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Brand Name :
Tropisetron hydrochloride
Synonyms :
tropisetron
Class :
Antiemetic and selective 5-HT3 antagonists
Brand Name :
Tropisetron hydrochloride
Synonyms :
tropisetron
Class :
Antiemetic and selective 5-HT3 antagonists
Dosage Forms & Strengths
Solution, Intravenous:
5 mg
2 mg
No dose recommended
Refer to adult dosing
May reduce the plasma concentration of tropisetron
May reduce the plasma concentration of tropisetron
CYP3A strong enhancers of the small intestine may reduce the bioavailability of tropisetron
it may diminish the excretion rate when combined with permethrin, resulting in an enhanced serum level
may have an increased serotonergic effect when combined with serotonergic agents
isoxicam may reduce the excretion rate of tropisetron, potentially leading to a higher serum level
combining tubocurarine with tropisetron may heighten the risk or severity of CNS depression
glycopyrrolate inhaled and formoterol
may increase the QTc interval when combined
the rate of excretion of tropisetron may be reduced
Frequency defined:
Significant:
QT prolongation
Headache
Dizziness
Abdominal pain
Visual hallucinations
Fatigue
Diarrhea
Anorexia
<1%:
Pregnancy consideration: Contraindicated for pregnant females
Lactation: The excretion of tropisetron in breast milk is not known.
Pregnancy category:
Patient information leaflet
Generic Name: Tropisetron
Pronounced: tropisetrone
Why do we use tropisetron?
Tropisetron is an antiemetic agent. Mostly used to treat nausea and vomiting before and after chemotherapy.
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