amlodipine and increase the amount gradually

Renal impairment
Dosage adjustment is not required

 

Safety and efficacy not established

 

Refer adult dosing

Frequency defined:

10%

Peripheral edema (1-11%)

1-10%

Orthostatic hypotension (6%)

Back pain (2%)

Dizziness (3%)

Syncope (2%)

Post-marketing reports

asthenia, nausea, hypoglycemia, upper respiratory tract infection, jaundice, headache, coughing, fatigue, angioedema, gynecomastia, extrapyramidal syndrome

 

 

 

Contraindications

It is contraindicated in hypersensitivity and Patients with diabetes mellitus should not receive aliskiren in combination with them
Caution

  • Hypotension: It can lower blood pressure, leading to dizziness, light-headedness, and fainting. Patients should be cautious when standing up after sitting or lying down for an extended period.
  • Liver disease: It is metabolized in the liver, so it should be used cautiously in patients with liver disease.
  • Heart failure: It may worsen heart failure in some patients. It should be used cautiously in patients with heart failure or left ventricular dysfunction.
  • Pregnancy: It should not be used during pregnancy, as it can cause harm to the developing foetus. Women of childbearing age should use effective contraception while taking telmisartan

Pregnancy consideration:

It should not be used during pregnancy, as it can cause harm to the developing foetus

Lactation: Excretion of the drug in human breast milk is unknown

Pregnancy category:

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.

Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.

Category N: There is no data available for the drug under this category

Pharmacology

amlodipine is a dihydropyridine calcium channel blocker that blocks the influx of calcium ions into vascular smooth muscle cells, resulting in the relaxation of the blood vessels and a reduction in blood pressure. Amlodipine has a long duration of action and is typically given once daily telmisartan is an angiotensin II receptor blocker (ARB) that works by blocking the action of the hormone angiotensin II on its receptors in the blood vessels and other tissues. This results in the relaxation of the blood vessels and a reduction in blood pressure. Telmisartan has a long duration of action and is typically given once daily. In addition to its antihypertensive effects, telmisartan has been shown to have other beneficial effects, such as reducing inflammation and improving insulin sensitivity

Pharmacodynamics

amlodipine and telmisartan reduce blood pressure but do so through different mechanisms.amlodipine blocks calcium channels, while telmisartan works by blocking angiotensin II receptors

Pharmacokinetics

Absorption

telmisartan has a half-life of 24 hours, an onset of action of 1-2 hours, and a bioavailability of 42-58%, which is dose-dependent. amlodipine has a half-life of 30-50 hours, a bioavailability of 64-90%, and a Vd of 21 L/kg. Its peak plasma time is 6-12 hours

Distribution

Its volume of distribution (Vd) is 500 L, and its peak plasma time is 0.5-1 hour

Metabolism

telmisartan is highly protein-bound (>99.5%), and it is primarily metabolized in the liver to an inactive metabolite that is not metabolized by CYP enzymes. amlodipine is highly protein-bound (93-98%), and it is primarily metabolized in the liver by the P450 CYP3A4 enzyme

Elimination/excretion

telmisartan has a clearance of 800 mL/min, and it is mainly excreted in the faeces (97%). amlodipine has a clearance of 25 L/hr, and it is mainly excreted in the urine (70%)

Administration

amlodipine is available in tablet form in strengths ranging from 2.5 to 10 mg. The recommended starting dose of amlodipine is usually 5 mg once daily, and the maximum dose is 10 mg once daily. amlodipine can be taken with or without food, but it should be taken simultaneously every day telmisartan is available in tablet form in strengths ranging from 20 to 80 mg. The recommended starting dose of telmisartan is usually 20 mg once daily, and the maximum dose is 80 mg once daily.

Telmisartan can be taken with or without food, but it should be taken simultaneously every day It is essential to take these medications exactly as the healthcare provider prescribes, even if the patient is feeling well. Abruptly stopping these medications may result in a rebound increase in blood pressure, which may lead to serious health consequences. If a dose is missed, it should be taken as soon as possible unless it is almost time for the next dose, in which case the missed dose should be skipped, and the regular dosing schedule resumed

Patient information leaflet

Generic Name: amlodipine/telmisartan

Pronounced: [ am-LOE-de-peen-and-TEL-me-SAR-tan]

Why do we use amlodipine/telmisartan?

amlodipine is a calcium channel blocker used to treat hypertension and angina (chest pain). It is often prescribed in combination with other medications for the treatment of hypertension, such as angiotensin-converting enzyme (ACE) inhibitors, diuretics, and beta-blockers.

telmisartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. It is often used with other medications, such as diuretics and calcium channel blockers, to lower blood pressure. In addition to its blood pressure-lowering effects, telmisartan has been shown to have anti-inflammatory and antioxidant properties, and it may have additional benefits for patients with cardiovascular disease.

amlodipine/telmisartan

Brand Name :

Twynsta

Synonyms :

amlodipine/telmisartan

Class :

Angiotensin receptor II inhibitors, Calcium channel blockers




No data available for drug.

Dosage Forms & Strengths

Tablet

40mg/5mg

40mg/10mg

80mg/5mg

80mg/10mg

Hypertension 

Initial dose: Initiate with 40mg/5mg or 80mg/5mg orally every day. Do not exceed 80mg/10mg every day
Maximum dose: Telmisartan 80mg-amlodipine 10mg orally every day



Dose Adjustments

Hepatic impairment
Start with a lower dose of 2.5 mg amlodipine and increase the amount gradually

Renal impairment
Dosage adjustment is not required

Safety and efficacy not established

Refer adult dosing

DRUG INTERACTION

amlodipine/telmisartan

&

  • patisiran
  • imetelstat
  • phenylephrine ophthalmic
  • myoinositol
  • vasicinone
  • soda lime
  • fisetin
  • Reynoutria Japonica
  • Coco Monoethanolamide
  • Betadex
  • lithopone
  • cyperus rotundus
  • papaya juice
  • 1-naphthaleneacetic acid
  • Nordazepam
  • Glechoma hederacea
  • Alternanthera sessilis
  • nicofetamide
  • napthol asol
  • cocamidopropyl betaine
  • musa x paradisiaca
  • dicyclomine/mefenamic acid
  • Sorghum
  • Manganese citrate
  • tovorafenib
  • mefenamic acid/paracetamol
  • eschscholzia californica
  • canna indica root
  • tranexamic acid/mefenamic acid
  • dexverapamil
  • sitogluside
  • secalciferol
  • cefatrizine
  • Sedum Acre
  • Flurogestone
  • Fluocortin
  • Bifendate
  • piprozolin
  • aminacrine undecylate
  • ethylenediamine mandelate
  • pelubiprofen
  • hesperetin
  • butethamine
  • epitiostanol
  • androstenediol
  • Nitroxoline
  • Iocarmic acid
  • Capobenic acid
  • dordaviprone (investigational drug)
  • Vitexin
  • Friluglanstat (investigational drug)
  • scorias spongiosa
  • Luseogliflozin
  • indoxacarb
  • prademagene zamikeracel
  • fidanacogene elaparvovec-dzkt
  • albifylline
  • idanpramine
  • araneus diadematus
  • Sulfamazone
  • Lycosa tarantula
  • malotilate
  • Ethacizine
  • Namilumab
  • Latrunculin B
  • stachyose
  • platinic oxide
  • iopronic acid
  • calcium chloride / potassium chloride/lactic acid/ sodium chloride/sodium hydroxide/sodium lactate solution
  • citric acid/ sodium bicarbonate/ sodium carbonate anhydrous
  • vadadustat
  • permethrin medical grade cis/trans isomers 25/75
  • lutetium, isotope of mass 177
  • human normal immunoglobulin
  • sacrosidase
  • apadamtase alfa, recombinant
  • acetyl hexapeptide-8 amide
  • pemivibart (Investigational)
  • govorestat
  • Zanidatamab
  • sotatеrcеpt
  • MV 140 vaccine
  • leuprorelin implant
  • cinchocaine hydrochloride/fluocortolone hexanoate/fluocortolone pivalate
  • Beautyberry
  • risedronate/calcium/vitamin D3
  • rhubarb extract/senna leaf/sulphur purified/wood charcoal
  • boric acid/kaolin/methyl salicylate/peppermint oil/thymol
  • docosahexaenoic acid/eicospentaenoic acid
  • aluminium hydroxide/magnesium hydroxide/simethicone
  • gentamicin/hydrocortisone
  • succinylcholine
  • sinefungin
  • letibotulinumtoxinA
  • coal tar/coconut oil/salicylic acid
  • camphor/camphor oil white/capsicum oleoresin /menthol/methyl salicylate
  • thioglycolic acid
  • acetic acid auricular
  • roluperidone
  • hydrocortisone/crotamiton topical
  • nystatin/chlorhexidine
  • aluminium chloride hexahydrate
  • ketoprofen topical
  • Chlormethine
  • podophyllotoxin
  • urea/lactic acid
  • autologous chondrocytes implant
  • afelimomab
  • gepotidacin
  • fludroxycortide
  • fentanyl transdermal
  • erythromycin/zinc acetate
  • dibotermin alfa powder
  • desferrioxamine mesilate
  • choline salicylate/magnesium salicylate
  • castor oil/peru balsam/trypsin
  • betamethasone/dexchlorpheniramine maleate
  • benzalkonium chloride solution/cetrimide
  • barzolvolimab
  • ascorbic acid / calcium laevulinate / nicotinamide / calcium pantothenate / calcium chloride / riboflavine / pyridoxine hydrochloride / thiamine hydrochloride
  • argipressin
  • arachis oil refined/chlorobutanol hemihydrate
  • arachis oil/eucalyptol/nutmeg oil/terpineol
  • ammonium chloride/diphenhydramine hydrochloride/levomenthol
  • amino acid mixture d / calcium chloride dihydrate / glucose monohydrate / glycine / magnesium chloride hexahydrate / olive oil / potassium chloride / sodium acetate trihydrate / sodium glycerophosphate pentahydrate / soya-bean oil
  • biotin/colecalciferol/copper (ii)sulfate dried/ cyanocobalamine/ dl-alpha tocopherol acetate/dibasic calcium phosphate anhydrous/folic acid/iron (ii)sulfate dried/ lecithin/ magnesium sulfate dried/ nicotinamide/ pyridoxine hydrochloride/ riboflavin
  • ampicillin sodium / cloxacillin sodium
  • undecylenic acid, undecylenate salts, zincundecate
  • omeprazole/sodium bicarbonate
  • efgartigimod alfa/hyaluronidase
  • xylometazoline/ipratropium
  • cefepime and enmetazobactam
  • isotonic sodium chloride
  • bee venom allergen injection
  • fentanyl intranasal
  • alglucosidase alfa
  • triprolidine/pseudoephedrine
  • pegademase bovine
  • castor oil and peru balsam
  • camphor/eucalyptus oil/menthol
  • oxyquinoline/sodium lauryl sulfate
  • somatorelin
  • menotrophin injection
  • menadiol
  • hylan g-f 20
  • cefepime and taniborbactum
  • water avens
  • camphor/menthol
  • acoramidis
  • elafibranor
  • arrowroot
  • miconazole nitrate/hydrocortisone
  • vildagliptin/metformin
  • dobesilic acid
  • aroxybutynin and atomoxetine
  • hygromycin
  • linvoseltamab
  • nemolizumab
  • aceprometazine
  • limaprost
  • oxazolam
  • trimegestone
  • teceleukin
  • beauty berry
  • dinotefuran
  • imiprothrin
  • transfluthrin
  • thymalfasin
  • technetium Tc 99m tilmanocept
  • glepaglutide
  • marstacimab
  • pixantrone
  • Andiroba
  • arabinoxylan
  • arenaria rubra
  • etripamil
  • jequirity
  • jiaogulan
  • dusquetide
  • rolipram
  • tradipitant
  • sinfungin
  • diclofenac/omeprazole
  • brinzolamide and timolol maleate
  • wormseed
  • wormwood
  • wood sorrel
  • carmellose sodium
  • ibandronic acid
  • cinnarizine and dimenhydrinate
  • ursodeoxycholic acid
  • rhubarb extract/salicylic acid
  • butamirate citrate
  • fumitory
  • taheebo
  • uva ursi
  • vervain
  • coleus
  • coltsfoot
  • crampbark
  • plantain
  • potassium nitrate and silver nitrate
  • gelsemium
  • gentian
  • glucomannan
  • walnut
  • meadowsweet
  • midomafetamine
  • pennyroyal
  • periwinkle
  • betony
  • bitter orange
  • bladderwrack
  • bloodroot
  • emu oil
  • garcinia
  • yellow dock
  • burdock
  • dehydroepiandrosterone
  • aucubin
  • jasmone
  • resacetophenone
  • ecamsule ditriethanolamine
  • feclobuzone
  • fenoprop triethanolamine
  • verdyl acetate
  • caffeic acid
  • cyclamen aldehyde
  • dicetyldimonium chloride
  • wogonin
  • impacarzine
  • laurylpyridinium chloride
  • stepronin
  • matrine
  • sakuranin
  • cannabichromene
  • sandalore
  • sabinene
  • oxypaeoniflora
  • ethylhexyl pelargonate
  • acrylonitrile
  • allyl alcohol
  • dipalmitoylethyl hydroxyethylmonium methosulfate
  • butidrine
  • clothiapine
  • propanediol dicaprylate
  • buchu
  • undecanol
  • enilconazole
  • xymenynic acid
  • angelica
  • nizubaglustat
  • resomelagon
  • ulecaciclib
  • apple cider vinegar
  • bacopa
  • barley grass
  • dandelion
  • deer velvet
  • dolomite
  • bugleweed
  • bupleurum
  • glyceryltrinitrate
  • pociredir
  • asnuciclib
  • actalycabtagene autoleucel
  • butantan–dengue vaccine
  • travoprost/timolol
  • furosemide/potassium chloride
  • amylamine
  • jaborandi
  • patritumab deruxtecan
  • jackfruit
  • sterculia
  • ascorbigen
  • ashitaba
  • androstenetrione
  • andrachne
  • cosibelimab
  • racecadotril
  • neomycin/chlorhexidine
  • octocog alfa
  • cetrimide
  • ispaghula husk
  • polyhexanide
  • octenidine
  • polygeline
  • heparinoid
  • jewelweed
  • boldo
  • anizatrectinib
  • alpinia
  • henbane
  • cynanchum vincetoxicum root and sulfur
  • boditrectinib
  • izumerogant
  • zavondemstat
  • abuta
  • fadogia agrestis
  • fly agaric mushroom
  • meptazinol
  • methoxyflurane
  • tramadol/dexketoprofen
  • betaine/polyhexanide
  • filgotinib
  • inosine acedoben dimepranol
  • alverine citrate
  • hyoscine butylbromide
  • senna+ ispaghula
  • cabbage palm
  • cajeput oil
  • calanus oil
  • calamint
  • canada balsam
  • carnosine
  • alverine citrate/simeticone
  • dihydroartemisinin/piperaquine
  • mebeverine/ispaghula
  • calcipotriol
  • tacalcitol
  • triethyl citrate/ethyl linoleate
  • sodium dilauramidoglutamide lysine
  • fazamorexant
  • avibactam tomilopil and ceftibuten
  • drostanolone
  • tigilanol tiglate
  • isorhynchophylline
  • rhynchophylline
  • crisugabalin
  • epigallocatechin gallate
  • clomocycline
  • corynoxeine
  • isocorynoxeine
  • Culmerciclib
  • Neladenoson
  • ambrein
  • hexylcaine
  • phensuximide
  • resencatinib (investigational)
  • rolusafine
  • pumecitinib
  • arhalofenic acid
  • berdazimer sodium
  • benzquinamide
  • clidinium
  • sulfametopyrazine
  • fulzerasib (Investigational Drug)
  • rovadicitinib (Investigational Drug)
  • Upleganan (Investigational Drug)
  • menthyl ethylamido oxalate
  • quaternium-90 montmorillonite
  • unecritinib (investigational drug)
  • etohexadiol
  • guaiol
  • proximadiol
  • verdinexor
  • sofnobrutinib
  • talbutal
  • ethoxzolamide
  • propiomazine
  • enprofylline
  • phenmetrazine
  • merigolix
  • pralurbactam
  • neracorvir
  • vonifimod
  • apaziquone hydroquinone
  • darizmetinib
  • zandelisib
  • xininurad
  • ritivixibat
  • amiselimod phosphate (investigational drug)
  • emzeltrectinib (investigational drug)
  • ficonalkib
  • cinalukast
  • ulobetasol
  • candoxatril
  • nitrofural
  • acetyldigitoxin
  • bentiromide
  • dextrothyroxine
  • chlorotrianisene
  • remikiren
  • pipobroman
  • vidarabine
  • immune globulin intravenous, human-stwk
  • spermine
  • serine
  • N-acetyl glucosamine
  • valine
  • adenine
  • asparagine
  • citrulline
  • adinazolam
  • interferon alfacon-1
  • interferon alfa-n1
  • felypressin
  • birch triterpenes
  • pyridoxal phosphate
  • technetium Tc-99m arcitumomab
  • beta-alanine
  • dihomo-gamma-linolenic acid
  • urea/hydrocortisone
  • R21/Matrix-M vaccine
  • povidone-iodine (ophthalmic)
  • pheniramine
  • hydrocortisone rectal
  • chloroxylenol/pramoxine/zinc acetate
  • chloroxylenol/pramoxine
  • dextrose/sucrose/vitamin C/zinc sulphate
  • furazolidone/metronidazole/dicyclomine
  • ergocalciferol (vitamin D2)
  • benoxaprofen (discontinued)
  • teicoplanin
  • carbomer
  • chromic chloride / iron (ii) chloride tetrahydrate / potassium iodide / manganese chloride / sodium fluoride / sodium selenite pentahydrate / sodium molybdate dihydrate / zinc chloride/ cupric chloride
  • bufylline
  • lidocaine/prilocaine
  • opium tincture, squill oxymel
  • dibrompropamidine
  • metronidazole/tetracycline/bismuth subsalicylate
  • agnus- castus
  • velaglucerase alfa
  • alendronic acid / colecalciferol
  • bimatoprost / timolol
  • efbemalenograstim alfa
  • dried ferrous sulfate/folic acid
  • dried ferrous sulfate / sodium ascorbate
  • nirogacestat
  • soya-bean oil, medium-chain triglycerides
  • demeclocycline hydrochloride and triamcinolone acetonide
  • fusidic acid / hydrocortisone acetate
  • macrogol
  • storax, benzoin
  • nomegestrol acetate/estradiol
  • flumetasone pivalate/ clioquinol
  • berdazimer topical (Pending FDA Approval)
  • buflomedil
  • butobarbital
  • andexanet alfa
  • methoxypolyethylene glycol-epoetin beta
  • viscum abietis
  • pramoxine vaginal
  • bupivacaine implant
  • cromolyn sodium, inhaled
  • pneumococcal vaccine 20-valent
  • bimatoprost ophthalmic implant
  • tick-borne encephalitis vaccine
  • chloroprocaine ophthalmic
  • travoprost intraocular implant (Pending FDA approval)
  • typhoid polysaccharide vaccine
  • sodium phosphate rectal
  • human papillomavirus vaccine, nonavalent
  • peanut immunotherapy epicutaneous (FDA approval pending)
  • cromolyn sodium, intranasal
  • red blood cells(Blood component)
  • oral mucoadhesive
  • clindamycin vaginal
  • whole blood (Blood Component)
  • fibrinogen/thrombin
  • levothyroxine/liothyronine
  • ipratropium intranasal
  • metronidazole vaginal
  • cyamemazine
  • brinase
  • reviparin
  • ulinastatin
  • saruplase
  • acepromazine
  • emylcamate
  • methionine
  • amino acids and electrolytes in dextrose with calcium
  • slippery elm
  • camostat
  • hemoglobin crosfumaril
  • moperone
  • chlormidazole
  • brilaroxazine
  • palopegteriparatide
  • diazepam buccal
  • benegrastim (pending for FDA approval)
  • COVID-19 vaccine, adjuvanted-Novavax
  • vestronidase alfa-vjbk
  • tebipenem (Pending FDA Approval)
  • tislelizumab (Pending FDA Approval)
  • zolbetuximab (Pending FDA Approval)
  • zoliflodacin (pending FDA approval)
  • zibotentan and dapagliflozin
  • fluorine F18 DCFPyL
  • debamestrocel
  • givinostat
  • amubarvimab and romlusevimab(Pending FDA Approval)
  • sabizabulin(Pending FDA approval)
  • fexapotide(Phase 3 Clinical trial)
  • diatrizoic acid
  • drotaverine
  • diethyl phthalate
  • enclomiphene
  • epalrestat
  • ethamsylate
  • flupirtine
  • imidurea
  • sodium glycolate
  • feracrylum
  • ethacridine
  • furazolidone/metronidazole
  • ozagrel hydrochloride
  • leptazol
  • l-glutamic acid /vitamin B complex
  • etizolam
  • etizolam/propranolol
  • ethoheptazine citrate
  • etophylline and theophylline
  • etophylline
  • finger millet
  • drotaverine/mefenamic acid
  • dichloroxylenol
  • pneumococcal 7-valent vaccine
  • diclofenac and metaxalone
  • dipivefrin ophthalmic
  • enbucrilate
  • potassium citrate and citric acid
  • potassium gluconate
  • aclarubicin
  • alfuzosin/dutasteride
  • adrenochrome monosemicarbazone
  • selenium sulfide topical
  • sertaconazole
  • amorolfine cream
  • amsacrine
  • amylmetacresol
  • sulfonated phenolics in aqueous solution
  • technetium Tc-99m sulfur colloid
  • raltitrexed
  • romiplostim
  • acediasulfone
  • azulene
  • acebrophylline
  • clonazepam/escitalopram oxalate
  • allylestrenol
  • andrographolide
  • artemotil
  • technetium Tc-99m sestamibi
  • rubidium Rb-82
  • somapacitan
  • sodium sulfate, magnesium sulfate and potassium sulfate
  • almitrine
  • gramicidin
  • nikethamide
  • technetium Tc-99m sodium pertechnetate
  • betiatide
  • prilocaine/epinephrine
  • amlexanox
  • acetaminophen/salicylamide/phenyltoloxamine
  • neomycin topical
  • zilucoplan
  • antazoline and xylometazoline
  • toripalimab
  • iron isomaltoside
  • meningococcal A C Y and W polysaccharide tetanus toxoid conjugate vaccine
  • meningococcal A C Y and W-135 diphtheria conjugate vaccine
  • tetradecyl Sulfuric Acid
  • benzoyl peroxide, clindamycin phosphate, adapalene
  • ethylephedrine
  • actarit
  • pyrantel tartrate
  • tenofovir disoproxil fumarate or tenofovir DF
  • melitracen
  • amitriptylinoxide(Phase 4 Clinical Trials)
  • threonine
  • ditiocarb zinc
  • epicriptine
  • levallorphan
  • kinetin
  • laurocapram
  • pentagastrin
  • parthenolide
  • nicoboxil
  • protionamide
  • prulifloxacin
  • proscillaridin
  • tizanidine and rofecoxib
  • tolnaftate, gentamicin, chinoform and betamethasone valerate
  • pine bark extract
  • pipenzolate methylbromide
  • bephenium hydroxynaphthoate
  • niclosamide
  • pyrvinium
  • pipenzolate methylbromide/phenobarbitone
  • piracetam/ginkgo biloba/vinpocetine
  • benzyl benzoate/disulfiram
  • benzyl benzoate
  • loperamide/simethicone
  • piroctone olamine
  • sodium fusidate
  • piroxicam topical/capsaicin/menthol/methyl salicylate
  • sodium metabisulfite
  • sodium lauryl sulfate
  • taspoglutide
  • glyclopyramide
  • tolnaftate, gentamicin, iodochlorohydroxyquinoline, chlorocresol, betamethasone valerate
  • serratiopeptidase
  • sodium antimony gluconate
  • triamterene / benzthiazide
  • tribenoside / lidocaine
  • triclocarban
  • triprolidine/dextromethorphan  
  • vitamins/minerals/omega-3 Fatty acids
  • soyabean oil
  • sucralfate/oxethazaine
  • sucralfate/tinidazole/povidone iodine
  • sodium cromoglycate
  • aloe vera/liquid paraffin/white soft paraffin
  • aloe vera/jojoba oil/vitamin E
  • allantoin/triclosan/vitamin e/zinc oxide
  • alpha-Lipoic acid/minerals/multivitamins
  • alprazolam/paracetamol
  • alprazolam/melatonin
  • azithromycin/ambroxol
  • atorvastatin/clopidogrel/aspirin
  • aceclofenac, paracetamol and serratiopeptidase
  • alfacalcidol, vitamin B-complex, minerals and antioxidants
  • alpha- lipoic acid, vitamin b complex and vitamin c
  • alpha-galactosidase and simethicone
  • alpha-galactosidase, amylase, proteases, lipase and lactase
  • amikacin and cefepime
  • aminophylline, ephedrine and phenobarbitone
  • artesunate, sulphadoxine and pyrimethamine
  • finasteride/tamsulosin
  • flavoxate/ofloxacin
  • fenofibrate/metformin
  • lignocaine, hydrocortisone topical and allantoin
  • linoleic acid and sodium lactate
  • troxerutin
  • meclizine/nicotinic acid
  • mecobalamin/ginkgo Biloba
  • spirulina
  • loperamide and furazolidone
  • ketoconazole/cetrimide
  • ketoconazole/zinc pyrithione
  • lercanidipine/atenolol
  • levocetirizine/montelukast/ambroxol
  • levarterenol
  • levocetirizine/phenylpropanolamine 
  • indapamide/amlodipine
  • itopride/methyl polysiloxane
  • mebendazole/levamisole
  • eberconazole/mometasone
  • gliclazide/metformin/pioglitazone
  • fluconazole/tinidazole
  • haemocoagulase
  • halometasone
  • hesperidin
  • imipramine/chlordiazepoxide
  • idebenone / l-arginine / zinc sulphate/selenium/proanthocyanidin
  • mecobalamin and piracetam
  • mesterolone
  • mosapride and pantoprazole
  • atorvastatin, co enzyme q10, vitamin e, zinc, and selenium
  • azithromycin and benzalkonium chloride
  • beta carotene, vitamin c, vitamin e, minerals, lutein, eicosapentaenoic acid, docosahexenoic acid and vit b12
  • alpha-galactosidase
  • aloe vera gel/vitamin e/lactic acid
  • aloe vera gel/jojoba/vitamin e/glycerine
  • famotidine and domperidone
  • faropenem medoxomil
  • nedosiran
  • fluconazole/ornidazole/azithromycin
  • ebastine/montelukast
  • eberconazole
  • dienogest/estradiol valerate
  • ambroxol/salbutamol
  • benzoic acid/salicylic acid/ichthammol/ triamcinolone acetonide
  • desloratadine/ambroxol
  • dexibuprofen/paracetamol
  • atorvastatin/ramipril
  • diastase
  • diastase and simethicone
  • diazepam and propranolol
  • dexrabeprazole / domperidone
  • dexrabeprazole
  • dexketoprofen /paracetamol
  • beta carotene/vitamin C/minerals
  • aloe vera gel/urea
  • aloe vera gel/glycerine
  • alpha-lipoic acid/benfotiamine/chromium/folic acid/mecobalamin / vit b6
  • alprazolam/propranolol
  • alprazolam /sertraline
  • ibuprofen/dextropropoxyphene
  • ambroxol/cetirizine/phenylephrine/ guaiphenesin/menthol
  • dextropropoxyphene/dexchlorpheniramine maleate/bromhexine
  • promegestone
  • batroxobin
  • bencyclane
  • benfluorex
  • acetylpheneturide
  • abarelix
  • abetimus
  • naftidrofuryl
  • nalorphine
  • oxiracetam
  • letosteine
  • lafutidine
  • leuprorelin
  • levodropropizine
  • glutaral
  • losartan/ramipril
  • gallopamil
  • lanatoside c
  • lauromacrogol
  • gestodene
  • aceclofenac/methyl salicylate/menthol/linseed oil/capsaicin
  • aceclofenac/paracetamol/tizanidine
  • alginic acid/magaldrate/simethicone
  • aceclofenac/paracetamol
  • aceclofenac/rabeprazole
  • alginic acid
  • pantoprazole and domperidone
  • urokinase
  • rimiterol
  • olanzapine/fluoxetine
  • normethadone/hydroxyephedrine
  • myrtol
  • moxonidine
  • propylhexedrine
  • sodium hypochlorite solution
  • sodium chloride/sodium citrate
  • Hepatitis B Vaccine (Recombinant [Adjuvanted])
  • Hepatitis B Vaccine (Recombinant)
  • aceclofenac and serratiopeptidase
  • levosulpiride
  • niaprazine
  • tromantadine
  • trimetazidine
  • vinburnine
  • mizoribine
  • molgramostim
  • mosapride
  • eugenol
  • tolperisone
  • etamsylate
  • etynodiol
  • mizolastine
  • metenolone
  • reproterol
  • rebamipide
  • mephenoxalone
  • metandienone
  • furosemide/spironolactone
  • hydroxycarbamide
  • tenonitrozole
  • fenoverine
  • fenquizone
  • tiapride
  • tibolone
  • furazolidone
  • furosemide & amiloride
  • fosfestrol
  • fluclorolone
  • flubendazole
  • tertatolol
  • tetracosactide
  • tetryzoline
  • tolciclate
  • trapidil
  • troxipide
  • temoporfin
  • telbivudine
  • teprenone
  • hexamidine
  • mebhydrolin
  • mepartricin
  • fencamfamin
  • medazepam
  • theodrenaline
  • thiamazole
  • thiocolchicoside
  • psilocybin
  • veralipride
  • pyritinol
  • opipramol
  • oprelvekin
  • betamethasone + gentamicin
  • betamethasone + neomycin
  • betamethasone + salicylic acid
  • oxedrine
  • bopindolol
  • orgotein (investigational)
  • oxaceprol
  • ormeloxifene
  • bevantolol
  • bifemelane
  • clebopride
  • demoxytocin
  • cicletanine
  • cefsulodin
  • chlortalidon
  • sisomicin
  • somatrem
  • carbazochrome
  • caroverine
  • cathine
  • ipriflavone
  • isepamicin
  • silymarin
  • simethicone
  • sermorelin
  • diloxanide
  • dimethindene
  • diosmin/hesperidin
  • calamine
  • canrenone
  • captodiame
  • imidapril
  • cefetamet
  • cefodizime
  • cefoperazone + sulbactam
  • ivermectin + albendazole
  • serrapeptase
  • bromisoval
  • beraprost
  • pridinol
  • proglumide
  • bamipine
  • barnidipine
  • bamifylline
  • benzbromarone
  • betamethasone/fusidic acid
  • para-chlorophenol
  • pantethine
  • nomifensine
  • pemoline
  • parnaparin
  • pentolinium
  • nialamide
  • novobiocin
  • nicergoline
  • octocrylene
  • octisalate
  • oftasceine
  • oxolamine
  • oxyphencyclimine
  • penfluridol
  • pentoxyverine
  • phenoxymethylpenicillin
  • picloxydine
  • pilsicainide hydrochloride
  • piperazine
  • pirarubicin
  • policresulen
  • prifinium bromide
  • prethcamide
  • pristinamycin
  • pirenzepine
  • piribedil
  • pimethixene
  • pargyline
  • phosphatidyl choline
  • phthalylsulfathiazole
  • phytomenadione
  • pranlukast
  • pinazepam
  • oxyphenonium
  • noxytiolin
  • periciazine
  • pethidine
  • phenindamine
  • histidine
  • isoleucine
  • proline
  • lauric acid
  • lymecycline
  • hypromellose
  • abiraterone acetate and niraparib
  • ichthammol
  • levamisole
  • naftazone
  • nefopam
  • oxprenolol
  • oxybuprocaine
  • elranatamab-bcmm
  • lapyrium
  • isoaminile
  • iotrolan
  • mazindol
  • masoprocol
  • lypressin
  • meradimate
  • molsidomine
  • monobenzone
  • mequinol/gluconolactone/ lactobionic acid/ arbutin
  • medifoxamine
  • mebutamate
  • metergoline
  • methantheline
  • methdilazine
  • metocurine
  • micronomicin
  • metaraminol
  • mephenesin
  • menadione
  • medrysone
  • metixene
  • levobetaxolol
  • guaiacol glycerol ether
  • eucalyptol
  • sodium tetradecyl sulfate
  • sugammadex
  • carbetocin
  • certoparin
  • chlorcyclizine/pseudoephedrine
  • cephapirin
  • indecainide
  • iobitridol
  • iomeprol
  • chlorphenesin
  • msud analog
  • msud maxamum
  • iceland moss
  • glutethimide
  • hexachlorophene
  • haloprogin
  • deferoxamine
  • ethchlorvynol
  • dexpanthenol topical
  • etilefrine
  • deslanoside
  • carbocromen
  • diazolidinylurea
  • dibenzepin
  • etofamide
  • guanoxan
  • halazepam
  • guanadrel sulfate
  • dapiprazole
  • soapwort
  • debrisoquine
  • l-tryptophan
  • chlormerodrin
  • chlorquinaldol
  • cetrimonium
  • carbocisteine
  • chlorcyclizine/codeine
  • technetium Tc-99m tetrofosmin
  • technetium Tc-99m disofenin
  • technetium Tc-99m gluceptate
  • technetium Tc-99m labeled red blood cells
  • amylmetacresol/dextromethorphan hydrobromide
  • anileridine phosphate
  • pyrethrins
  • pyrantel pamoate
  • quinagolide
  • spiramycin
  • standard hyperkalemic cardioplegia solution
  • technetium tc-99m mertiatide
  • technetium tc-99m medronate
  • bemotrizinol / bisoctrizole
  • benfotiamine
  • bemotrizinol + titanium dioxide + zinc oxide
  • technetium Tc-99m oxidronate
  • technetium Tc-99m pentetate
  • technetium Tc-99m pyrophosphate
  • benziodarone
  • octinoxate/bisoctrizole
  • bicisate dihydrochloride
  • technetium Tc-99m bicisate
  • norelgestromin/ethinyl estradiol
  • norgestimate/ethinyl estradiol
  • ximelagatran (investigational)
  • xamoterol
  • trioxsalen
  • poly-urea urethane
  • rilmenidine
  • pemirolast
  • oxitriptan
  • beclomethasone, intranasal
  • thimerosal
  • camphor gel
  • camphor
  • mumps virus vaccine, live
  • rubella virus vaccine, live
  • aluminum chloride (dental)
  • alum irrigation
  • framycetin, phenylephrine, and gramicidin
  • ombitasvir, paritaprevir, ritonavir, and dasabuvir
  • olipudase alfa
  • etonogestrel/ethinyl estradiol
  • mycophenolate
  • fluoroestradiol F 18
  • donor organ cardioplegia solution
  • fluciclovine F 18
  • fusidic acid (ophthalmic)
  • fusidic acid and hydrocortisone
  • framycetin, dexamethasone, and gramicidin
  • fludeoxyglucose F-18
  • fluorouracil/salicylic acid
  • indium In-111 oxyquinoline
  • indium In-111 pentetreotide
  • indium In-111 capromab pendetide
  • lusutrombopag
  • mitomycin (ophthalmic)
  • mifepristone and misoprostol
  • minoxidil (systemic)
  • methyl aminolevulinate (topical)
  • methyl folate, methylcobalamin, and acetylcysteine
  • ciclesonide/formoterol/tiotropium
  • nedocromil (Oral Inhalation)
  • batefenterol (Investigational)
  • neostigmine and glycopyrrolate
  • nepafenac ophthalmic
  • netupitant/palonosetron
  • meperidine and promethazine
  • mepivacaine and levonordefrin
  • maltodextrin
  • medical cannabis
  • medium chain triglycerides
  • mometasone/glycopyrrolate (glycopyrronium)/ indacaterol
  • moxifloxacin ophthalmic
  • neomycin/fluocinolone
  • nadroparin
  • iodine I-125 iothalamate
  • amikacin liposome (oral inhalation)
  • bupivacaine liposome
  • natamycin
  • lopinavir and ritonavir
  • lysine
  • macitentan and tadalafil
  • mitomycin pyelocalyceal
  • moclobemide
  • mometasone and indacaterol
  • efinaconazole
  • blue-green algae
  • indocyanine green
  • follitropin beta
  • lumasiran
  • glycerin/lidocaine
  • edrophonium/atropine
  • indigo carmine
  • lutropin alfa
  • instant glucose/intravenous dextrose
  • iobenguane I-123
  • ixekizumab
  • isosulfan blue dye
  • levofloxacin ophthalmic
  • levonorgestrel oral/ferrous bisglycinate/ ethinylestradiol
  • ethinyl estradiol/levonorgestrel transdermal
  • hydroquinone
  • hydroxypropyl methylcellulose
  • icodextrin
  • lipid emulsion (soybean, medium-chain triglyceride, olive, and fish oils; [SMOF])
  • iodinated I 125 albumin
  • iodinated I 131 albumin
  • lipid emulsion (plant oil-based)
  • levonorgestrel intrauterine
  • levonorgestrel/ethinyl estradiol
  • lactic acid and sodium-PCA
  • lactated Ringer solution
  • ketotifen (systemic)
  • lanolin
  • leuprolide and norethindrone
  • levodopa and benserazide
  • gonadorelin acetate
  • hemodialysis solutions
  • nirsevimab
  • gentian violet
  • gallium ga-68 dotatate
  • fusidic acid and betamethasone
  • gallium citrate Ga-67
  • gadopentetate dimeglumine
  • gadofosveset
  • follitropin delta
  • follitropin alfa and lutropin alfa
  • follitropin alfa
  • rocatinlimab
  • grass pollens allergen extract
  • flotufolastat F18
  • fluorescein ophthalmic
  • barium
  • balanced salt solution
  • air polymer type A intrauterine device
  • clodronate
  • bentoquatam
  • clobetasone
  • alfacalcidol
  • citric acid/glucono-delta-lactone/magnesium carbonate
  • benzoin
  • desirudin
  • immune globulin IV (IGIV)
  • dequalinium
  • pseudoephedrine/desloratadine
  • clofedanol
  • cyproterone and ethinyl estradiol
  • dextranomer and hyaluronic acid or derivatives
  • diatrizoate meglumine and diatrizoate sodium
  • glucosamine sulfate, chondroitin sulfate and Msm
  • squill
  • gotu kola
  • blessed thistle
  • bitter melon
  • apraclonidine
  • chlophedianol/dexbrompheniramine/pseudoephedrine
  • wild jujube
  • chitosan
  • cilazapril/hydrochlorothiazide
  • dexbrompheniramine and phenylephrine
  • diethylene triamine penta-acetic acid
  • dexchlorpheniramine and pseudoephedrine
  • lily of the valley
  • diflucortolone
  • corydalis
  • lemon balm
  • MSM
  • calcium polystyrene sulfonate
  • caprylidene
  • peppermint oil
  • efavirenz/lamivudine/tenofovir DF
  • emtricitabine/tenofovir DF /efavirenz
  • dutasteride/tamsulosin
  • milk thistle
  • centaury
  • horseweed
  • lycopus
  • agrimony
  • alfalfa
  • kava
  • cetrorelix
  • cetylpyridinium
  • chlophedianol and dexbrompheniramine
  • betahistine
  • choline C-11
  • boric acid vaginal suppository
  • aluminum acetate
  • aluminum chloride hexahydrate
  • 14-C urea breath test
  • absorbable collagen
  • valoctocogene roxaparvovec-rvox
  • amlodipine and celecoxib
  • aspirin and omeprazole
  • azilsartan and chlorthalidone
  • landiolol (Pending FDA approval)
  • isosorbide dinitrate/hydralazine
  • losartan/hydrochorothiazide
  • udenafil
  • dextromethorphan/quinidine
  • onasemnogene abeparvovec
  • orphenadrine/aspirin/caffeine
  • trace elements
  • sodium phenylbutyrate/ taurursodiol
  • fish oil triglycerides
  • infant formula
  • glutamine
  • chloroquine phosphate
  • afatinib
  • quinidine gluconate
  • methylergonovine
  • prothrombin complex concentrate, human
  • BCG intravesical live
  • capivasertib
  • cedazuridine
  • carbonyl iron
  • iron dextran complex
  • lovotibeglogene autotemcel (FDA Approval Pending)
  • sodium benzoate/sodium phenylacetate
  • mineral oil otic
  • zolmitriptan transdermal
  • midazolam intranasal
  • fosinopril/hydrochlorothiazide
  • caplacizumab
  • arginine
  • sodium phenylbutyrate
  • meloxicam/rizatriptan
  • manganese
  • acetaminophen/pamabrom/pyridoxine
  • varicella zoster immune globulin, human
  • amitriptyline/perphenazine
  • narsoplimab (Pending FDA Approval)
  • amlodipine/perindopril
  • imiglucerase
  • canagliflozin/metformin
  • tafamidis meglumine
  • somatrogon-ghla
  • glimepiride/rosiglitazone
  • becaplermin
  • lithium
  • loxapine inhaled
  • nicotine transdermal
  • tixagevimab and cilgavimab (Investigational)
  • muromonab CD3
  • ansuvimab
  • coal tar bath products
  • fibrin sealant
  • arimoclomol (FDA Approval Pending)
  • varenicline intranasal
  • aducanumab
  • oxycodone/naloxone
  • ritlecitinib
  • sodium polystyrene sulfonate
  • calcipotriene/betamethasone
  • calcium hydroxylapatite
  • cantharidin topical
  • doxepin cream
  • clocortolone
  • formaldehyde topical
  • sodium sulfide topical
  • collagenase
  • selegiline transdermal
  • foscarbidopa/foslevodopa (FDA approval pending)
  • saxagliptin/metformin
  • linagliptin/metformin
  • linzagolix (FDA approval pending)
  • efgartigimod/hyaluronidase SC
  • elamipretide (Pending FDA approval)
  • rozanolixizumab
  • diazoxide
  • glimepiride/pioglitazone
  • cipaglucosidase alfa
  • dihydroergotamine intranasal
  • delandistrogene moxeparvovec
  • beremagene geperpavec
  • hyaluronic acid and derivatives
  • hyaluronic acid, non-animal stabilized
  • eplontersen (FDA Approval Pending)
  • nitric oxide gas
  • sodium phenylbutyrate and taurursodiol
  • treprostinil SC
  • viltolarsen
  • albuterol/ipratropium
  • budesonide inhaled
  • budesonide rectal
  • palovarotene
  • sodium sulfate/potassium chloride/magnesium sulfate/polyethylene glycol
  • amino acids mixture
  • aminobenzoate potassium
  • elivaldogene autotemcel
  • naproxen and sumatriptan
  • sumatriptan intranasal
  • alglucerase
  • metformin/rosiglitazone
  • ertugliflozin/metformin
  • elosulfase alfa
  • calcium carbonate/magnesium hydroxide
  • starch suppository
  • abicipar pegol (FDA Approval Pending)
  • riboflavin 5′-phosphate ophthalmic
  • povidone ophthalmic
  • glycerin oropharyngeal
  • dimethicone topical
  • menthol topical, dimethicone topical
  • pramoxine topical, menthol topical and dimethicone topical
  • phosphorated carbohydrate
  • brilliant blue G ophthalmic
  • brolucizumab intravitreal
  • purified water, ophthalmic
  • hydroxyethyl cellulose ophthalmic
  • ranibizumab intravitreal implant
  • sodium chloride hypertonic, ophthalmic 
  • cetirizine ophthalmic
  • phentolamine ophthalmic
  • ganciclovir ophthalmic
  • triamcinolone intravitreal
  • ocriplasmin intravitreal
  • atoltivimab/maftivimab/odesivimab
  • pegcetacoplan intravitreal
  • triamcinolone acetonide extended-release injectable suspension
  • tobramycin/loteprednol ophthalmic
  • 2-octyl cyanoacrylate
  • vitamins A & D topical
  • diphenhydramine/allantoin topical
  • pyrethrins/piperonyl butoxide
  • lodoxamide ophthalmic
  • obeticholic acid
  • fluocinolone intravitreal implant
  • sincalide
  • linaclotide
  • nedocromil ophthalmic
  • cysteamine ophthalmic
  • avacincaptad pegol intravitreal
  • azelastine ophthalmic
  • bacitracin ophthalmic
  • propylene glycol ophthalmic
  • rimexolone ophthalmic
  • metoclopramide intranasal
  • mirikizumab
  • netarsudil ophthalmic
  • cenegermin
  • dexamethasone ophthalmic insert
  • prednisolone ophthalmic
  • phenylephrine and cocoa butter rectal
  • phenylephrine and witch hazel topical
  • phenylephrine, pramoxine, glycerin and petrolatum rectal
  • bisacodyl rectal
  • aluminum hydroxide/magnesium carbonate
  • aluminum hydroxide/magnesium hydroxide
  • hyoscyamine spray
  • methenamine/methylene blue/ hyoscyamine/ sodium phosphate monobasic/ phenyl salicylate
  • phenylephrine
  • chlorophyll
  • castor oil
  • cholic acid
  • phenol oropharyngeal
  • articaine/epinephrine
  • antithymocyte globulin equine
  • aluminum hydroxide/magnesium trisilicate
  • methenamine/hyoscyamine
  • hydrocortisone topical/pramoxine topical 
  • sodium fluoride topical
  • mesna
  • C1 esterase inhibitor recombinant
  • menthol and pectin
  • menthol oropharyngeal
  • pectin oropharyngeal
  • gepirone
  • Goldenseal
  • polyethylene glycol and electrolytes
  • polyethylene glycol/electrolytes/sodium ascorbate/ascorbic acid
  • brompheniramine/pseudoephedrine/dextromethorphan
  • brompheniramine phenylephrine
  • acetaminophen/doxylamine/phenylephrine
  • doxylamine/acetaminophen/pseudoephedrine/dextromethorphan
  • acetaminophen/doxylamine/dextromethorphan
  • acetaminophen/doxylamine/dextromethorphan/phenylephrine
  • eslicarbazepine
  • fluticasone and salmeterol
  • codeine, acetaminophen, butalbital and caffeine
  • codeine, chlorpheniramine and phenylephrine
  • iodine
  • povidone iodine
  • butalbital/aspirin/caffeine/codeine
  • polyethylene glycol 400/propylene glycol ophthalmic 
  • pegvaliase
  • amivantamab
  • iopamidol
  • codeine and pseudoephedrine
  • emtricitabine, rilpivirine, tenofovir DF
  • penicillin G aqueous
  • miconazole topical
  • miconazole vaginal
  • ciprofloxacin inhaled (Pending FDA approval)
  • ceftazidime/avibactam
  • ceftolozane/​tazobactam
  • aztreonam inhalation
  • amphotericin B cholesteryl sulfate
  • miconazole oral
  • elvitegravir/cobicistat/emtricitabine/tenofovir DF
  • isavuconazonium sulfate
  • dapivirine intravaginal (FDA Approval Pending)
  • lamivudine/raltegravir
  • codeine/triprolidine/pseudoephedrine
  • cadexomer iodine
  • brompheniramine/pseudoephedrine
  • codeine/acetaminophen
  • codeine/guaifenesin
  • beclomethasone inhaled
  • epoetin beta/methoxy polyethylene glycol
  • voreloxin(Orphan Drug)
  • rociletinib
  • pitcher plant
  • phosphatidylserine
  • telotristat ethyl
  • copper CU 64 dotatate
  • urea topical
  • exenatide subdermal implant
  • asenapine transdermal
  • ethiodized oil
  • urea oral
  • miglustat
  • acalisib(Investigational)
  • acetophenazine
  • guggul
  • aceneuramic acid
  • mestranol/norethindrone
  • reishi
  • lactitol
  • vonoprazan fumarate
  • motherwort
  • silver nitrate
  • salicylic acid/sulfur shampoo
  • salicylic acid topical
  • ketorolac ophthalmic
  • ketoconazole topical
  • Japanese encephalitis virus vaccine
  • dibucaine topical ointment
  • ketorolac intranasal
  • ketorolac/phenylephrine ophthalmic
  • rotavirus oral vaccine, live
  • guarana
  • hops
  • krill oil
  • salicylic acid/coal tar shampoo
  • sufentanil SL
  • pancrelipase
  • passion flower
  • pepdite one plus
  • nivolumab and relatlimab
  • relatlimab (Pending FDA Approval)
  • benzalkonium chloride/benzocaine
  • ketotifen, drug-eluting contact lens
  • calcitriol topical
  • oxymetazoline topical
  • alclometasone topical
  • capsaicin topical
  • diclofenac/misoprostol
  • diclofenac ophthalmic
  • diclofenac topical
  • pramoxine/calamine topical
  • veverimer
  • tolazoline
  • olopatadine ophthalmic
  • lutetium lu 177-dota-tate
  • lutetium lu 177 vipivotide tetraxetan
  • strontium 89 chloride
  • interferon alfa n3
  • lutetium Lu 177- Diethylenetriamine Pentaacetic acid-omburtamab (FDA Approval Pending)
  • samarium sm 153 lexidronam
  • cytomegalovirus immune globulin (CMV IG)
  • antithymocyte globulin rabbit
  • inolimomab (Pending FDA Approval)
  • olopatadine intranasal
  • olopatadine intranasal/​mometasone, intranasal
  • benzocaine/butamben/tetracaine topical
  • antipyrine/benzocaine/phenylephrine
  • dyclonine/menthol
  • surufatinib
  • fruquintinib
  • dostarlimab
  • hepatitis B immune globulin (HBIG)
  • remestemcel-L
  • benzocaine/menthol oropharyngeal
  • interferon beta 1b
  • tetracaine/oxymetazoline intranasal
  • benzocaine oropharyngeal
  • benzalkonium chloride/menthol/petrolatum topical
  • inamrinone
  • alpha 1 proteinase inhibitor
  • potassium bicarbonate/potassium citrate
  • potassium phosphate/sodium acid phosphate
  • asparaginase Erwinia chrysanthemi recombinant
  • motixafortide
  • pegloticase
  • etesevimab
  • Rho(D) immune globulin
  • tetanus immune globulin (TIG)
  • reltecimod (pending FDA approval)
  • avasopasem
  • trimethoprim/polymyxin B ophthalmic
  • naphazoline ophthalmic
  • sulfacetamide topical
  • sirolimus intravitreal (pending FDA approval)
  • sirolimus protein bound
  • sirolimus topical
  • glycopyrronium tosylate topical
  • sofpironium
  • olmesartan, amlodipine and hydrochlorothiazide
  • dovitinib (Pending FDA Approval)
  • epinephrine inhaled
  • quizartinib (Pending FDA Approval)
  • ranibizumab intravitreal injection
  • sodium hyaluronate
  • bacitracin and lidocaine topical
  • brimonidine topical
  • benzoyl peroxide and tretinoin topical
  • talquetamab
  • betrixaban
  • acetaminophen/caffeine/pyrilamine
  • fentanyl transmucosal
  • bacitracin topical
  • buprenorphine,long-acting injection
  • buprenorphine buccal
  • nalmefene intranasal
  • sulbactam/durlobactam
  • metronidazole topical 
  • daratumumab/hyaluronidase
  • glofitamab
  • rituximab-hyaluronidase
  • drospirenone/ethinyl estradiol/levomefolate
  • loncastuximab tesirine
  • ingenol mebutate topical
  • momelotinib
  • trastuzumab/deruxtecan
  • trastuzumab/hyaluronidase
  • trastuzumab duocarmazine
  • lifileucel
  • umbralisib
  • eflornithine/sulindac
  • cytarabine/daunorubicin liposomal
  • doxorubicin liposomal
  • epcoritamab
  • lanadelumab  
  • esomeprazole/naproxen 
  • terbinafine topical
  • ravulizumab
  • clotrimazole topical
  • choline magnesium trisalicylate
  • tacrolimus ointment
  • mechlorethamine topical
  • donislecel
  • pozelimab (Pending FDA Approval)
  • human rabies immune globulin (HRIG)
  • melphalan flufenamide
  • sintilimab (Pending FDA Approval)
  • oportuzumab monatox (Pending FDA Approval)
  • sotorasib
  • irinotecan liposomal
  • sulfur topical
  • silver sulfadiazine
  • capsaicin transdermal
  • sutimlimab
  • tretinoin topical
  • acetaminophen rectal
  • menthol topical
  • naftifine
  • oatmeal, colloidal topical
  • oxiconazole
  • methylsalicylate/menthol topical
  • C1 inhibitor human
  • lifitegrast ophthalmic
  • prednisolone/sulfacetamide ophthalmic
  • mannitol inhalation
  • ofloxacin otic
  • petrolatum & mineral oil topical
  • clascoterone topical
  • gefapixant (Pending FDA Approval)
  • colesevelam
  • technetium Tc 99m succimer
  • nebivolol/valsartan
  • ciprofloxacin/fluocinolone acetonide, otic
  • finafloxacin otic
  • magnesium hydroxide/mineral oil
  • phenylephrine/mineral oil/petrolatum rectal
  • carbamide peroxide oral
  • atropine ophthalmic
  • sodium sulfacetamide/sulfur
  • sulfacetamide ophthalmic
  • lucinactant
  • benzonatate
  • besifloxacin ophthalmic
  • benzhydrocodone/acetaminophen
  • beractant
  • trimagnesium citrate anhydrous
  • vitamin b2
  • carbamide peroxide otic
  • mineral oil topical
  • ethyl alcohol intranasal
  • boric acid/alcohol otic
  • absorbable gelatin compressed sponge, USP
  • absorbable gelatin sponge, USP
  • vincristine liposomal
  • technetium Tc 99m albumin aggregated injection
  • metaproterenol
  • budesonide inhaled/formoterol/glycopyrrolate inhaled
  • epinephrine racemic
  • umeclidinium bromide/vilanterol inhaled
  • indacaterol, inhaled/glycopyrrolate inhaled
  • betaine  
  • laronidase 
  • estrogens esterified/methyltestosterone            
  • cerliponase alfa
  • ertugliflozin/sitagliptin
  • hawthorn
  • shepherd’s purse
  • thiamine
  • naphazoline/glycerin ophthalmic
  • oxymetazoline ophthalmic
  • dorzolamide
  • dexamethasone intraocular
  • dexamethasone/ciprofloxacin
  • dexamethasone ophthalmic
  • metipranolol ophthalmic
  • timolol ophthalmic
  • boron
  • fezolinetant
  • pegunigalsidase alfa-iwxj
  • biotin
  • pantothenic acid
  • silicon
  • sodium acid phosphate
  • hypochlorous acid topical
  • methenamine/sodium acid phosphate
  • aviptadil 
  • bremelanotide
  • glucagon intranasal
  • metformin and repaglinide
  • bai ji
  • pau d’arco
  • juzentaihoto
  • mistletoe
  • quercetin
  • rosemary
  • sheng di huang
  • chasteberry
  • maitake
  • grapefruit
  • lentinan
  • juniper
  • nettle
  • parsley
  • rose hips
  • tongkat ali
  • horny goat weed
  • damiana
  • yohimbe
  • insulin NPH
  • aprocitentan
  • noni Juice
  • sodium iodide I-131
  • green tea
  • sea cucumber
  • wheat germ extract
  • fenofibrate micronized 
  • rogisen
  • danshen
  • lutein
  • witch hazel
  • dextroamphetamine transdermal
  • amphetamine/dextroamphetamine
  • hoodia
  • kolanut
  • boswellia
  • opuntia ficus indica
  • lavender
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  • tea tree oil
  • metformin/sitagliptin 
  • dapagliflozin/ metformin/saxagliptin  
  • antihemophilic factor recombinant
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  • volanesorsen  
  • omega 3 carboxylic acids
  • pericyazine
  • levomepromazine (methotrimeprazine)
  • betaxolol ophthalmic
  • respiratory syncytial virus vaccine, adjuvanted
  • phenylephrine hydrochloride and tropicamide ophthalmic
  • alirocumab
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  • factor IX
  • gentamicin topical
  • ansofaxine (Pending FDA Approval)
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  • factor IX, recombinant
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  • factor XIII A-subunit, recombinant
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  • fibrinogen, human
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  • metyrosine
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  • ipecac syrup
  • botulinum antitoxin, heptavalent
  • pentetate calcium trisodium
  • crotalidae polyvalent immune FAB (ovine)
  • dehydrated alcohol injection 
  • gold sodium thiomalate (Discontinued)
  • lactic acid/citric acid/potassium bitartrate vaginal
  • von Willebrand factor, recombinant
  • luspatercept
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  • crotalidae immune FAB (equine)
  • magnesium (Antidote)
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  • dextrose
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  • estradiol vaginal
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  • botulism immune globulin iv
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  • synthetic human angiotensin II
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  • tetrahydrozoline/zinc sulfate/hypromellose ophthalmic
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  • pemetrexate
  • methicillin
  • plasminogen 
  • acai
  • american ginseng
  • cordyceps
  • tramadol/acetaminophen
  • belladonna alkaloids/phenobarbital
  • erythromycin topical/benzoyl peroxide
  • glucosamine sulfate
  • panax ginseng (suppl/herb)
  • tolnaftate
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  • sulfur hexafluoride
  • sotrovimab
  • arbaclofen
  • rifampin/isoniazid
  • clindamycin /tretinoin topical
  • benzoyl peroxide/clindamycin topical
  • apremilast
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  • bamlanivimab and etesevimab
  • vilobelimab
  • gadobenate
  • pentosan polysulfate sodium
  • methylsalicylate/menthol/camphor topical
  • antivenin, black widow spider
  • benzoyl peroxide and hydrocortisone
  • clindamycin topical
  • isometheptene, dichloralphenazone and acetaminophen
  • acetaminophen and phenyltoloxamine
  • erythromycin topical
  • erythromycin ophthalmic
  • alpha hydroxy acids, topical
  • buprenorphine transdermal
  • butalbital/acetaminophen/caffeine
  • buprenorphine/samidorphan
  • buprenorphine subdermal implant
  • celecoxib/tramadol
  • drospirenone/ethinyl estradiol
  • resorcinol/sulfur
  • eflornithine
  • rifampin/isoniazid/pyrazinamide
  • tofersen
  • devil’s claw
  • ticarcillin/clavulanate
  • atropine/pralidoxime
  • aprepitant
  • suramin
  • phenelzine 
  • artichoke
  • american dogwood
  • attapulgite
  • atlantic cedar
  • axalimogene filolisbac
  • sodium thiosulfate & sodium nitrite
  • ataluren
  • omidubicel-onlv
  • capsicum
  • ginger
  • cryoprecipitate
  • bictegravir/emtricitabine/tenofovir DF
  • emtricitabine/tenofovir DF
  • fo-ti
  • siberian ginseng
  • granulocytes
  • zinc substituted heme C
  • zinc trihydroxide
  • ashwagandha 
  • cat’s claw
  • glandular products
  • SAMe
  • shark cartilage
  • altovis
  • feverfew
  • horse chestnut
  • magnesium aspartate
  • octacosanol
  • pleurisy root
  • star anise
  • butterbur
  • elderberry
  • licorice (Suppl/herb)
  • aconite
  • pentetate zinc trisodium
  • menthol topical/zinc oxide topical
  • corn-starch/kaolin/zinc oxide topical
  • 5-hydroxytryptophan (5-htp)
  • butcher’s broom
  • articulin
  • bearberry
  • goldenrod
  • progesterone, natural
  • black cohosh
  • wild yam
  • cranberry
  • dong quai
  • phytoestrogens
  • norethindrone
  • false Unicorn Root
  • raspberry Leaf
  • asafoetida
  • turmeric
  • dehydroepiandrosterone (DHEA)
  • hyaluronan
  • aliskiren/amlodipine
  • octreotide (Antidote)
  • tranexamic acid injection
  • duocal
  • neocate infant formula
  • pediatric Eo28
  • aloe
  • red clover
  • propolis
  • androstenedione
  • heartsease
  • comfrey
  • bilberry
  • chamomile
  • eyebright
  • calendula
  • sage
  • yucca
  • polypody
  • odevixibat
  • vinpocetine
  • olanzapine/samidorphan
  • creatine
  • yerba mate
  • spesolimab
  • azficel-T
  • tiludronate
  • estetrol and drospirenone
  • pseudoephedrine/fexofenadine
  • lincomycin
  • neomycin oral
  • fluocinolone acetonide, otic
  • tretinoin/ hydroquinone/ fluocinolone
  • halobetasol topical
  • hydrocortisone/​iodoquinol
  • penicillin G procaine /penicillin G benzathine
  • hydrocortisone probutate topical
  • colistin/neomycin/hydrocortisone/thonzonium otic
  • ebola zaire vaccine
  • hepatitis a/​b vaccine
  • vibegron
  • lindane
  • nystatin topical
  • respiratory syncytial virus (RSV) vaccine
  • chikungunya vaccine, live
  • tenecteplase
  • reteplase
  • anthrax vaccine adsorbed, adjuvanted
  • meningococcal ABCWY pentavalent vaccine
  • eculizumab
  • cholestyramine
  • tinzaparin
  • taurolidine/​citrate/​heparin
  • protein C concentrate
  • antithrombin alfa
  • antithrombin III
  • multivitamins, vision
  • ibuprofen/​chlorpheniramine/​pseudoephedrine
  • acetaminophen/ibuprofen
  • ibuprofen/pseudoephedrine
  • paclitaxel protein-bound
  • acetic acid vaginal
  • acetic acid otic
  • hydrocodone/ ibuprofen
  • methyl salicylate / isopropanol/ citronellyl acetate/ citric acid
  • ibuprofen and phenylephrine
  • acetylcysteine (Antidote)
  • iron/​folic acid/​vitamin/​mineral
  • iobenguane I-131
  • dolutegravir/rilpivirine
  • chlorhexidine topical
  • chlorhexidine oral
  • thyroid desiccated
  • proparacaine ophthalmic
  • podophyllum resin
  • phendimetrazine
  • phenoxybenzamine
  • polidocanol
  • phentermine and topiramate
  • piflufolastat F18
  • piperacillin/tazobactam
  • prednisolone and gentamicin ophthalmic
  • promethazine and codeine
  • poractant alfa
  • protamine sulfate
  • aflibercept intravitreal
  • prednicarbate
  • promethazine/dextromethorphan
  • codeine, phenylephrine, and promethazine
  • potassium phosphate
  • glatiramer acetate
  • gentamicin (Ophthalmic)
  • leniolisib
  • rezafungin
  • fluorometholone
  • dalfampridine
  • hydrocortisone topical 
  • empagliflozin and linagliptin
  • triamcinolone topical
  • minocycline topical
  • minocycline dental
  • ketotifen ophthalmic
  • darunavir and cobicistat
  • lidocaine topical
  • neomycin/polymyxin B/bacitracin/lidocaine (OTC)
  • lidocaine/ hydrocortisone
  • lidocaine anesthetic
  • lidocaine ophthalmic
  • lidocaine/tetracaine
  • desonide
  • dabigatran
  • fexofenadine
  • fluoride
  • decitabine and cedazuridine
  • dasiglucagon
  • hydroxypropyl cellulose ophthalmic
  • epoetin alfa
  • ibritumomab tiuxetan
  • trimethobenzamide
  • dexamethasone/ tobramycin
  • tafasitamab
  • valacyclovir
  • mebendazole
  • levoleucovorin
  • flaxseed
  • germanium
  • glutathione
  • lycopene
  • pygeum
  • horseradish
  • ziv-aflibercept
  • micafungin
  • trofinetide
  • taliglucerase alfa
  • tildrakizumab
  • sulopenem (Pending FDA Approval)
  • thyrotropin alfa
  • birch
  • thrombin, topical
  • tivozanib
  • tafluprost
  • methohexital
  • urea and hydrocortisone
  • unoprostone ophthalmic
  • trihexyphenidyl
  • ezetimibe
  • evolocumab
  • trifluridine and tipiracil
  • methenamine
  • misoprostol
  • miltefosine
  • rimantadine
  • maralixibat
  • coenzyme Q10
  • chlorella
  • garlic
  • forskolin
  • zavegepant
  • menotropins
  • margetuximab
  • meprobamate
  • melarsoprol
  • evening primrose oil
  • lemongrass
  • molindone
  • fenugreek
  • phytosterols
  • red yeast rice
  • uridine triacetate
  • tropicamide
  • incobotulinumtoxinA
  • Grape Seed Extract
  • carbachol ophthalmic
  • cosyntropin
  • cyclopentolate and phenylephrine
  • carteolol ophthalmic
  • pentazocine/naloxone
  • pentazocine/acetaminophen
  • casimersen
  • carisoprodol, aspirin, and codeine
  • carisoprodol
  • carboprost tromethamine
  • flurandrenolide
  • brinzolamide/brimonidine
  • betamethasone topical
  • omaveloxolone
  • bardoxolone
  • allogeneic processed thymus tissue
  • fluocinolone topical
  • tacrolimus topical
  • ruxolitinib topical
  • pimecrolimus topical
  • sofosbuvir, velpatasvir and voxilaprevir
  • sofosbuvir/velpatasvir
  • mitotane
  • elbasvir/​grazoprevir
  • wheat dextrin
  • vanadium
  • iron/folic acid/vitamin/mineral
  • molybdenum
  • sparsentan
  • velmanase alfa-tycv
  • pegcetacoplan
  • ferrous sulfate
  • cyclosporine ophthalmic
  • ferric pyrophosphate
  • ammonium lactate
  • etelcalcetide
  • iodoquinol
  • sucroferric oxyhydroxide
  • doxercalciferol
amlodipine/telmisartan + 

aliskiren 

may increase the hyperkalemic effect of angiotensin receptor II blockers

amifostine 

may increase the hypotensive effect of blood pressure-lowering agents

cilazapril

may increase the toxic effect of angiotensin receptor II blockers

enalapril

may increase the toxic effect of angiotensin receptor II blockers

enalaprilat

may increase the toxic effect of angiotensin receptor II blockers

lisinopril

may increase the toxic effect of angiotensin receptor II blockers

perindopril

may increase the toxic effect of angiotensin receptor II blockers

obinutuzumab 

may enhance the serum concentration of CYP3A4 inhibitors

sirolimus 

may decrease the therapeutic effect of drugs affecting gallbladder function

ubrogepant 

may enhance the serum concentration of CYP3A4 inhibitors

lonafarnib 

may enhance the serum concentration of CYP3A4 inhibitors

bromeperidol 

may increase the hypotensive effect of blood pressure lowering agents

fexinidazole 

may enhance the serum concentration of CYP3A4 substrates

indoramin

may increase the hypotensive effect of calcium channel blockers

bunazosin (Not available in the United States)

may increase the hypotensive effect of calcium channel blockers

terazosin

may increase the hypotensive effect of calcium channel blockers

labetalol 

may increase the hypotensive effect of calcium channel blockers

prazosin

may increase the hypotensive effect of calcium channel blockers

perphenazine

may increase the hypotensive effect of blood pressure-lowering agents

pimavanserin

may increase the hypotensive effect of blood pressure-lowering agents

chlorpromazine

may increase the hypotensive effect of blood pressure-lowering agents

pipotiazine

may increase the hypotensive effect of blood pressure-lowering agents

haloperidol

may increase the hypotensive effect of blood pressure-lowering agents

primidone

may increase the hypotensive effect of blood pressure-lowering agents

phenobarbital

may increase the hypotensive effect of blood pressure-lowering agents

amobarbital

may increase the hypotensive effect of blood pressure-lowering agents

butalbital

may increase the hypotensive effect of blood pressure-lowering agents

butabarbital

may increase the hypotensive effect of blood pressure-lowering agents

calcium acetate

may decrease the therapeutic effect of calcium channel blockers

calcium carbonate

may decrease the therapeutic effect of calcium channel blockers

calcium chloride

may decrease the therapeutic effect of calcium channel blockers

calcium citrate

may decrease the therapeutic effect of calcium channel blockers

calcium glucoheptonate

may decrease the therapeutic effect of calcium channel blockers

efonidipine

may increase the hypotensive effect of blood pressure-lowering agents

ropivacaine

may increase the hypotensive effect of blood pressure-lowering agents

halothane

may increase the hypotensive effect of blood pressure-lowering agents

fimasartan

may increase the hypotensive effect of blood pressure-lowering agents

indoramin

may increase the hypotensive effect of blood pressure-lowering agents

ethacrynic acid

may increase the hypotensive effect of calcium channel blockers

bumetanide

may increase the hypotensive effect of calcium channel blockers

muzolimine

may increase the hypotensive effect of calcium channel blockers

tanshinone I

may increase the toxic effect of angiotensin receptor II blockers

rosmarinic acid

may increase the toxic effect of angiotensin receptor II blockers

caryophyllene

may increase the toxic effect of angiotensin receptor II blockers

ursolic acid

may increase the toxic effect of angiotensin receptor II blockers

cepharanthine

may increase the toxic effect of angiotensin receptor II blockers

eplerenone

may increase the hyperkalemic effect of angiotensin receptor II blockers

spironolactone

may increase the hyperkalemic effect of angiotensin receptor II blockers

triamterene

may increase the hyperkalemic effect of angiotensin receptor II blockers

amiloride

may increase the hyperkalemic effect of angiotensin receptor II blockers

canrenoic acid

may increase the hyperkalemic effect of angiotensin receptor II blockers

iloperidone

may increase the hypotensive effect of calcium channel blockers

iloprost

may increase the hypotensive effect of calcium channel blockers

selexipag

may increase the hypotensive effect of calcium channel blockers

ajmaline 

may increase the toxic effect of sulfonamides

ouabain

may increase the toxic effect of thiazide and thiazide like diuretics

digitoxin

may increase the toxic effect of thiazide and thiazide like diuretics

digoxin

may increase the toxic effect of thiazide and thiazide like diuretics

citalopram

may increase the hyponatremic effect of thiazide and thiazide-like diuretics

escitalopram

may increase the hyponatremic effect of thiazide and thiazide-like diuretics

flibanserin

may increase the hyponatremic effect of thiazide and thiazide-like diuretics

fluoxetine

may increase the hyponatremic effect of thiazide and thiazide-like diuretics

mianserin

may increase the hyponatremic effect of thiazide and thiazide-like diuretics

paricalcitol

may increase the hypercalcemic effect of thiazide and thiazide like diuretics

Mechanism of action

amlodipine is a calcium channel blocker that works by blocking the entry of calcium into the cells of the blood vessels, thereby relaxing the blood vessels and allowing for better blood flow. This results in a decrease in blood pressure. amlodipine has a broad spectrum of activity and can effectively lower blood pressure in patients with mild to moderate hypertension
telmisartan, on the other hand, is an angiotensin receptor blocker (ARB) that works by blocking the action of angiotensin II, a hormone that causes blood vessels to narrow.

By blocking the action of angiotensin II, telmisartan helps to dilate blood vessels and lower blood pressure. It also effectively reduces the risk of cardiovascular events such as heart attack and stroke. When used together, amlodipine and telmisartan provide additive blood pressure-lowering effects, making them an effective combination therapy for the treatment of hypertension. The combination of these two medications has been shown to effectively lower blood pressure in many patients, including those with severe hypertension and those who have not achieved adequate blood pressure control with monotherapy

Spectrum

The combination of amlodipine and telmisartan has a broad spectrum of activity and is used to treat hypertension (high blood pressure) in many patients. The combination therapy is particularly effective in patients who have not achieved adequate blood pressure control with monotherapy or who have severe hypertension

Frequency defined:

10%

Peripheral edema (1-11%)

1-10%

Orthostatic hypotension (6%)

Back pain (2%)

Dizziness (3%)

Syncope (2%)

Post-marketing reports

asthenia, nausea, hypoglycemia, upper respiratory tract infection, jaundice, headache, coughing, fatigue, angioedema, gynecomastia, extrapyramidal syndrome

 

 

 

Contraindications

It is contraindicated in hypersensitivity and Patients with diabetes mellitus should not receive aliskiren in combination with them
Caution

  • Hypotension: It can lower blood pressure, leading to dizziness, light-headedness, and fainting. Patients should be cautious when standing up after sitting or lying down for an extended period.
  • Liver disease: It is metabolized in the liver, so it should be used cautiously in patients with liver disease.
  • Heart failure: It may worsen heart failure in some patients. It should be used cautiously in patients with heart failure or left ventricular dysfunction.
  • Pregnancy: It should not be used during pregnancy, as it can cause harm to the developing foetus. Women of childbearing age should use effective contraception while taking telmisartan

Pregnancy consideration:

It should not be used during pregnancy, as it can cause harm to the developing foetus

Lactation: Excretion of the drug in human breast milk is unknown

Pregnancy category:

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.

Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.

Category N: There is no data available for the drug under this category

Pharmacology

amlodipine is a dihydropyridine calcium channel blocker that blocks the influx of calcium ions into vascular smooth muscle cells, resulting in the relaxation of the blood vessels and a reduction in blood pressure. Amlodipine has a long duration of action and is typically given once daily telmisartan is an angiotensin II receptor blocker (ARB) that works by blocking the action of the hormone angiotensin II on its receptors in the blood vessels and other tissues. This results in the relaxation of the blood vessels and a reduction in blood pressure. Telmisartan has a long duration of action and is typically given once daily. In addition to its antihypertensive effects, telmisartan has been shown to have other beneficial effects, such as reducing inflammation and improving insulin sensitivity

Pharmacodynamics

amlodipine and telmisartan reduce blood pressure but do so through different mechanisms.amlodipine blocks calcium channels, while telmisartan works by blocking angiotensin II receptors

Pharmacokinetics

Absorption

telmisartan has a half-life of 24 hours, an onset of action of 1-2 hours, and a bioavailability of 42-58%, which is dose-dependent. amlodipine has a half-life of 30-50 hours, a bioavailability of 64-90%, and a Vd of 21 L/kg. Its peak plasma time is 6-12 hours

Distribution

Its volume of distribution (Vd) is 500 L, and its peak plasma time is 0.5-1 hour

Metabolism

telmisartan is highly protein-bound (>99.5%), and it is primarily metabolized in the liver to an inactive metabolite that is not metabolized by CYP enzymes. amlodipine is highly protein-bound (93-98%), and it is primarily metabolized in the liver by the P450 CYP3A4 enzyme

Elimination/excretion

telmisartan has a clearance of 800 mL/min, and it is mainly excreted in the faeces (97%). amlodipine has a clearance of 25 L/hr, and it is mainly excreted in the urine (70%)

Administration

amlodipine is available in tablet form in strengths ranging from 2.5 to 10 mg. The recommended starting dose of amlodipine is usually 5 mg once daily, and the maximum dose is 10 mg once daily. amlodipine can be taken with or without food, but it should be taken simultaneously every day telmisartan is available in tablet form in strengths ranging from 20 to 80 mg. The recommended starting dose of telmisartan is usually 20 mg once daily, and the maximum dose is 80 mg once daily.

Telmisartan can be taken with or without food, but it should be taken simultaneously every day It is essential to take these medications exactly as the healthcare provider prescribes, even if the patient is feeling well. Abruptly stopping these medications may result in a rebound increase in blood pressure, which may lead to serious health consequences. If a dose is missed, it should be taken as soon as possible unless it is almost time for the next dose, in which case the missed dose should be skipped, and the regular dosing schedule resumed

Patient information leaflet

Generic Name: amlodipine/telmisartan

Pronounced: [ am-LOE-de-peen-and-TEL-me-SAR-tan]

Why do we use amlodipine/telmisartan?

amlodipine is a calcium channel blocker used to treat hypertension and angina (chest pain). It is often prescribed in combination with other medications for the treatment of hypertension, such as angiotensin-converting enzyme (ACE) inhibitors, diuretics, and beta-blockers.

telmisartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. It is often used with other medications, such as diuretics and calcium channel blockers, to lower blood pressure. In addition to its blood pressure-lowering effects, telmisartan has been shown to have anti-inflammatory and antioxidant properties, and it may have additional benefits for patients with cardiovascular disease.