Microplastics and Misinformation: What Science Really Says
November 12, 2025
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Brand Name :
N/A
Synonyms :
saruplase
Class :
Thrombolytic agent
Brand Name :
N/A
Synonyms :
saruplase
Class :
Thrombolytic agent
Dosage Forms & StrengthsÂ
Intravenous solution Â
20 mgÂ
60 mgÂ
Administer dose of 20 mg as a bolus and then followed by dose of 60 mg infused over an hour
Not determined Â
Refer to adult dosingÂ
Actions and SpectrumÂ
The action of unglycosylated human-type high molecular weight single-chain urokinase-type plasminogen activator is primarily related to its ability to activate plasminogen. Â
Plasminogen is an inactive precursor that, when activated to plasmin, can break down fibrin clots into smaller fragments.
Frequency not defined Â
NoneÂ
Black Box WarningÂ
None
Contraindication/Caution:Â
NoneÂ
Pregnancy consideration:Â
Pregnancy category: N/AÂ
Lactation: Excretion into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology Â
NoneÂ
PharmacodynamicsÂ
None Â
PharmacokineticsÂ
Information not available on ADME.
AdministrationÂ
Administration of saruplase is not available.Â
Patient information leafletÂ
Generic Name: saruplaseÂ
Why do we use saruplase?Â
Saruplase used in treatment of acute myocardial infarction. Â
Saruplase is a safe and effective as a thrombolytic agent and successfully conducted with open-label Practical Applicability of Saruplase Study (PASS). Â
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