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Brand Name :
TCEL lotion
Synonyms :
triethyl citrate/ethyl linoleate
Class :
Pharmaceutic acid (Plasticizer/emollient)
Brand Name :
TCEL lotion
Synonyms :
triethyl citrate/ethyl linoleate
Class :
Pharmaceutic acid (Plasticizer/emollient)
Dosage Forms & Strengths
Solution (topical)
0.5%
1%
25 mL
Safety and efficacy are not seen in pediatrics
Refer to the adult dosing
Actions and Spectrum:
Actions:
Triethyl citrate comes from citric acid. It makes things flexible, so it’s used as a plasticizer. For pharmaceuticals, it coats tablets and capsules. In cosmetics, it goes into perfumes and hair products. Ethyl linoleate is made from linoleic acid. Its purpose is moisturizing the skin. Skincare products and beauty items contain it. It hydrates skin, improving texture and leaving it soft, nourished.
Spectrum:
A new lotion containing triethyl citrate and ethyl linoleate works fast. It treats mild and moderate acne pimples well, inflamed or not. The lotion is gentle on skin. It controls oily skin too. This lotion offers a nice alternative to treat acne without antibiotics.
Frequency defined
>10%
Erythema (20%)
Burning (33.3%)
Dry skin (30%)
Pruritis (40%)
1-10 %
Flare-up (6%)
Black Box Warning:
Upon noticing redness, itching or irritation after applying the lotion, stop using it right away. Consult a doctor without delay, if such symptoms occur.
Contraindication/Caution:
Contraindications
Cautions
Pregnancy consideration:
No data is available regarding the administration of the drug during pregnancy.
Breastfeeding warnings:
No data is available regarding the excretion of drug in breast milk.
Pregnancy category:
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology:
Triethyl citrate/ethyl linoleate (TCEL) displays hopeful qualities for acne therapy. It minimizes skin lesions promptly, while causing few adverse reactions and low likelihood of resurgence. Contrasting with antibiotics, TCEL averts promoting bacterial resistance. These attributes render TCEL a favored choice for acne treatment due to its efficacy, swift action, tolerability, and infrequent recurrence rates.
Pharmacodynamics:
Drugs used for acne fight the condition via several ways. Some antibacterial acne medicines stop microbial proteins from forming. Anti-keratinization acne medications prevent skin follicles from getting clogged. Meanwhile, anti-inflammatory acne medicines reduce redness and swelling from acne lesions. Each type works in slightly different ways. Yet together, they combat the causes of acne.
Pharmacokinetics:
Limited data is available
Administration:
Apply TCEL lotion using these simple steps. First, cleanse and dry your skin thoroughly. Next, apply a thin layer onto acne spots. Massage gently until absorbed, but don’t let it touch your eyes or mouth. Use it once or twice daily as directed by your healthcare provider or the product label. Consistency is key for optimal outcomes, so keep up with your routine.
Patient information leaflet
Generic Name: triethyl citrate/ethyl linoleate
Pronounced: try-ETH-il SIT-rayt/ETH-il LEE-noh-leet
Why do we use triethyl citrate/ethyl linoleate?
Triethyl citrate/ethyl linoleate (TCEL) offers key benefits in treating acne vulgaris. Unlike antibiotics, it avoids contributing to bacterial resistance – a major plus. TCEL effectively reduces acne lesions, acts quickly, and has minimal side effects. This makes it a favorable acne management option. What’s more, TCEL therapy has a low relapse rate. So, it’s an effective, sustainable acne treatment approach that shows promise.
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