- March 15, 2022
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Brand Name :
Sajazir, Firazyr
Synonyms :
icatibant
Class :
Hereditary angioedema drugs, Immunomodulators
Dosage Forms & Strengths
Injection-SC
30mg (10 mg/mL)
3 mL (30 mg) subcutaneously (SC); if response is insufficient or clinical signs recur, additional 30-mg injections at least 6 hours apart may be given
icatibant may reduce the antihypertensive effect of ACE inhibitors
icatibant may reduce the antihypertensive effect of ACE inhibitors
icatibant may reduce the antihypertensive effect of ACE inhibitors
icatibant may reduce the antihypertensive effect of ACE inhibitors
icatibant may reduce the antihypertensive effect of ACE inhibitors
Icatibant may diminish the effect of ACE Inhibitors
Icatibant may diminish the effect of ACE Inhibitors
Icatibant may diminish the effect of ACE Inhibitors
Icatibant may diminish the effect of ACE Inhibitors
it may increase the bradycardic effect of other bradycardia-causing agents
it may increase the bradycardic effect on other Bradycardia-Causing Agents
it may increase the bradycardic effect on other Bradycardia-Causing Agents
Adverse drug reactions
Frequency Defined
>10%
Injection site reactions
1-10%
Transaminase increased (4%)
Pyrexia (4%)
Dizziness (3%)
Pregnancy warnings:
AU TGA pregnancy category: C
US FDA pregnancy category: Not assigned.
Lactation:
The drug excretion in breastmilk is unknown.
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
Category B: there was no evidence of risk to the fetus in animal studies, and there were no enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Patient Information Leaflet
Generic Name: icatibant
Why do we use icatibant?
icatibant is a Immunomodulators used to treat Hereditary Angioedema.
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