Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Xyrem
Synonyms :
Class :
CNS depressants, sedatives, and hypnotics
Brand Name :
Xyrem
Synonyms :
Class :
CNS depressants, sedatives, and hypnotics
Dosage Forms & Strengths
Oral solution, schedule III
500mg/ml
4.5
g
Solution
Orally
dose divided every 4 hours
2.25g half strength and 2.25g taken 2.5-4 hours later
increase up to 1.5g/night at weekly intervals
Do not exceed 9g/night
Oral solution, schedule III
500mg/ml
<7 years: Safety and efficacy not established
≥7 years
<20 kgs: Start with a lower dose
20 to <30kgs:
Initial dose- ≤1g orally/day
Maintenance dose- increase by 0.5g/dose
Maximum dose-3g/day
30 to <45kgs:
Initial dose-≤1.5g orally/day
Maximum dose- 3.75g/day
≥45 kgs:
Initial dose- ≤2.25g orally/day, divided into two doses
Maximum dose- 4.5g/day
It may enhance the effects when combined with a shepherd's purse by pharmacodynamic synergism
sodium oxybate and melatonin exhibit pharmacodynamic synergism, which results in the increased effects of each other
The effect of either of the drugs is increased due to pharmacodynamic synergism.
enhancement in activity of either of the drugs occurs due to pharmacodynamic synergistic effect when sodium oxybate is taken with papaverine
Frequency defined:
>10%
Dizziness
Headache
Pharyngitis
Nausea
Vomiting
Pediatric
Headache
Nausea
Vomiting
Enuresis
1-10%
Diarrhea
Feeling drunk
Pain
Peripheral edema
Anxiety
Muscle spasms
Dry mouth
Pediatric
Agitation
Paranoia
Psychosis
<1%
Agitation
Paranoia
Psychosis
Hallucinations
Post-marketing reports
Hangover
Nocturia
Blurred vision
Aggression
Pregnancy consideration: Insufficient data is available
Lactation: Excretion of the drug is unknown
Pregnancy category:
Patient information leaflet
Generic Name: sodium oxybate
Pronounced: [ SO-dee-um-OX-i-bate]
Why do we use sodium oxybate?
It is used to treat narcolepsy-related daytime sleepiness and cataplexy (sudden loss of muscle strength)
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