Microplastics and Misinformation: What Science Really Says
November 12, 2025
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Brand Name :
Priftin
Synonyms :
rifapentine
Class :
Antibiotics and Antitubercular Agents
Brand Name :
Priftin
Synonyms :
rifapentine
Class :
Antibiotics and Antitubercular Agents
Dosage Forms & StrengthsÂ
Tablet Â
150mgÂ
Dosage Forms & StrengthsÂ
Tablet Â
150mgÂ
Refer to adult dosingÂ
May decrease the diagnostic effect when combined with tuberculin Tests
it decreases the concentration of cabotegravir in the serum
It may diminish the effect when combined with lumateperone by affecting CYP3A4 metabolism
rifapentine decreases the effect of ixazomib by altering intestinal/hepatic CYP3A4 enzyme metabolism
may reduce the therapeutic efficacy of enzalutamide
may decrease the serum concentration of CYP2C9 substrates
may decrease the serum concentration of CYP2C9 substrates
is having an antagonistic effect over brentuximab vedotin by showing altered intestinal/hepatic CYP3A4 enzyme metabolism.
rifapentine decreases the effect of gefitinib by altering the intestinal/ hepatic CYP3A4 enzyme metabolism
Frequency Defined Â
>10% Â
Hyperuricemia Â
1-10% Â
Headache Â
Hypertension Â
Acne Â
Dizziness Â
Anorexia Â
Lymphopenia Â
Nausea/vomiting Â
Rash Â
Diarrhea Â
Neutropenia Â
Dyspepsia Â
Pruritus Â
Anemia Â
 Â
Pregnancy warnings:    Â
US FDA pregnancy category: CÂ
Lactation:  Â
Excreted into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.   Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.  Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.    Â
Category D: adequate data available with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.    Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.    Â
Category N: There is no data available for the drug under this categoryÂ
Patient information leafletÂ
Generic Name: rifapentineÂ
Why do we use rifapentine?Â
Rifapentine is an antibiotic that is used to treat certain types of bacterial infections. It is a member of the rifamycin class of antibiotics and works by inhibiting the synthesis of certain proteins that are required by bacteria for growth and reproduction. Rifapentine is mostly used to treat tuberculosis (TB), a serious infectious disease caused by the bacterium Mycobacterium tuberculosis. Â
It can be used as part of a combination therapy to treat active TB, or it can be used to prevent the development of active TB in people who have been exposed to the bacteria. Rifapentine is usually taken once a week, and it is usually taken in combination with other antibiotics to help reduce the risk of resistance developing.Â
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