ozanimod

medtigo

ozanimod

Brand Name :

Zeposia

Synonyms :

ozanimod

Class :

Sphingosine 1-Phosphate Receptor Modulators

Action and Spectrum

Actions and Spectrum:

It is used for the treatment of relapsing forms of multiple sclerosis (MS). Here’s some information about the actions and spectrum of ozanimod:

Action: ozanimod works by binding to specific receptors called sphingosine 1-phosphate receptors (S1PR) on the surface of immune cells. By binding to these receptors, ozanimod prevents the immune cells, particularly lymphocytes, from exiting the lymph nodes and entering the bloodstream. This action reduces the migration of immune cells to the central nervous system (CNS), which plays a role in the inflammatory processes associated with MS.
Spectrum of Activity: ozanimod is indicated for the treatment of relapsing forms of MS, which include relapsing-remitting MS (RRMS) and active secondary progressive MS (SPMS) with relapses. It is not recommended for use in other forms of MS, such as primary progressive MS (PPMS).

Dosing & Uses

Drug Interaction

Adverse Reaction

>10%:

Upper respiratory tract infection

<1%:

Bradycardia

Macular edema

Black Box Warning

Contraindication / Caution

Ozanimod is contraindicated in patients hypersensitive to the active ingredient.

Pregnancy / Lactation

Pregnancy consideration:

No data is available regarding any fetal defects caused due to drug intake during pregnancy.

Breastfeeding warnings:

No data is available regarding the excretion of the drug in breast milk.

Pregnancy category:

Category A: well-controlled and Satisfactory studies do not show risk to the fetus in the first/later trimester.       
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women       
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.      
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.       
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.       
Category N: There is no data available for the drug under this category

Pharmacology

Adminstartion

Patient Information Leaflet

Patient information leaflet:

Generic Name: ozanimod

Why do we use ozanimod?

ozanimod is used primarily for the treatment of relapsing forms of multiple sclerosis (MS). Here are some reasons why ozanimod may be prescribed.

Relapsing-Remitting Multiple Sclerosis (RRMS): ozanimod is approved for the treatment of relapsing-remitting MS, which is the most common form of MS. RRMS is characterized by periods of active disease (relapses) followed by periods of remission.
Active Secondary Progressive Multiple Sclerosis (SPMS) with Relapses: ozanimod is also approved for the treatment of active SPMS with relapses. SPMS is a stage of MS that follows the initial relapsing-remitting phase, where there is a gradual progression of disability over time.

ozanimod

No data available for drug.

DRUG INTERACTION

ozanimod

&

ozanimod +

Contraindicated

Serious Use Alternative

Monitor Closely

Minor

ozanimod

No data available for drug.

DRUG INTERACTION

ozanimod

&

ozanimod +

Contraindicated

Serious Use Alternative

Monitor Closely

Minor

medtigo

ozanimod

Brand Name :

Synonyms :

Class :

Action and Spectrum

Dosing & Uses

Drug Interaction

Adverse Reaction

Black Box Warning

Contraindication / Caution

Pregnancy / Lactation

Pharmacology

Adminstartion

Patient Information Leaflet

CONTACT INFORMATION

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