remifentanil

DRUG INTERACTION

Contraindicated  

Serious Use Alternative  

Monitor Closely  

Minor  

Adverse drug reactions  

Frequency Defined  

>10%  

Vomiting  

Nausea  

1-10%  

Skeletal muscle rigidity  

Hypotension  

Bradycardia   

Hypertension  

Respiratory depression  

Tachycardia  

Pregnancy warnings:   
AU TGA pregnancy category: C
US FDA pregnancy category: Not Assigned 

Lactation:  

Excreted into human milk is unknown  

Pregnancy Categories:        

Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.   

Category B: there was no evidence of risk to the fetus in animal studies, and there were no enough studies on pregnant women.  

Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.    

Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.    

Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.    

Category N: There is no data available for the drug under this category  

Patient Information Leaflet    

Generic Name: remifentanil 

Why do we use remifentanil?  

remifentanil is an Opioids (narcotic analgesics) used to treat or prevent pain during and after surgery.