Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Dagenan, Piridazol, Concord 693, Coccoclase
Synonyms :
Sulfapyridine, sulphapyridine, sulfapyridine. Sulfapyridina, 2-sulfapyridine
Class :
Sulfonamide antibiotics/antibacterial/dermato logical agents
Brand Name :
Dagenan, Piridazol, Concord 693, Coccoclase
Synonyms :
Sulfapyridine, sulphapyridine, sulfapyridine. Sulfapyridina, 2-sulfapyridine
Class :
Sulfonamide antibiotics/antibacterial/dermato logical agents
Dosage Forms & Strengths
Tablet
250mg
500mg
250mg to 1g orally four times every 24 hours
Once the symptoms are improved, the dose may be reduced by 250mg to 500mg orally one time a day for every three days until the symptoms disappear.
Indications: This drug is used to treat a few skin disease
Dosage Forms & Strengths
This drug is not advised for children as Duhring’s disease typically does not affect pediatric patients.
Refer to adult dosing.
the rate of metabolism of abrocitinib may be reduced
the therapeutic activity of acarbose may be increased
the rate of metabolism of acenocoumarol may be reduced
the risk of methemoglobinemia may be increased
the therapeutic activity of acetohexamide may be increased
the therapeutic activity of albiglutide may be increased
the therapeutic activity of alogliptin may be increased
the rate of metabolism of alosetron may be reduced
the rate of metabolism of aminophenazone may be reduced
the rate of metabolism of amitriptyline may be reduced
the rate of metabolism of amprenavir may be reduced
the risk of methemoglobinemia may be increased
the risk of methemoglobinemia may be increased
the rate of metabolism of apixaban may be reduced
the rate of metabolism of asunaprevir may be reduced
the rate of metabolism of azelastine may be reduced
the risk of methemoglobinemia may be increased
the rate of metabolism of bexarotene may be reduced
the rate of excretion of benzylpenicillin may be reduced
the therapeutic activity of bexagliflozin may be increased
Actions and spectrum:
Sulfapyridine fights bacteria by stopping an enzyme crucial for making folic acid. Folic acid helps bacteria make DNA and RNA. Sulfapyridine blocks the enzyme, so bacteria can’t divide and multiply properly. As a result, it’s harder for bacteria to spread and grow.
Frequency not defined
Headache
Itching
Rashes on skin
Itching
Fever
Pale skin
Sore throat
Unusual tiredness
Blistering
Peeling
Yellow skin or eyes
Pain in muscles and joints
Swallowing difficulty
Burning micturition
Lower back pain
Diarrhea
Nausea
Vomiting
Loss of appetite
Black Box Warning
Keep away from children
Contraindication/Caution:
Contraindication:
Hypersensitivity
Caution:
Gum bleeding
Risk of infections
Severe sunburn
Kidney stones
Pregnancy consideration:
USFDA pregnancy category: Not assigned
Lactation:
This drug is known to pose a minimal risk to infants. Hence, the benefits and risks should be outweighed before suggesting sulfapyridine to lactating mothers.
Pregnancy category:
Category A: Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
<b>Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence, these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category
Pharmacology:
Sulfapyridine is a sulfonamide antibiotic. Sulfonamide antibiotics work against many types of bacteria. They are effective against both gram-positive and gram-negative bacteria.
Pharmacodynamics:
Sulfapyridine is part of sulfonamide antibiotics. These man-made drugs can stop bacterial growth. They work on both positive and negative gram bacteria. But, some bacterial strains may resist their effects. Sulfonamides block folic acid production in bacteria. This stops bacteria from growing and multiplying. They compete for a chemical called p-aminobenzoic acid. Without it, bacteria cannot make folic acid. So, they cannot grow or reproduce.
Pharmacokinetics:
Absorption
Generally, between 60-80% gets taken into the body.
Distribution
Half of the drug tends to be bound to proteins in the plasma. This binding happens. It can vary, but about fifty percent attaches.
Metabolism
Sulfapyridine undergoes hepatic metabolism
Excretion and elimination
Sulfapyridine is a drug. Once taken, it remains in the body. Time passes. Eventually, its quantity diminishes. A half-life measures this decrease. For sulfapyridine, half leaves within 6-14 hours. That’s the half-life range. So, the drug’s concentration in blood drops by 50% after administration, taking 6-14 hours.
Administration:
Take sulfapyridine orally with plenty of water to prevent renal stone formation.
Patient information leaflet
Generic Name: sulfapyridine
Why do we use sulfapyridine?
Sulfapyridine operates by stopping dihydropteroate synthase, a crucial bacterial enzyme for growth. This halts bacterial spread. It treats skin issues like dermatitis herpetiformis.
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