- July 26, 2022
- Newsletter
- 617-430-5616
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Brand Name :
Prazin, Minipress, Prazo
Synonyms :
prazosin
Class :
Anti-hypertensives and Alpha-Blockers
Brand Name :
Prazin, Minipress, Prazo
Synonyms :
prazosin
Class :
Anti-hypertensives and Alpha-Blockers
Dosage Forms & Strengths
capsule
1mg
2mg
5mg
Initial:
1
mg
Orally
8 - 12
hrs
Maintenance: 6-15 mg once a day or divided 2 to 3 times a day alternatively
off-label
Initial:
0.5
mg
Orally
every 12 hrs
Maintenance: 2 mg orally 12 hours
Dosage Forms & Strengths
capsule
1mg
2mg
5mg
Off-label:
Initial: 0.05-0.1 mg/kg orally once a day
may decrease the diagnostic effect when combined with benzylpenicilloyl polylysine
may have an increased hypertensive effect when combined with alpha1-blockers
may have an increased hypotensive effect when combined with calcium channel blockers
may have an increased hypotensive effect when combined with calcium channel blockers
may have an increased hypotensive effect when combined with calcium channel blockers
may have an increased hypotensive effect when combined with calcium channel blockers
may have an increased hypotensive effect when combined with calcium channel blockers
may enhance the antihypertensive effect of other alpha1-Blockers
may enhance the antihypertensive effect of other alpha1-Blockers
may enhance the antihypertensive effect of other alpha1-Blockers
may enhance the antihypertensive effect of other alpha1-Blockers
may enhance the antihypertensive effect of other alpha1-Blockers
may increase the hypertensive effect of Monoamine Oxidase inhibitors
may decrease the vasoconstriction effects
alpha1-Blockers may reduce the vasoconstricting effect of alpha-/Beta-agonist
may enhance the orthostatic hypotensive effect of alpha1-blockers
may enhance the orthostatic hypotensive effect of alpha1-blockers
may enhance the orthostatic hypotensive effect of alpha1-blockers
may enhance the orthostatic hypotensive effect of alpha1-blockers
may enhance the orthostatic hypotensive effect of alpha1-blockers
may enhance the hypotensive effect of calcium channel blockers
may enhance the hypotensive effect of calcium channel blockers
may enhance the hypotensive effect of calcium channel blockers
may enhance the hypotensive effect of calcium channel blockers
may enhance the hypotensive effect of calcium channel blockers
alpha1-Blockers may enhance the hypotensive effect of phosphodiesterase 5 Inhibitors
alpha1-Blockers may enhance the hypotensive effect of phosphodiesterase 5 Inhibitors
alpha1-Blockers may enhance the hypotensive effect of phosphodiesterase 5 Inhibitors
may decrease the constriction effects of alpha-1 agonist
may decrease the constriction effects of alpha-1 agonist
hydrocodone/chlorpheniramine/pseudoephedrine
may decrease the vasoconstriction effects of alpha/beta agonists
may increase the bradycardia effect
may enhance the hypotensive effect of Alpha1-Blockers
may enhance the hypotensive effect of Alpha1-Blockers
may enhance the hypotensive effect of Alpha1-Blockers
may enhance the hypotensive effect of Alpha1-Blockers
may enhance the hypotensive effect of Alpha1-Blockers
acrivastine and pseudoephedrine
may increase the vasoconstrictive effect of alpha/beta agonists
may increase the hypotensive effect of calcium channel blockers
may increase the hypotensive effect of calcium channel blockers
may enhance the orthostatic effect of beta blockers
may increase the effect of alpha1-blockers
may increase the effect of alpha1-blockers
may increase the effect of alpha1-blockers
may increase the effect of alpha1-blockers
may increase the effect of alpha1-blockers
may increase the effect of alpha1-blockers
may decrease the vasoconstricting effect of Alpha-/Beta-Agonists
Adverse drug reactions:
Frequency defined
1-10%
Drowsiness
Dizziness
Frequency Not Defined
Edema
Orthostatic hypotension
Syncope
Fever
Vomiting
Abnormal liver function tests
Impotence
Pancreatitis
Urinary incontinence
Rash
Abdominal discomfort/pain
Diarrhea
Pregnancy warnings:
AU TGA pregnancy category: B2
US FDA pregnancy category: C
Breastfeeding warnings:
The release of the drug into the human breastmilk is known
Pregnancy Categories:
Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.
Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits
Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: prazosin
Pronounced: PRAZ-oh-sin
Why do we use prazosin?
prazosin is an anti-hypertensive drug belonging to the subclass alpha-blocker used to treat hypertension. It mainly helps decrease high blood pressure and helps from the risk of heart attacks, strokes, and kidney diseases.