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Brand Name :
Risofos, Resica
Synonyms :
risedronate/calcium/vitamin D3
Class :
Oteoporosis agent, Bisphosphonate
Dosage Forms & Strengths
Tablet (Kit)
35 mg/500 mg/0.25 mcg
(risedronate/calcium/vitamin D3)
Take one risedronate tablet on the first day, followed by one tablet of calcium/vitamin D3 for the next six days, and this cycle is repeated with the next treatment pack starting with the risedronate tablet
The tablet should be taken once a week on the same day
Not determined
Actions and Spectrum:
Risedronate/Calcium/Vitamin D3 is a combination drug. Risedronate is a bisphosphonate which suppresses osteoclast activity, strengthening bones and reducing fracture risk.
Calcium supports bone health, and Vitamin D3 helps in calcium absorption and muscle function to prevent falls.
Frequency not defined
Hypersensitivity reactions
Nausea
Angioedema
Oesophageal stricture
Atypical femoral fractures
Hypersensitivity reactions
Uveitis
Pruritus
Abdominal pain
Rash
Black box warning:
None
Contraindication/Caution:
Contraindications
Cautions
Pregnancy Warnings:
Pregnancy category: N/A
Lactation: Excretion of the drug into the human breast milk is unknown
Pregnancy categories:
Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.
Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.
Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology:
Risedronate has an affinity for bone hydroxyapatite crystals. Calcium helps to build and maintain bones. Vitamin D3 helps effectively absorb calcium in body.
Pharmacodynamics:
Limited information is available.
Pharmacokinetics:
Limited information is available on ADME.
Administration
It is taken orally. Take it at least 30 minutes before the first intake of food.
Patient information leaflet
Generic Name: risedronate/calcium/vitamin D3
Why do we use risedronate/calcium/vitamin D3?
Risedronate/calcium/vitamin D3 is a combination drug which is indicated in the treatment of bone-related conditions i.e., osteoporosis.
Osteoporosis is a disorder caused by weakening of bones.