Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
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Brand Name :
Trapilet, Rocornal, Travisco
Synonyms :
trapidil
Class :
Antiplatelet Agent, Vasodilator
Brand Name :
Trapilet, Rocornal, Travisco
Synonyms :
trapidil
Class :
Antiplatelet Agent, Vasodilator
Dosage Forms & StrengthsÂ
Capsule Â
200 mgÂ
TabletÂ
200 mgÂ
Take a daily dose of 400 to 600 mg orally in divided doses
Not determinedÂ
Refer to adult dosingÂ
aminophenazone: it may increase the risk of bleeding with trapidil
aminosalicylic acid: it may increase the risk of bleeding with trapidil
aminophenazone: it may increase the risk of bleeding with trapidil
anagrelide: it may increase the risk of bleeding with trapidil
benoxaprofen: it may increase the risk of bleeding with trapidil
bivalirudin: it may increase the risk of bleeding with trapidil
blinatumomab: it may increase the risk of bleeding with trapidil
bortezomib: it may increase the risk of bleeding with trapidil
citalopram: it may increase the risk of bleeding with trapidil
cladribine: it may increase the risk of bleeding with trapidil
clofarabine: it may increase the risk of bleeding with trapidil
cyclophosphamide: it may increase the risk of bleeding with trapidil
Actions and SpectrumÂ
trapidil is a vasodilator and a platelet aggregation inhibitor. It is useful in preventing the formation of blood clots within arteries and reducing the risk of thrombotic events. This vasodilatory effect reduces peripheral resistance, which can help lower blood pressure.
Frequency not defined Â
None
Black Box WarningÂ
None
Contraindication/Caution:Â
Contraindication:Â
Caution:Â
Pregnancy consideration:Â
Pregnancy category: N/AÂ
Lactation: Excretion into human milk is unknown Â
Pregnancy Categories:        Â
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.Â
Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women. Â
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.Â
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.Â
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.Â
Category N: There is no data available for the drug under this category.Â
Pharmacology Â
trapidil possesses antiplatelet properties, thus it inhibits the aggregation and activation of blood platelets. Platelets have an important role in forming blood clots, and inhibiting their activity can help prevent thrombotic events.Â
PharmacodynamicsÂ
Vasodilation affects the arteries, resulting in reduced peripheral vascular resistance and decreased blood pressure.Â
PharmacokineticsÂ
Absorption  Â
trapidil absorbed from the gastrointestinal tract after oral administration.Â
DistributionÂ
trapidil is distributed throughout the body.Â
MetabolismÂ
trapidil undergoes metabolism in the liver.Â
Elimination and excretionÂ
trapidil is excreted from the body through renal route.
AdministrationÂ
trapidil is administered orally in the form of tablets and capsules. Â
Patient information leafletÂ
Generic Name: trapidilÂ
Why do we use trapidil?Â
trapidil used in the management of ischemic heart disease. Â
trapidil is beneficial for individuals with peripheral arterial disease.
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