Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Vistamycin, Ribocin, Ribomed, Ribostat, Ribotacin
Synonyms :
Ribostamicina, ribostamycin, Ribostamycine, Vistamycin, Ribostamycinum
Class :
Antibacterial agents, Aminoglycosdie antibiotic, Protein biosynthesis inhibitor
Brand Name :
Vistamycin, Ribocin, Ribomed, Ribostat, Ribotacin
Synonyms :
Ribostamicina, ribostamycin, Ribostamycine, Vistamycin, Ribostamycinum
Class :
Antibacterial agents, Aminoglycosdie antibiotic, Protein biosynthesis inhibitor
Dosage Forms & StrengthsÂ
Injectable SolutionÂ
0.5 gÂ
1.0 gÂ
It is a broad-spectrum antibiotic that is used in the treatment of bacterial infections, which is administered in 1 g injectable solution (IM/ IV)
Dose Adjustments
No established data for dose modifications in renal or hepatic impairment patients is available
Safety and efficacy are not seen in pediatricsÂ
Refer to the adult dosingÂ
the effectiveness of the BCG vaccine may be reduced with ribostamycin in combination
ribostamycin, when used with alendronic acid, can lead to a higher risk of nephrotoxicity and hypocalcemia
there is a higher risk of methemoglobinemia when used in combination with ribostamycin
the excretion rate of ribostamycin is reduced by abacavir, which results in higher serum concentration
the excretion rate of ribostamycin is reduced by acemetacin, which results in higher serum concentration
Actions and Spectrum:Â
Actions:Â
ribostamycin is a broad-spectrum aminoglycoside-aminocyclitol antibiotic isolated from streptomyces ribosidificus which binds to 30S and 50Ssubunit of bacterial ribosome where it leads to inhibition of protein synthesis by translocating peptidyl-tRNA from site A to site P which leads to altered interpretation of mRNA that makes impossible for the bacteria to make proteins that is required for its growth. It also inhibits activity of PDI by chaperone.Â
Spectrum:Â
ribostamycin is a broad-spectrum that are active against both gram positive and gram-negative bacteria which is isolated from streptomyces ribosidificus. It is used in the treatment for various bacterial infections in conditions such as sepsis, skin infections, lymphadenitis, osteomyelitis, laryngitis, tonsilitis, acute bronchitis, gonococcal infections, sinusitis naming a few. It is also used against HIV and is regarded as one of the important antimicrobials by WHO.Â
Frequency Not Defined Â
AnaphylaxisÂ
erythrodermaÂ
Black Box Warning:Â
Monitoring for the serious reactions such as nephrotoxicity and methemoglobinemia.Â
Contraindication/Caution:Â
ContraindicationsÂ
CautionsÂ
Pregnancy consideration:Â Â
No data is available regarding the administration of the drug during pregnancy.Â
Breastfeeding warnings:Â Â
No data is available regarding the excretion of drug in breast milk.Â
Pregnancy category:Â
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.   Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.   Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.   Â
Category N: No data is available for the drug under this category.Â
Pharmacology:Â
ribostamycin is a broad-spectrum aminoglycoside-aminocyclitol antibiotic isolated from streptomyces ribosidificus which binds to 30S and 50Ssubunit of bacterial ribosome where it leads to inhibition of protein synthesis thereby inhibiting bacterial growth. Â
Pharmacodynamics:Â
ribostamycin is a broad-spectrum aminoglycoside-aminocyclitol antibiotic isolated from streptomyces ribosidificus which binds to 30S and 50Ssubunit of bacterial ribosome where it leads to inhibition of protein synthesis by translocating peptidyl-tRNA from site A to site P which leads to altered interpretation of mRNA that makes impossible for the bacteria to make proteins that is required for its growth. It also inhibits activity of PDI by chaperone.Â
Pharmacokinetics:Â
AbsorptionÂ
After administered dose of IM or IV, ribostamycin is rapidly absorbed into systemic circulation.Â
DistributionÂ
ribostamycin has higher affinity towards high blood flow especially renal organs.Â
MetabolismÂ
Not metabolised extensively.Â
Elimination and ExcretionÂ
Renal clearance of the drug through glomerular filtration. Half-life is approx. 2 to 3 hours.Â
Administration:Â
ribostamycin is administered via IV or IM with dose which is prescribed by clinician depending on the clinical condition of patient which also involves divided doses to treat infections.Â
Patient information leafletÂ
Generic Name: ribostamycinÂ
Pronounced: rye-boh-stuh-mye-sinÂ
Why do we use ribostamycin?Â
ribostamycin is used in the treatment of infections both gram positive and gram negative also effective against drug resistance bacteria.  Â
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
