potassium chloride

medtigo

potassium chloride

Brand Name :

KDur, KCl, K10, Klor-Con M, KTab, MicroK, K8, Kaon Cl 10, Klotrix, Slow K

Synonyms :

potassium chloride

Class :

Electrolyte Supplements, Parenteral, Electrolytes

Action and Spectrum

Actions and Spectrum

In order to maintain healthy cell activity, neuron transmission, and muscle contraction, potassium chloride is a necessary mineral. potassium shortage is treated or avoided when potassium chloride is provided since it returns the body’s potassium levels too normal.

The spectrum of potassium chloride refers to the variety of medicinal uses and outcomes. The therapeutic range of this medication is rather limited and is mostly used to treat potassium abnormalities.

Dosing & Uses

Drug Interaction

Adverse Reaction

Frequency not defined 

Arrhythmias

Hyperkalemia

Dyspepsia

Vomiting

Nausea

Rash

Bleeding

Diarrhea

Post marketing reports

Hyponatremia

Abdominal pain/discomfort

Hyponatremic encephalopathy

Gastrointestinal obstruction

Perforation

Gastrointestinal ulceration

Flatulence

Gastrointestinal perforation

Black Box Warning

Black Box Warning

Only intravenous administration of concentrated potassium chloride injection should be used, and only after dilution.

The fast or bolus intravenous infusion of concentrated potassium chloride has been linked to fatalities and major adverse effects.

A regulated infusion device must be used to provide potassium chloride concentrated injection slowly after diluting it.

Contraindication / Caution

Contraindication/Caution:

Contraindication:

Hyperkalemia, or high blood potassium levels, should not be treated with potassium chloride since it can cause even higher potassium levels and potentially life-threatening cardiac problems.
potassium build-up may be more likely in people with end-stage renal disease or severe kidney failure. In these circumstances, potassium chloride should not be used.

Caution:

potassium chloride should only be used with caution and under medical supervision by people with mild to moderate renal impairment.
When taking potassium chloride, patients with specific cardiac problems such as heart failure or bradycardia (slow heart rate) should be properly watched because it can disrupt heart rhythm.
It is challenging for some people to absorb potassium if they have gastrointestinal issues such severe diarrhoea or bowel blockage.

Pregnancy / Lactation

Pregnancy warnings:   

Pregnancy category: N/A

Lactation: Excretion into human milk is unknown

Pregnancy Categories:       

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.

<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. 

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.

Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.

Category N: There is no data available for the drug under this category.

Pharmacology

Pharmacology

In order to sustain normal cell activity and electrolyte balance, potassium, a significant intracellular cation, is essential. In cases of hypokalemia (low potassium levels), potassium levels are restored with potassium chloride.

The production and transmission of nerve impulses and the contraction of muscles are both mediated by potassium ions (K+). They help sodium-potassium pumps function properly and maintain the electrochemical gradient across cell membranes.

Pharmacodynamics

The normal operation of excitable tissues, such as nerve cells, depends on potassium. It influences the creation and spread of action potentials as well as the resting membrane potential.

For skeletal, cardiac, and smooth muscles to contract properly, potassium is necessary. For muscle fibers to contract in a coordinated and efficient manner, enough potassium levels are necessary.

Pharmacokinetics

Absorption  

It is absorbed from the digestive tract when taken orally. Mostly in the small intestine, absorption takes place.

Distribution

With potassium present in both intracellular and extracellular compartments, potassium ions from potassium chloride are dispersed throughout the body. potassium ions can freely diffuse across cell membranes because they are very water soluble.

Metabolism

In the body, potassium chloride is not significantly metabolized. It is largely a source of potassium ions, which take part in a few physiological processes without significantly changing chemically.

Elimination and excretion

The kidneys are the main organs via which potassium is excreted. In those with healthy kidneys, extra potassium is excreted in the urine. Aldosterone, a hormone that encourages potassium excretion in the distal renal tubules, controls potassium excretion.

Adminstartion

Administration

In addition to oral tablets and extended-release tablets, potassium chloride can also be taken intravenously and as a powder for oral solution.

Patient Information Leaflet

Patient information leaflet

Generic Name: potassium chloride

Why do we use potassium chloride?

The main purposes of potassium chloride are the treatment and avoidance of hypokalemia, often known as potassium deficiency. Low levels of potassium in the body are restored with potassium chloride.

potassium chloride aids in bringing potassium levels back to normal, which supports healthy cellular activity and preserves electrolyte balance. In circumstances when there is an electrolyte imbalance, potassium chloride is frequently employed, especially when potassium levels are low.

potassium chloride

No data available for drug.

DRUG INTERACTION

potassium chloride

&

potassium chloride +

Contraindicated

Serious Use Alternative

Monitor Closely

Minor

potassium chloride

No data available for drug.

DRUG INTERACTION

potassium chloride

&

potassium chloride +

Contraindicated

Serious Use Alternative

Monitor Closely

Minor

medtigo

potassium chloride

Brand Name :

Synonyms :

Class :

Action and Spectrum

Dosing & Uses

Drug Interaction

Adverse Reaction

Black Box Warning

Contraindication / Caution

Pregnancy / Lactation

Pharmacology

Adminstartion

Patient Information Leaflet

CONTACT INFORMATION

ADDRESS

JOIN THE FASTEST GROWING HEALTHCARE COMMUNITY!

Download our APP

CONTACT INFORMATION

ADDRESS

Taking the Pain out of Your Career

DOWNLOAD APP