Mechanism of action
The action of cabergoline stimulates the dopamine receptors in the pituitary gland, reducing the secretion of prolactin from the lactotroph cells. This reduction in prolactin secretion is responsible for the drug’s therapeutic effects in hyperprolactinemia and other conditions associated with elevated prolactin levels
In Parkinson’s disease, cabergoline works by enhancing the effect of dopamine in the brain and improving the symptoms of the disease, such as tremors, rigidity, and bradykinesia
Spectrum
It has a broad spectrum of activity, which is why it treats various conditions. In addition to hyperprolactinemia and Parkinson’s disease, cabergoline has also been used to treat infertility, uterine fibroids, and obsessive-compulsive disorder