rivastigmine

DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions:  

Frequency Defined  

>10%:  

Weight loss   

Abdominal pain   

anorexia   

diarrhea    

nausea   

vomiting  

Application site erythema  

Agitation   

dizziness   

headache    

falling  

Tremor   

1-10%:  

Bradycardia    

hypertension   

syncope  

Diaphoresis  

Dehydration   

Decreased appetite   

Urinary incontinence   

urinary tract infection   

Abnormal gait  

aggressive behavior   

anxiety   

Asthenia   

bradykinesia   

<1%:  

Atrial fibrillation  

atrioventricular block  

Dystonia  

Post marketing:  

Tachycardia  

Allergic dermatitis   

Stevens-Johnson syndrome  

urticaria  

Severe vomiting  

Pregnancy warnings:    

Pregnancy Category: N/A 

Breastfeeding warnings: 

The release of the drug into the human breastmilk is unknown  

Pregnancy Categories:      

• Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first trimester or the later trimester      
• Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women      
• Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women      
• Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits      
• Category X: Drugs listed in this category outweigh risks over benefits. Hence these categories of drugs need to be avoided by pregnant women      
• Category N: There is no data available for the drug under this category     

 

Patient Information Leaflet  

Generic Name: rivastigmine 

Pronounciation: riv-uh-STIG-meen 

Why do we use rivastigmine? 

rivastigmine belongs to the class anticholinesterases and irreversible anticholinesterases used to treat alzheimer’s disease and parkinson’s disease