Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study
November 7, 2025
Free CME credits
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
Brand Name :
Actifed DM sugar-free
Synonyms :
triprolidine/dextromethorphan
Class :
Cough and cold preparations
Brand Name :
Actifed DM sugar-free
Synonyms :
triprolidine/dextromethorphan
Class :
Cough and cold preparations
Dosage Forms & Strengths
Syrup
triprolidine/dextromethorphan
{(1.25mg/5ml)/10 mg}
Shake the bottle well before use and take oral dose as per physicians advised
Dosage Forms & Strengths
Syrup
triprolidine/dextromethorphan
{(1.25mg/5ml)/10 Mg}
For 13 to 18 years old:
Shake the bottle well before use and take oral dose as per physicians advised
Refer to adult dosing
Actions and Spectrum
triprolidine is an antihistamine. It works by blocking the effects of histamine, a chemical released by the body in response to allergens.
By blocking histamine, triprolidine can relieve symptoms associated with allergies, such as sneezing, runny nose, itchy or watery eyes, and itching of the throat or nose.
dextromethorphan is a cough suppressant. It works on the cough centre in the brain to reduce the urge to cough. It’s commonly used to relieve dry, non-productive coughs.
Frequency not defined
Blurred vision
Nausea
Vomiting
Trouble sleeping
Drowsiness
Dizziness
Headache
Black Box Warning
None
Contraindication/Caution:
Contraindication:
Caution:
Pregnancy consideration:
Pregnancy category: N/A
Lactation: Excretion into human milk is unknown
Pregnancy Categories:
Category A: well-controlled and Satisfactory studies show no risk to the fetus in the first or later trimester.
<b>Category B: there was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Pharmacology
triprolidine works by blocking the effects of histamine. It clashes with histamine for binding to H1 receptors on target cells, preventing histamine-induced responses.
dextromethorphan acts centrally in the brain to suppress the cough reflex. It does not have the addictive or analgesic properties associated with opioid-based cough suppressants.
Pharmacodynamics
triprolidine’s pharmacodynamic effect consists of the reduction of symptoms associated with allergies.
It also shows the side effect of central nervous system (CNS) depression, which can cause drowsiness and sedation.
dextromethorphan’s pharmacodynamic effect is the suppression of coughing. It reduces the urge to cough, providing relief from dry, non-productive coughs.
Pharmacokinetics
Absorption
triprolidine/dextromethorphan is well-absorbed when taken orally.
Distribution
triprolidine/dextromethorphan is distributed throughout the body, including to target tissues.
Metabolism
triprolidine/dextromethorphan undergoes metabolism in the liver, by cytochrome P450 enzymes.
Elimination and excretion
triprolidine/dextromethorphan are eliminated through the kidneys.
Administration
triprolidine/dextromethorphan is a combination drug available in the form of syrup and tablets/capsules for oral intake.
Patient information leaflet
Generic Name: triprolidine/dextromethorphan
Why do we use triprolidine/ dextromethorphan?
triprolidine/dextromethorphan is a combination drug used for the temporary relief of cough, sneezing, or runny nose due to the common cold and hay fever. triprolidine/dextromethorphan is a combination drug commonly used to relieve symptoms associated with allergies and coughs.
Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.
On course completion, you will receive a full-sized presentation quality digital certificate.
A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.
When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.
