Association Between Patient-Physician Distance and Primary Care Access in Ontario: A Population-Based Cross-Sectional Study

Access to primary care is important in Canada. Approximately 2.3 million Ontarians lack access to a regular source of public funding through the Ontario Health Insurance Plan (OHIP). Ontario’s primary care has shifted to patient enrolment models, with 75% of the population assigned to family physicians. Geographic distance poses challenges, as many patients have links […]
New FDA Approval Marks Breakthrough for High-Risk Smoldering Myeloma Patients

The U.S. Food and Drug Administration (FDA) has approved Darzalex Faspro (daratumumab and hyaluronidase-fihj, Janssen Biotech, Inc.) to treat adults with high-risk smoldering multiple myeloma (SMM). This is the first FDA approval for this category of patients at high risk of developing active multiple myeloma. This was supported by the results of AQUILA (NCT03301220), an open-label study that […]
Mobile health education for salt reduction and hypertension prevention: effects on knowledge acquisition and behavioral change among Chinese third-grade students
Front Public Health. 2025 Oct 22;13:1600342. doi: 10.3389/fpubh.2025.1600342. eCollection 2025. ABSTRACT BACKGROUND AND AIMS: This study evaluates the impact of a comprehensive health education intervention delivered via a mobile application on health knowledge and behavior among third-grade students in Zhenjiang, Jiangsu Province, China. With increasing rates of non-communicable diseases, particularly hypertension among children, this intervention […]
Usability and User Experience of a Digital Platform Prototype (Healthy Bone) to Promote Pharmacological and Nonpharmacological Treatment in Patients With Osteoporosis: Mixed Methods Study
JMIR Form Res. 2025 Nov 7;9:e72468. doi: 10.2196/72468. ABSTRACT BACKGROUND: Osteoporosis-related fractures significantly impact older adults, often leading to disability and even premature death. While pharmacological and nonpharmacological interventions are widely recommended for managing osteoporosis, adherence to these interventions remains low. To address this challenge, we developed the Healthy Bone digital platform (desktop, mobile app, […]
Enablers, Challenges, and Lessons Learned From a Digital Health Intervention (Sehatmandi App) in Afghanistan: Qualitative Study
J Med Internet Res. 2025 Nov 7;27:e74923. doi: 10.2196/74923. ABSTRACT BACKGROUND: In low- and middle-income countries, maternal, newborn, and child health face significant challenges due to infrastructure limitations, access disparities, and service delivery inefficiencies. The Sehatmandi mobile health (mHealth) app was deployed in 2018 to address these issues across 189 health facilities in Afghanistan’s Bamyan […]
A novel mobile application to examine impaired vigilance through digital means
Sci Rep. 2025 Nov 7;15(1):39115. doi: 10.1038/s41598-025-23155-z. ABSTRACT The psychomotor vigilance task (PVT) is a three to thirty-minute test widely used to measure alertness and vigilance. However, only a few comprehensively validated PVTs are currently available through digital means, e.g., mobile devices. Thus, the present study aimed to investigate the usefulness of a novel three-minute […]
Knowledge transfer-driven estimation of knee moments and ground reaction forces from smartphone videos via temporal-spatial modeling of augmented joint kinematics
PLoS One. 2025 Nov 7;20(11):e0335257. doi: 10.1371/journal.pone.0335257. eCollection 2025. ABSTRACT The knee adduction and flexion moment provides critical information about knee joint health, while 3D ground reaction forces (GRFs) help identify force and energy characteristics for maneuvering the entire human body. Existing methods of acquiring joint moments and GRFs require expensive equipment, time-consuming pre-processing, and […]
Anthropometric Measurements as Predictors of Low Birth Weight Among Tanzanian Neonates: A Hospital-Based Study

Low birth weight (LBW) is defined as a neonatal birth weight below 2500 grams. It is a major worldwide health issue. It affects one-sixth of newborns, with the highest rates in Sub-Saharan Africa. LBW is a major cause of neonatal mortality and morbidity, which contributes to 60-80% of deaths. In Tanzania, the LBW rate has […]
From Erosion to Restoration: The ELR-Matrix Regenerates Human Enamel Structure and Function

Dental enamel is the hardest and most mineralized tissue in vertebrates. It is formed through the organized 3D assembly of amelogenin. It guides hierarchical nanocrystal growth, providing strength and resistance to thermal, physical, and chemical insults. This protective layer safeguards the teeth throughout life. However, enamel loss occurs due to trauma, acid erosion, or mechanical […]
Tele-exercise mobile app for patients with facial paralysis: development and usability study
BMC Neurol. 2025 Nov 5;25(1):454. doi: 10.1186/s12883-025-04403-1. ABSTRACT INTRODUCTION: Facial nerve paralysis is a neurological disorder in which the intentional movements of the patient’s facial muscles are completely or partially lost due to involvement of the seventh cranial nerve. Physiotherapy, especially exercise therapy plays an important role in restoring movement to the muscles. Thus, this […]


