cariprazine

DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions:   

>10%  

Schizophrenia  

Parkinsonism (13-18%)  

Akathisia (9-14%)  

Insomnia (11-13%)  

Headache (9-18%)  

Bipolar mania  

Parkinsonism (21-26%)  

Constipation (6-11%)  

Akathisia (20-21%)  

Extrapyramidal symptoms (41-45%)  

Nausea (11-13%)  

Headache (13-14%)  

1-10%  

Decreased appetite (>1%)  

Schizophrenia  

Nausea (5-8%)  

Anxiety (3-6%)  

Dizziness (3-5%)  

Agitation (3-5%)  

Diarrhea (1-5%)  

Toothache (3-6%)  

Hypertension (2-7%)  

Abdominal pain (3-7%)  

Constipation (6-10%)  

Vomiting (4-5%)  

Pain in extremity (2-4%)  

Cough (1-4%)  

Somnolence (5-10%)  

Restlessness (4-6%)  

Dyspepsia (4-5%)  

   

Pregnancy warnings:     

US FDA pregnancy category: N/A 

Lactation: 

Excreted into human milk is UNknown  

Pregnancy Categories:       

Category A: Satisfactory and well-controlled studies show no risk to the fetus in the first or later trimester.       

Category B: No evidence shown of risk to the fetus found in animal reproduction studies, and there are not enough studies on pregnant women       

Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for a result in humans must take care of potential risks in pregnant women       

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.       

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.       

Category N: There is no data available for the drug under this category 

Patient Information Leaflet    

Generic Name: cariprazine 

Why do we use cariprazine? 

cariprazine are an atypical antipsychotic used to treat Bipolar I Disorder and schizophrenia.