FDA Greenlights First Subcutaneous Maintenance Dose of LEQEMBI® for Early Alzheimer’s
The U.S. Food and Drug Administration (FDA) has approved the Biologics License Application (BLA) for LEQEMBI® IQLIK™ (lecanemab-irmb), a once-weekly subcutaneous (SC) autoinjector intended for maintenance treatment of Alzheimer’s disease (AD). This device delivers 360 mg/1.8 mL (200 mg/mL) in approximately 15 seconds per injection. It is indicated for patients with early AD, including those […]
Understanding the Behavioral Determinants of First Responder App Adoption by Integrating Perspectives From the Unified Theory of Acceptance and Use of Technology and Health Belief Model: Cross-Sectional Survey
JMIR Hum Factors. 2025 Sep 9;12:e69934. doi: 10.2196/69934. ABSTRACT BACKGROUND: Out-of-hospital cardiac arrests (OHCAs) are a leading cause of death worldwide, yet first responder apps can significantly improve outcomes by mobilizing citizens to perform cardiopulmonary resuscitation before professional help arrives. Despite their importance, limited research has examined the psychological and behavioral factors that influence individuals’ […]
User Engagement With a Mobile Health App for People Living With HIV: Observational Study Based on an Engagement Evaluation Framework
J Med Internet Res. 2025 Sep 9;27:e78810. doi: 10.2196/78810. ABSTRACT BACKGROUND: Mobile health (mHealth) interventions can be effective for people living with HIV, who are sensitive to privacy breach risks. Understanding the perceived experiences of intervention participants can provide comprehensive insights into potential users and predict intervention effectiveness. Thus, it is necessary to plan engagement […]
Development of a Social Communication Intervention Mobile App for Adolescents With Autism Spectrum Disorder and Social Communication Disorder: Protocol for a Pilot Randomized Clinical Trial
JMIR Res Protoc. 2025 Sep 9;14:e66419. doi: 10.2196/66419. ABSTRACT BACKGROUND: Autism spectrum disorder (ASD) and social communication disorder (SCD) are neurodevelopmental disorders characterized by deficits in social communication that hinder social adaptation, with limited pharmacological options for therapy owing to the absence of identified biomarkers. Individuals with ASD or SCD require lifelong interventions tailored to […]
Measuring problematic smartphone use among students using the Smartphone Addiction Scale
S Afr Fam Pract (2004). 2025 Aug 29;67(1):e1-e10. doi: 10.4102/safp.v67i1.6120. ABSTRACT BACKGROUND: Problematic Smartphone Use (PSU) is a growing concern, particularly among university students, due to its potential negative impacts on mental health, academic performance, and daily functioning. Characterized by compulsive smartphone use, PSU is linked to anxiety, depression, and sleep disturbances. Understanding PSU in […]
The Brain’s Second Thoughts: How We Change Our Minds
Mathematicians and psychologists have been fascinated by the Monty Hall problem for many years. It is named after the presenter of the American game show Let’s Make a Deal. In this game, a player picks one of three doors—say, option B with a hidden prize. The host knows the location of the prize, then opens […]
Metabolic Adaptations in Cortical Glucose Utilization Driving Human Brain Tumor Growth
The glucose carbons in the human brain are responsible for important physiological functions such as neurotransmitter production and tricarboxylic acid (TCA) cycle oxidation. Gliomas, however, disrupt these processes by suppressing glucose metabolism and recycling alternative carbon sources to generate metabolites that support invasion and proliferation. The most common type of malignant brain tumors is gliomas, […]
Increasing Awareness and Early Detection of Common Skin Diseases in Indonesia Through an mHealth App: Protocol for an Awareness and Acceptability Study and Randomized Controlled Trial
JMIR Res Protoc. 2025 Sep 8;14:e64057. doi: 10.2196/64057. ABSTRACT BACKGROUND: Various media are used to enhance public understanding about diseases. While mobile health apps are widely used, there is little proof for using such apps to raise awareness of skin diseases. OBJECTIVE: We intend to develop an app, called DEDIKASI-app, to raise awareness of skin […]
Metastatic Breast Cancer mHealth App to Promote Patient-Provider Communication: Protocol for a Usability and Satisfaction Study
JMIR Res Protoc. 2025 Sep 8;14:e66050. doi: 10.2196/66050. ABSTRACT BACKGROUND: With the availability of more advanced and effective treatments, life expectancy has improved among patients with metastatic breast cancer (MBC), but this makes communication with their medical oncologist more complex. Some patients struggle to learn about their therapeutic options and to understand and articulate their […]
Smartphone usage habits among french nursing students: A monocentric mixed-methods study
Arch Psychiatr Nurs. 2025 Oct;58:151958. doi: 10.1016/j.apnu.2025.151958. Epub 2025 Jul 28. ABSTRACT BACKGROUND: Smartphones, first introduced in 1992 in the United States, have evolved into essential communication tools due to their convenience and increasing functionalities. Their widespread use has significantly impacted daily life, leading to various psychological and physical consequences, particularly among young adults. In […]
