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Brand Name :
N/A
Synonyms :
Rock berry, Redberry, Bear grape, Sand berry, Arberry, Uva Ursi Folium, Common Bearberry, Bearberry
Class :
Urology, Herbals
Dosage forms and strengths
400 mg to 800 mg of dosage of arbutin is used in the products of uva ursi
Dosage of 3 gm in 150 mL in cold macerate or infusion for 3 to 4 times a day
400 mg to 840 mg of derivatives of hydroquinone
Not indicated
consuming uva ursi may increase the risk of hazardous blood levels of lithium, a medication used to treat bipolar mental health issue
Actions and Spectrum:
Actions:
The herb uva ursi can be used for different medicinal properties. The drug acts as urological & anti-infectious agents. The uva ursi leaves contain arbutin and hydroquinone, responsible for their antibacterial role. This can prevent the formation of germs in the urinary tract and treat UTIs and other urinary tract infections.
Spectrum:
Arbutin and ursolic acid, two phytochemicals found in uva ursi, which is used to treat urinary tract infections.
Black Box Warning:
Hydroquinone and uva ursi can damage the liver, thus it’s important to use them sparingly and under supervision.
Contraindication/Caution:
Contraindications
Hypersensitivity
Pregnancy & breastfeeding
Ulcers
Digestive disorders
Cautions
Liver disease
Kidney disease
Drug interactions
Pregnancy consideration:
Contraindicated
Breastfeeding warnings:
Contraindicated
Pregnancy category:
Category A: well-controlled and satisfactory studies show no risk to the fetus in the first or later trimester.
<b>Category B: There was no evidence of risk to the fetus in animal studies, and there were not enough studies on pregnant women.
Category C: There was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D: Adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X: Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: No data is available for the drug under this category.
Pharmacology:
The leaves of the uva ursi plant are used as medicine to treat conditions relating to the urinary tract, like irritation, infections, and elevated uric acid.
Pharmacodynamics:
The leaves of uva ursi contain compounds such as arbutin and hydroquinone, which contribute to their antibacterial properties. These substances play a role in inhibiting the growth of bacteria in the urinary tract, including in cases of UTI and other urinary ailments.
Pharmacokinetics:
Absorption
Uva ursi’s active compounds absorption occurs in the gastrointestinal tract.
Metabolism
The metabolism occurs in liver.
Excretion and elimination
The excretion occurs through the renal route.
Administration:
The drug is taken orally.
Patient information leaflet
Generic Name: uva ursi
Why do we use uva ursi?
The drug uva ursi contains arbutin, that have a property of diuretic & antiseptic which is used to treat infections of urinary tract.