Microplastics and Misinformation: What Science Really Says
November 12, 2025
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Brand Name :
Synonyms :
Apple peel extract
Class :
antitumor, anti-inflammatory
Brand Name :
Synonyms :
Apple peel extract
Class :
antitumor, anti-inflammatory
Suggested dosing
extract
10-40mg/kg
not indicated
choline magnesium trisalicylate
Nonsteroidal Anti-Inflammatory Agents: they may increase the toxic effect of salicylates
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may enhance the serum concentration when combined with lithium
may enhance the serum concentration when combined with lithium
may have an increased anticoagulant effect when combined with heparin
may have an increased anticoagulant effect when combined with heparin
may have an increased anticoagulant effect when combined with heparin
may diminish the effects of indomethacin by pharmacodynamic antagonism
may diminish the effects of indomethacin by pharmacodynamic antagonism
may increase the toxic effect
may Increase the adverse effect of NSAIDs
may Increase the adverse effect of NSAIDs
may increase the adverse effect of nonsteroidal anti-inflammatory agents
may increase the nephrotoxic effect of nonsteroidal anti-inflammatory agents
may increase the adverse effect of nonsteroidal anti-inflammatory agents
may increase the anticoagulant effect of nonsteroidal anti-inflammatory agent
may decrease the antihypertensive effect of nonsteroidal anti-inflammatory agents
may diminish the effectiveness of reducing proteinuria when combined with sparsentan
may increase the toxic effect of salicylates
may increase the toxic effect of nonsteroidal anti-inflammatory agents
may have an increasingly adverse effect when combined with dabigatran etexilate
may have an increased anticoagulant effect when combined with heparin
may enhance the serum concentration when combined with lithium
may enhance the serum concentration when combined with methotrexate
may enhance the serum concentration when combined with pralatrexate
may have an increasingly adverse effect when combined with rivaroxaban
choline magnesium trisalicylate
may have an increasingly adverse effect when combined with salicylates
may have an increased antiplatelet effect when combined with NSAIDs
may have an increased antiplatelet effect when combined with NSAIDs
may have an increased antiplatelet effect when combined with NSAIDs
may have an increased antiplatelet effect when combined with NSAIDs
may have an increased antiplatelet effect when combined with NSAIDs
may have an increased nephrotoxic effect when combined with tenofovir products
aspirin: they may increase the toxic effect of nonsteroidal anti-inflammatory agents
may enhance the concentration of serum when combined with lithium
may diminish the excretion when combined with aminoglycosides
neomycin/polymyxin B/bacitracin topical
may diminish the excretion when combined with aminoglycosides
the antiplatelet effect of NSAIDs can be increased with combined SSRIs
the antiplatelet effect of NSAIDs can be increased with combined SSRIs
tenofovir disoproxil fumarate or tenofovir DFÂ
nephrotoxicity associated with tenofovir products may increase with NSAIDs when combined
may diminish the rate of excretion which results in a higher serum level
may enhance the serum concentration of each other when combined
may enhance the serum concentration of each other when combined
may enhance the serum concentration of each other when combined
may enhance the serum concentration of each other when combined
may enhance the serum concentration of each other when combined
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may have an increased anticoagulant effect when combined with vitamin k antagonists
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may have an increased anticoagulant effect when combined with heparin
may have an increased anticoagulant effect when combined with heparin
may have an increased anticoagulant effect when combined with heparin
may enhance the concentration of serum when combined with lithium
may enhance the concentration of serum when combined with lithium
may enhance the risk of hypertension when combined
may enhance the risk of hypertension when combined
may enhance the risk of hypertension when combined
may enhance the risk of hypertension when combined
may enhance the risk of hypertension when combined
may diminish the rate of excretion leading to a higher serum level
may diminish the rate of excretion leading to a higher serum level
may diminish the rate of excretion leading to a higher serum level
may diminish the rate of excretion leading to a higher serum level
may diminish the rate of excretion leading to a higher serum level
may diminish the effect of each other when combined
may diminish the effect of each other when combined
may diminish the effect of each other when combined
may diminish the effect of each other when combined
may diminish the effect of each other when combined
may have an increased antiplatelet effect when combined with NSAIDs
may have an increased antiplatelet effect when combined with NSAIDs
may have an increased antiplatelet effect when combined with NSAIDs
NSAIDs may enhance the risk of adverse/toxic effect of other NSAIDs
NSAIDs may enhance the risk of adverse/toxic effect of other NSAIDs
NSAIDs may enhance the risk of adverse/toxic effect of other NSAIDs
NSAIDs may enhance the risk of adverse/toxic effect of other NSAIDs
NSAIDs may enhance the risk of adverse/toxic effect of other NSAIDs
SSRIs increase the antiplatelet effect of NSAIDs
SSRIs increase the antiplatelet effect of NSAIDs
SSRIs increase the antiplatelet effect of NSAIDs
SSRIs increase the antiplatelet effect of NSAIDs
SSRIs increase the antiplatelet effect of NSAIDs
drugs that are eliminated by active tubular secretion should be avoided due to nephrotoxicity when taken along with nRTI, where these decrease renal function and increase tenofovir-related adverse effects by increasing its level in the body, which needs to be avoided
drugs that are eliminated by active tubular secretion should be avoided due to nephrotoxicity when taken along with nRTI, where these decrease renal function and increase tenofovir-related adverse effects by increasing its level in the body, which needs to be avoided
drugs that are eliminated by active tubular secretion should be avoided due to nephrotoxicity when taken along with nRTI, where these decrease renal function and increase tenofovir-related adverse effects by increasing its level in the body, which needs to be avoided
it increases the toxicity of NSAIDs
NSAIDs may enhance the risk of adverse/toxic effect of other NSAIDs
NSAIDs may enhance the risk of adverse/toxic effect of other NSAIDs
NSAIDs may enhance the risk of adverse/toxic effect of other NSAIDs
NSAIDs may enhance the risk of adverse/toxic effect of other NSAIDs
NSAIDs may enhance the risk of adverse/toxic effect of other NSAIDs
may increase the toxic effect of non-steroidal anti-inflammatory drugs
may increase the antiplatelet effect of nonsteroidal anti-inflammatory agents
may increase the adverse effect of nonsteroidal anti-inflammatory agents
may decrease the therapeutic effect of prostaglandins
may have an increasingly adverse effect when combined with NSAIDs
may have an increasingly adverse effect when combined with NSAIDs
it increases the toxicity of NSAIDs
may diminish the therapeutic efficacy of each other when combined
may diminish the therapeutic efficacy of each other when combined
may diminish the therapeutic efficacy of each other when combined
may diminish the therapeutic efficacy of each other when combined
may diminish the therapeutic efficacy of each other when combined
spironolactone and hydrochlorothiazide
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
may diminish the therapeutic efficacy of each other when used in combination
angiotensin II receptor blockers increase the toxicity of NSAIDs
angiotensin II receptor blockers increase the toxicity of NSAIDs
angiotensin II receptor blockers increase the toxicity of NSAIDs
angiotensin II receptor blockers increase the toxicity of NSAIDs
angiotensin II receptor blockers increase the toxicity of NSAIDs
NSAIDs increase the toxicity of bisphosphonate derivatives
NSAIDs increase the toxicity of bisphosphonate derivatives
NSAIDs increase the toxicity of bisphosphonate derivatives
NSAIDs increase the toxicity of bisphosphonate derivatives
may decrease the excretion of aminoglycosides
may decrease the excretion of aminoglycosides
may decrease the excretion of aminoglycosides
may decrease the excretion of aminoglycosides
may decrease the excretion of aminoglycosides
may enhance the adverse/toxic effect of bisphosphonate derivatives
may enhance the adverse/toxic effect of bisphosphonate derivatives
may enhance the adverse/toxic effect of bisphosphonate derivatives
may enhance the adverse/toxic effect of bisphosphonate derivatives
may reduce the therapeutic effect of prostaglandins
may reduce the therapeutic effect of prostaglandins
NSAIDs may diminish the effect of beta-blockers
NSAIDs may diminish the effect of beta-blockers
NSAIDs may diminish the effect of beta-blockers
NSAIDs may diminish the effect of beta-blockers
NSAIDs may diminish the effect of beta-blockers
may enhance the nephrotoxic effect of 5-Aminosalicylic Acid Derivatives
may enhance the nephrotoxic effect of 5-Aminosalicylic Acid Derivatives
may enhance the adverse/toxic effect of corticosteroids
may enhance the adverse/toxic effect of corticosteroids
may enhance the adverse/toxic effect of corticosteroids
may enhance the adverse/toxic effect of corticosteroids
may enhance the adverse/toxic effect of corticosteroids
may reduce the effect of loop diuretics
may reduce the effect of loop diuretics
may reduce the effect of loop diuretics
choline magnesium trisalicylate
may enhance the adverse effect of salicylates
may reduce the effect of beta-blockers
may reduce the effect of beta-blockers
may reduce the effect of beta-blockers
may reduce the effect of beta-blockers
may reduce the effect of beta-blockers
may reduce the effect of beta-blockers
may have an increased neuroexcitatory and/or seizure-potentiating effect when combined with quinolones
may have an increased neuroexcitatory and/or seizure-potentiating effect when combined with quinolones
may decrease the antihypertensive effect when combined with beta-blockers
may decrease the antihypertensive effect when combined with beta-blockers
may enhance the effect of anticoagulants
may enhance the effect of anticoagulants
may enhance the effect of anticoagulants
may enhance the effect of anticoagulants
may enhance the effect of anticoagulants
may reduce the antihypertensive effect
may reduce the antihypertensive effect
may increase the risk of adverse effects
may reduce the rate of excretion of aminoglycosides
neomycin/polymyxin B/bacitracin topical
may reduce the rate of excretion of aminoglycosides
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
It may increase the adverse effects when combined with Corticosteroids (Ophthalmic)
It may increase the adverse effects when combined with Corticosteroids (Ophthalmic)
It may increase the adverse effects when combined with Corticosteroids (Ophthalmic)
It may increase the adverse effects when combined with Corticosteroids (Ophthalmic)
It may increase the adverse effects when combined with Corticosteroids (Ophthalmic)
It may increase the adverse effects when combined with Corticosteroids (Ophthalmic)
It may increase the adverse effects when combined with Corticosteroids (Ophthalmic)
It may increase the adverse effects when combined with Corticosteroids (Ophthalmic)
It may increase the adverse effects when combined with Corticosteroids (Ophthalmic)
may increase the effect of anticoagulant activity
may increase the effect of anticoagulant activity
may increase the effect of anticoagulant activity
may increase the effect of anticoagulant activity
may increase the effect of anticoagulant activity
may decrease the antihypertensive effect when combined with beta-blockers
may decrease the antihypertensive effect when combined with beta-blockers
may decrease the antihypertensive effect when combined with beta-blockers
nonsteroidal anti-inflammatory agents: they may decrease the therapeutic effect when combined with thiazides
nonsteroidal anti-inflammatory agents: they may decrease the therapeutic effect when combined with thiazides
nonsteroidal anti-inflammatory agents: they may decrease the therapeutic effect when combined with thiazides
nonsteroidal anti-inflammatory agents: they may decrease the therapeutic effect when combined with thiazides
may diminish the effect of antihypertensive activity
may diminish the effect of antihypertensive activity
may diminish the effect of antihypertensive activity
may diminish the effect of antihypertensive activity
may diminish the effect of antihypertensive activity
Nonsteroidal Anti-Inflammatory Agents: they may increase the toxic effect of corticosteroids
Nonsteroidal Anti-Inflammatory Agents: they may decrease the therapeutic effect of Angiotensin II Receptor antagonist
Nonsteroidal Anti-Inflammatory Agents: they may decrease the therapeutic effect of Angiotensin II Receptor antagonist
Nonsteroidal Anti-Inflammatory Agents: they may decrease the therapeutic effect of Angiotensin II Receptor antagonist
Nonsteroidal Anti-Inflammatory Agents: they may decrease the therapeutic effect of Angiotensin II Receptor antagonist
Nonsteroidal Anti-Inflammatory Agents: they may decrease the therapeutic effect of Angiotensin II Receptor antagonist
Nonsteroidal Anti-Inflammatory Agents: they may decrease the therapeutic effect of Angiotensin-Converting Enzyme Inhibitors
Nonsteroidal Anti-Inflammatory Agents: they may decrease the therapeutic effect of Angiotensin-Converting Enzyme Inhibitors
Nonsteroidal Anti-Inflammatory Agents: they may decrease the therapeutic effect of Angiotensin-Converting Enzyme Inhibitors
Nonsteroidal Anti-Inflammatory Agents: they may decrease the therapeutic effect of Angiotensin-Converting Enzyme Inhibitors
Nonsteroidal Anti-Inflammatory Agents: they may decrease the therapeutic effect of Angiotensin-Converting Enzyme Inhibitors
may decrease the antihypertensive effect when combined with beta-blockers
may decrease the antihypertensive effect when combined with beta-blockers
may decrease the antihypertensive effect when combined with beta-blockers
may have an increasingly adverse effect when combined with NSAIDs
may have an increased hyperkalemic effect when combined with potassium salts
NSAIDs may increase the nephrotoxic effect of 5-aminosalicylic acid derivatives
NSAIDs may increase the nephrotoxic effect of 5-aminosalicylic acid derivatives
May increase the adverse/toxic effect of NSAIDs
May increase the adverse/toxic effect of NSAIDs
May increase the adverse/toxic effect of NSAIDs
May increase the adverse/toxic effect of NSAIDs
May increase the adverse/toxic effect of NSAIDs
may reduce the antihypertensive effect of beta-blockers
may reduce the antihypertensive effect of beta-blockers
may reduce the antihypertensive effect of beta-blockers
may reduce the antihypertensive effect of beta-blockers
may reduce the antihypertensive effect of beta-blockers
may decrease the absorption of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may diminish the diuretic effect of loop diuretics
may diminish the diuretic effect of loop diuretics
may diminish the diuretic effect of loop diuretics
may enhance the antiplatelet effect of NSAIDs
may enhance the antiplatelet effect of NSAIDs
may enhance the antiplatelet effect of NSAIDs
may enhance the antiplatelet effect of NSAIDs
may enhance the antiplatelet effect of NSAIDs
may increase the adverse/toxic effect of NSAIDs
they increase the toxicity of metformin
may decrease the therapeutic effect
may diminish the therapeutic effect
may increase the levels of serum concentration of vancomycin
may enhance the risk of adverse/toxic effect of NSAIDs
may enhance the risk of adverse/toxic effect of NSAIDs
may enhance the risk of adverse/toxic effect of NSAIDs
may enhance the risk of adverse/toxic effect of NSAIDs
may enhance the risk of adverse/toxic effect of NSAIDs
may diminish the diagnostic effect of macimorelin
may increase the anti-coagulant action of anti-coagulants
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may enhance the adverse/toxic effect of NSAIDs
may increase the nephrotoxic effect of nonsteroidal anti-inflammatory agents
may increase the adverse effect of nonsteroidal anti-inflammatory agents
may decrease the therapeutic effect of beta blockers
may increase the toxic effect of angiotensin receptor II blockers
may increase the toxic effect of angiotensin receptor II blockers
lisinopril/hydrochlorothiazideÂ
may increase the hyperkalemic effect of Angiotensin-converting enzyme inhibitors
eprosartan/hydrochlorothiazideÂ
may increase the nephrotoxic effect of thiazide and thiazide like diuretics
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the adverse effect of NSAIDs
may enhance the hypoglycemic effect of beta blockers
may enhance the toxic effect of corticosteroids
may decrease the antihypertensive effect when combined with aliskiren
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may diminish the excretion when combined with aminoglycosides
may have an increasingly adverse effect when combined with NSAIDs
may have an increasingly adverse effect when combined with bisphosphonate derivatives
may have an increasingly adverse effect when combined with bisphosphonate derivatives
may have an increasingly adverse effect when combined with bisphosphonate derivatives
may have an increasingly adverse effect when combined with bisphosphonate derivatives
may have an increasingly adverse effect when combined with bisphosphonate derivatives
may have an increasingly adverse effect when combined with deferasirox
may have an increased hyponatremic effect when combined with desmopressin
may enhance the serum concentration when combined with digoxin
may decrease the antihypertensive effect when combined with hydralazine
may increase the anti-coagulant effect of Anti-coagulants
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the antiplatelet effect
may increase the antiplatelet effect
may increase the antiplatelet effect
may increase the antiplatelet effect
may increase the antiplatelet effect
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
may increase the risk of adverse effects
omacetaxine: they may increase the toxic effect of Nonsteroidal Anti-Inflammatory Agents
sodium acid phosphates: they may increase the nephrotoxic effect of Nonsteroidal Anti-Inflammatory Agents
tacrolimus: they may increase the nephrotoxic effect of Nonsteroidal Anti-Inflammatory drugs
verteporfin: they may increase the serum concentration of Nonsteroidal Anti-Inflammatory Agents
estrogens esterified/methyltestosterone            Â
may increase the thrombogenic effect of estrogen derivatives
drospirenone/ethinyl estradiol/levomefolateÂ
may increase the hyperkalemic effect of Drospirenone-Containing Products
nonsteroidal anti-Inflammatory agents may strengthen the anticoagulant effects of anticoagulants
nonsteroidal anti-Inflammatory agents may strengthen the anticoagulant effects of anticoagulants
nonsteroidal anti-Inflammatory agents may strengthen the anticoagulant effects of anticoagulants
nonsteroidal anti-Inflammatory agents may strengthen the anticoagulant effects of anticoagulants
nonsteroidal anti-Inflammatory agents may strengthen the anticoagulant effects of anticoagulants
The effectiveness of prostaglandins (ophthalmic) may be reduced by the presence of nonsteroidal anti-Inflammatory agents (ophthalmic)
The effectiveness of prostaglandins (ophthalmic) may be reduced by the presence of nonsteroidal anti-Inflammatory agents (ophthalmic)
polyethylene glycol and electrolytesÂ
They may increase the nephrotoxic effect when combined with polyethylene Glycol-electrolyte Solution
may have an increasingly adverse effect when combined with NSAIDs
may have an increasingly adverse effect when combined with NSAIDs
may have an increasingly adverse effect when combined with NSAIDs
framycetin, dexamethasone, and gramicidinÂ
may increase the toxic effect of each other
cyproterone and ethinyl estradiolÂ
may increase the thrombogenic effect when combined
naftazone: they may increase the antiplatelet effect of Nonsteroidal Anti-Inflammatory Agents
tricyclic antidepressants: they may increase the toxic effect of Nonsteroidal Anti-Inflammatory Agents
tricyclic antidepressants: they may increase the toxic effect of Nonsteroidal Anti-Inflammatory Agents
tricyclic antidepressants: they may increase the toxic effect of Nonsteroidal Anti-Inflammatory Agents
tricyclic antidepressants: they may increase the toxic effect of Nonsteroidal Anti-Inflammatory Agents
may increase the nephrotoxic effect of nonsteroidal anti-inflammatory agents
may increase the adverse effect of NSAIDs
when combined, Bisphosphonate Derivative's side effects can be increased with NSAIDs
when combined, Bisphosphonate Derivative's side effects can be increased with NSAIDs
when combined, Bisphosphonate Derivative's side effects can be increased with NSAIDs
when combined, Bisphosphonate Derivative's side effects can be increased with NSAIDs
when combined, Bisphosphonate Derivative's side effects can be increased with NSAIDs
spironolactone and hydrochlorothiazide
antihypertensive actions of potassium-sparing diuretics can be reduced with combined NSAIDs
antihypertensive actions of potassium-sparing diuretics can be reduced with combined NSAIDs
antihypertensive actions of potassium-sparing diuretics can be reduced with combined NSAIDs
antihypertensive actions of potassium-sparing diuretics can be reduced with combined NSAIDs
antihypertensive actions of potassium-sparing diuretics can be reduced with combined NSAIDs
when combined, the antihypertensive effect of Beta-Blockers can be reduced with NSAIDs
may increase the toxic effect of each other when combined
may have an increasingly adverse effect when combined with NSAIDs
may have an increasingly adverse effect when combined with NSAIDs
may have an increased nephrotoxic effect when combined with NSAIDs
may have an increased nephrotoxic effect when combined with NSAIDs
may have an increased nephrotoxic effect when combined with NSAIDs
may have an increased nephrotoxic effect when combined with NSAIDs
may have an increased nephrotoxic effect when combined with NSAIDs
may enhance the renal tubular clearance for anionic drug competition
Actions and Spectrum:
Ursolic acid, a naturally occurring triterpenoid compound found in a variety of plants, has a broad spectrum of actions and effects, including:
not indicated
none
Contraindication / Caution:
Ursolic acid is generally considered safe when consumed in the typical amounts found in fruits and vegetables. However, concentrated supplement forms of ursolic acid come with specific contraindications and precautions to bear in mind:
Contraindications:
Precautions:
Pregnancy warnings:Â Â Â
Pregnancy category: N/A
Lactation:Â Excreted into human milk is unknown
Pregnancy Categories:
Category A:Â Studies that were well-controlled and met expectations revealed no risk to the fetus in either the first or second trimester.
Category B: There was a lack of studies on pregnant women and no evidence of risk to the fetus in animal experiments.
Category C:Â there was evidence of risk of adverse effects in animal reproduction studies, and no adequate evidence in human studies must take care of potential risks in pregnant women.
Category D:Â adequate data with sufficient evidence of human fetal risk from various platforms, but despite the potential risk, and used only in emergency cases for potential benefits.
Category X:Â Drugs listed in this category outweigh the risks over benefits. Hence these categories of drugs need to be avoided by pregnant women.
Category N: There is no data available for the drug under this category.
Patient information leaflet
Generic Name: ursolic acid
Why do we use ursolic acid?
Ursolic acid offers a range of potential health benefits, including:
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