- March 15, 2022
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Brand Name :
Intelence
Synonyms :
etravirine
Class :
Antiviral agents and Anti-HIV (antiretroviral)
Dosage Forms & Strengths
Tablet, Oral:
25 mg
100 mg
200 mg
Note: use preferred in combination with other antiretroviral agents
Dosage Forms & Strengths
Tablet, Oral:
25 mg
100 mg
200 mg
Note: use preferred in combination with other antiretroviral agents
Refer to adult dosing
It may diminish the levels when combined with efavirenz by enhancing metabolism
It may diminish the effect when combined with irinotecan liposomal by affecting CYP3A4 metabolism
when both drugs are combined, there may be a decreased levels of serum concentration of etravirine
etravirine decreases the effect of ixazomib by altering intestinal/hepatic CYP3A4 enzyme metabolism
CYP3A strong enhancers of the small intestine may reduce the bioavailability of etravirine
etravirine decreases the effect of entrectinib by altering the intestinal or hepatic CYP3A4 enzyme metabolism
etravirine decreases the effect of encorafenib by altering the intestinal or hepatic CYP3A4 enzyme metabolism
rifabutin: they may diminish the serum concentration of etravirine
it may enhance the metabolism when combined with zuclopenthixol
etravirine: they may diminish the serum concentration of hormonal contraceptive
etravirine: they may diminish the serum concentration of hormonal contraceptive
etravirine: they may diminish the serum concentration of hormonal contraceptive
etravirine: they may diminish the serum concentration of hormonal contraceptive
could potentially lead to a reduction in the concentration serum of Hormonal Contraceptives
could potentially lead to a reduction in the concentration serum of Hormonal Contraceptives
could potentially lead to a reduction in the concentration serum of Hormonal Contraceptives
could potentially lead to a reduction in the concentration serum of Hormonal Contraceptives
when both drugs are combined, there may be a high metabolism of paclitaxel
etravirine decreases the effect of gefitinib by altering the intestinal/ hepatic CYP3A4 enzyme metabolism
it decreases the concentration of hormonal contraceptives in serum
may diminish the serum concentration of each other when combined
may diminish the serum concentration of Hormonal Contraceptives
may decrease the level by affecting the hepatic enzyme CYP3A4 metabolism
Frequency defined:
>10%
Skin rash
Increased serum cholesterol
1% to 10%:
Angina pectoris
Facial edema
Atrial fibrillation
Myocardial infarction
Syncope
Peripheral neuropathy
Abnormal dreams
Anxiety
Confusion
Drowsiness
Disorientation
Disturbance in attention
Nervousness
Hypoesthesia
Prurigo
Night sweats
Xeroderma
Diabetes
lipohypertrophy
pancreatitis
stomatitis
anorexia
constipation
flatulence
gastritis
Post-marketing:
Angioedema
Erythema multiforme
Hemorrhagic stroke
Rhabdomyolysis
Stevens-Johnson syndrome
Dress syndrome
Pregnancy consideration: Etravirine transfer across the human placenta.
Lactation: Etravirine can be present in breast milk.
Pregnancy category:
Patient information leaflet
Generic Name: Etravirine
Pronunciation: etravirine
Why do we use Etravirine?
It is used to treat viral infections such as HIV-1 infection.
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