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Brand Name :
Givaudan
Synonyms :
Sandalore, sandal pentanol
Class :
Emollients, Skin conditioning agent
Brand Name :
Givaudan
Synonyms :
Sandalore, sandal pentanol
Class :
Emollients, Skin conditioning agent
Dosage forms and strength
Hair conditioning
Sandalore is a synthetic sandalwood-like odorant used in cosmetics. It has already shown its effectiveness in wound repair and rejuvenating hair follicles in the pre-clinical study
Sandalore is a synthetic sandalwood-like odorant used in cosmetics. It has already shown its effectiveness in wound repair and rejuvenating hair follicles in the pre-clinical study
Not determined
GERIATRIC DOSING
Refer to adult dosing
Actions and spectrum:
Sandalore and its related substances are present in the skin and are involved in several different processes.
They stimulate keratinocytes and have a positive effect on cell migration, proliferation, and regeneration.
Frequency not defined
Mild skin irritation
Contact dermatitis
Severe irritation of eyes
Black box warning:
None
Contraindication/Caution:
None
Pregnancy Warnings:
Pregnancy category: N/A
Lactation: Excretion of the drug into the human breast milk is unknown
Pregnancy categories:
Category A: Satisfactory and well-controlled studies show no evidence of risk to the fetus in the first trimester or in the later trimester.
Category B: No evidence of risk to fetus found in animal reproduction studies and there are not enough studies on pregnant women.
Category C: Adverse effects on the fetus found with evidence in animal reproduction studies and no adequate evidence for an effect in humans, care must be taken for potential risks in pregnant women.
Category D: There is adequate data available with sufficient evidence of human fetal risk from various platforms, but despite potential risks may be used only in emergency cases for potential benefits.
Category X: Drugs listed in this category clearly outweigh risks over benefits. These category drugs should be prohibited for pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology:
Sandalore is a synthetic odorant of sandalwood. It is clinically relevant in human hair follicle organ culture.
Pharmacodynamics:
Sandalore is an agonist of the OR2AT4 olfactory receptor and induces strong calcium signals in human keratinocytes.
Pharmacokinetics:
Limited data is available.
Administration
It is applied topically as per advised.
Patient information leaflet
Generic Name: sandalore
Why do we use sandalore?
Sandalore is used to rejuvenate hair follicles as hair conditioning.
It is also used to heal wounds and treat seborrheic dermatitis and atopic dermatitis.
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