Study Reveals Uromune Vaccine’s Long-Term Efficacy Against UTIs

Urinary tract infection (UTI) is known as an infection within the urinary system (kidneys, bladder, ureters and urethra). UTI is very common as it affects half of women and one-fifth of men. It usually affects people of old age and increases severe health risks such as irregular heartbeat, high blood pressure, and lethal falls. Every year, 150,000 people get hospitalized, and 6,000 people die because of it.  

However, the vaccine Uromune can be a life savior for people suffering from this painful infection. This pineapple-flavored oral spray needs to be sprayed under the tongue. This vaccine contains 4 most common bacteria that cause UTIs, such as Klebsiella pneumoniae, Escherichia coli, Enterococcus Faecalis, and Proteus vulgaris. It is effective for 9 years and reduces the chances of hospitalization.   

Researchers from the Berkshire NHS Foundation Trust researched to understand the effectiveness of this vaccine. Dr Bob Yang led this research, which involved 89 people who had recurrent UTIs. These patients were asked to take this vaccine every day for 3 months and followed up by clinicians over nine years.   

When researchers observed the collected data, they found that 48% of the participants were completely infection-free during these nine years of follow-up sessions. The average infection-free period was 54.7 months. It was 56.7 months for women and 44.3 months for men. This difference of 1 year shows that the Uromune vaccine is more beneficial to women than men. 40% of the participants chose to get a second dose of the Uromune vaccine after one or two years. This shows the effectiveness and acceptance of the vaccine.  At present, healthcare professionals suggest some antibiotics to treat ongoing and recurrent UTIs. However, antibiotic treatment is less effective as it increases antibiotic-resistant infections.   

As this research shows the effectiveness of the Uromune vaccine in treating UTIs, healthcare professionals should suggest this vaccine to reduce the risk of hospitalization and death. Even though the results of this research are positive, there is a need for further research. Healthcare professionals should make some effective strategies for preventing UTIs as the number is on the rise.   

Reference Link:   

https://metro.co.uk/2024/04/07/game-changing-uti-vaccine-prevents-infections-nine-years-20602396/