Essential Medicines for 2025: Priorities in Selection and Use

Essential Medicines

The core list provides safe, effective, and economical medications for priority diseases, including the minimal medication requirements for a basic healthcare system. Priority diseases are selected based on their potential for safe and cost-effective treatment as well as their current and projected public health significance. A special restriction for use in children is indicated by […]

The Silent Spread of Chagas Disease in the United States

Spread of Chagas Disease

Chagas disease or American trypanosomiasis is caused by the parasite Trypanosoma cruzi. It can be transmitted congenitally, orally, and through the bite of an insect vector, most commonly the triatomine bug or kissing bug. The World Health Organization and Pan American Health Organization (PAHO) recognize 21 endemic countries in the Americas, excluding the United States. […]

Participants’ Perspectives on the iCareBreast Mobile-Based Perioperative Care Program for Women Undergoing Breast Cancer Surgery: Qualitative Process Evaluation

JMIR Hum Factors. 2025 Sep 10;12:e71686. doi: 10.2196/71686. ABSTRACT BACKGROUND: Breast cancer treatment, particularly during the perioperative period, is often accompanied by significant psychological distress, including anxiety and uncertainty. Mobile health (mHealth) interventions have emerged as promising tools to provide timely psychosocial support through convenient, flexible, and personalized platforms. While research has explored the use […]

Enhancing Adolescent Asthma Control and Self-Efficacy: A Decision Tree Analysis of a Mobile Health Application in a Randomized Controlled Trial

J Eval Clin Pract. 2025 Sep;31(6):e70266. doi: 10.1111/jep.70266. ABSTRACT AIMS AND OBJECTIVES: To evaluate the efficacy of YoungAsthma, a nurse-led, web-based mHealth intervention on asthma control and self-efficacy among adolescents with asthma utilizing decision tree analysis. BACKGROUND: Asthma is a prevalent chronic condition in pediatric populations, necessitating sustained management for optimal disease control. DESIGN: A […]

Usability and quality evaluation of the World Health Organization SkinNTDs app among frontline health workers in Cameroon: A mixed methods study

PLoS Negl Trop Dis. 2025 Sep 10;19(9):e0013461. doi: 10.1371/journal.pntd.0013461. eCollection 2025 Sep. ABSTRACT BACKGROUND: Originally adapted from a paper-based guide for skin-related neglected tropical diseases (NTDs), version 3.0.0 of the World Health Organization (WHO) SkinNTDs app aims to strengthen disease surveillance and frontline health worker capacity in NTD-endemic settings. Evidence on its usability in routine […]

Mobile application prototyping using Artificial Intelligence to support childhood tuberculosis diagnosis

Rev Bras Enferm. 2025 Sep 8;78(3):e20240398. doi: 10.1590/0034-7167-2024-0398. eCollection 2025. ABSTRACT OBJECTIVES: to develop a mobile application prototype using Artificial Intelligence (AI) to predict and support the diagnosis of pulmonary tuberculosis in children – TB Kids. METHODS: technological development research of the prototyping type, based on the Rational Unified Process model and its four stages: […]

Deep Learning-Based Pattern Recognition for Detecting Penile Abnormalities: Protocol for Developing a Mobile App for Circumcision Eligibility

JMIR Res Protoc. 2025 Sep 10;14:e65811. doi: 10.2196/65811. ABSTRACT BACKGROUND: Circumcision is a widely practiced procedure with cultural and medical significance. However, certain penile abnormalities-such as hypospadias or webbed penis-may contraindicate the procedure and require specialized care. In low-resource settings, limited access to pediatric urologists often leads to missed or delayed diagnoses. Artificial intelligence (AI)-based […]

Accuracy of smartphone photographs for detecting active carious lesions in orthodontic patients

Braz Oral Res. 2025 Sep 8;39:e069. doi: 10.1590/1807-3107bor-2025.vol39.069. eCollection 2025. ABSTRACT Advancements in digital media have driven the study and use of photographic records as a diagnostic method for carious lesions, with smartphone images being widely utilized across various health fields. This study aimed to evaluate the diagnostic accuracy of smartphone photography for detecting active […]

Novel Combination Therapy with Testosterone and Recombinant Human Growth Hormone in Facioscapulohumeral Muscular Dystrophy

Facioscapulohumeral muscular dystrophy (FSHD) is a common type of adult-onset muscular dystrophy. It is characterized by progressive muscle weakness and atrophy. It may lead to functional decline, impaired ambulation, and decreased quality of life. Currently, there are no approved treatments to reverse or prevent muscle weakness or impairment in FSHD. In healthy individuals, combined administration […]

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