- May 31, 2022
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Brand Name :
Fetroja
Synonyms :
cefiderocol
Class :
Cephalosporins, Other
Dosage Forms & Strengths
Injection, lyophilized powder of reconstitution
1g
Pyelonephritis:
2 g IV given every 8hrs for 7-14 days
Urinary Tract Infection:
2 g IV given every 8hrs for 7-14 days
Nosocomial Pneumonia:
2 g IV given every 8hrs for 7-14 days
Renal Dose Adjustments:
2 g IV every 6hrs CrCl at least 120 ml per minute
1.5 g IV every 8hrs estimated CrCl 30 to 59 ml per minute
1 g IV every 8hrs estimated CrCl 15 to 29 ml per minute
0.75 g IV every 12hrs estimated CrCl less than 15 ml per minute without intermittent hemodialysis
Liver Dose Adjustments:
No adjustment recommended
2
g
Intravenous (IV)
every 8 hrs
7 - 14
days
2
g
Intravenous (IV)
every 8 hrs
7 - 14
days
2
g
Intravenous (IV)
every 8 hrs
7 - 14
days
Dose Adjustments
Renal Dose Adjustments:
2 g IV every 6hrs CrCl at least 120 ml per minute
1.5 g IV every 8hrs estimated CrCl 30 to 59 ml per minute
1 g IV every 8hrs estimated CrCl 15 to 29 ml per minute
0.75 g IV every 12hrs estimated CrCl less than 15 ml per minute without intermittent hemodialysis
Liver Dose Adjustments:
No adjustment recommended
when both drugs are combined, there may be a reduced blood level of berotralstat
when both drugs are combined, there may be an increased risk of seizures
when both drugs are combined, there may be a reduced blood level of butorphanol
when both drugs are combined, there may be a reduced blood level of acalabrutinib
when both drugs are combined, there may be an increased risk of seizures
when both drugs are combined, there may be an increased risk or severity of adverse effects
when both drugs are combined, there may be an increased risk or severity of adverse effects
when both drugs are combined, there may be an increased risk or severity of adverse effects
cephalosporins increase the effect of anticoagulation of vitamin K antagonists
cephalosporins increase the effect of anticoagulation of vitamin K antagonists
cephalosporins increase the effect of anticoagulation of vitamin K antagonists
cephalosporins increase the effect of anticoagulation of vitamin K antagonists
cephalosporins increase the effect of anticoagulation of vitamin K antagonists
may enhance the nephrotoxic effect of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
may enhance the nephrotoxic effect of aminoglycosides
they increase the effect of nephrotoxicity of aminoglycosides
neomycin/polymyxin B/bacitracin topical
they increase the effect of nephrotoxicity of aminoglycosides
cephalosporins increase the nephrotoxicity of aminoglycosides
cephalosporins increase the nephrotoxicity of aminoglycosides
cephalosporins increase the nephrotoxicity of aminoglycosides
cephalosporins increase the nephrotoxicity of aminoglycosides
cephalosporins increase the nephrotoxicity of aminoglycosides
it increases the nephrotoxicity of cephalosporins
it increases the concentration of cephalosporins in the serum
may increase the nephrotoxic effect
may enhance the adverse/toxic effect of rifampin
It may enhance the risk of adverse effects when combined with Cephalosporins
when both drugs are combined, there may be an increased risk of seizures
Adverse drug reactions:
Frequency defined
>10%
Elevated liver tests
Hypokalemia
1-10%
Increased ALT
increased GGT
increased AST
abnormal hepatic function
Hypomagnesemia
Diarrhea
vomiting
nausea
constipation
Frequency not defined
Cholelithiasis
cholecystitis
gallbladder pain
Cholestasis
Decreased appetite
hypocalcemia
fluid overload
hyperkalemia
Abdominal pain
dry mouth
stomatitis
C difficile-associated diarrhea
oral candidiasis
Pregnancy warnings:
Breastfeeding warnings:
Pregnancy Categories:
Patient Information Leaflet
Generic Name: Cefiderocol (Rx)
Pronounced: SEF-i-DER-oh-kol
Why do we use Cefiderocol?
Cefiderocol is the cephalosporin antibiotic drug used to treat those who have developed pneumonia while being in a hospital or on the ventilator
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Founded in 2014, medtigo is committed to providing high-quality, friendly physicians, transparent pricing, and a focus on building relationships and a lifestyle brand for medical professionals nationwide.
MASSACHUSETTS – USA
60 Roberts Drive, Suite 313,
North Adams, MA 01247
MAHARASHTRA – INDIA
7, Shree Krishna, 2nd Floor,
Opp Kiosk Koffee,
Shirole Lane, Off FC Road,
Pune 411004, Maharashtra
