Coronary CT Angiography

Updated : April 28, 2025

Mail Whatsapp PDF Image

Background

Coronary CTA images arteries noninvasively without discomfort.

It is used to assess coronary artery disease and detect vascular abnormalities. It has gained prominence for high sensitivity, specificity, and detailed anatomical visualization of coronary vasculature.

Multi-detector CT enhances image resolution and reduces motion artifacts.

CCTA uses contrast-enhanced CT to visualize coronary arteries.

Advantages as follows:

Non-invasive and relatively quick

High negative predictive value

To provide anatomical and functional assessment with perfusion imaging techniques

Multi-detector CT enhances image quality and minimizes motion artifacts.

Advancements in dual-source CT, AI, and reconstruction enhance image quality and diagnostic accuracy.

Modern CT scanners minimize motion artifacts by capturing images quickly. ECG gating synchronizes imaging with cardiac cycle for accuracy.

Post-processing enhances 3D images of coronary vasculature for plaque assessment.

Indications

Assessment of coronary artery disease

Evaluation of chest pain

Preoperative planning

Follow-up of coronary anomalies

Pre-Procedural Planning and Post-Intervention Assessment

Assessment of Cardiac Tumors & Masses

Pericardial Disease

Pulmonary Vein Mapping

Contraindications

Severe Contrast Allergy

Severe Renal Dysfunction

Dialysis patients

Pregnancy

Hemodynamic Instability

High Coronary Artery Calcification

Obesity or Large Body Habitus

Hyperthyroidism

Outcomes

CCTA detects significant coronary artery stenosis with high sensitivity.

Its negative predictive value makes it excellent for ruling out CAD effectively.

Non-obstructive atherosclerosis patients benefit from interventions.

FFR-CT can determine whether a stenosis is hemodynamically significant to reduce unnecessary invasive procedures.

Normal CCTA patients have excellent prognosis, with <1% risk of MI or cardiac death.

Identifies plaque traits linked to acute coronary syndrome.

Equipment required

CT Scanner & Imaging Equipment

Contrast Injection System

ECG Electrodes & Leads

Oxygen & Emergency Kit

Radiation Dose Optimization Tools

Image Processing & Post-Processing Software

Patient Preparation:

Pre-Scan Assessment before scheduling CCTA, assess the patient for indications, contraindications, heart rate, rhythm evaluation, and contrast allergy assessment.

Minimum 4 hours fasting before the scan to reduce motion artifacts from the diaphragm.

Caffeine or smoking should be avoided for 12 to 24 hours before the scan.

During the Scan includes IV Access for contrast injection, ECG monitoring, and breathing instructions

Informed Consent:

Explain the procedure’s risks and potential complications clearly to the patient.

Patient Positioning:

Patient lies flat on back on CT scanner in supine position. Arms above head reduce artifacts and ensure clear field view.

Figure. Coronary CT Angiography

Technique

Step 1: Contrast administration and timing:

Iodinated contrast is injected at 4 to 6 mL/sec using a power injector.

Bolus tracking initiates peak contrast scanning. Saline flush follows contrast to reduce streak artifacts in the superior vena cava.

Biphasic injection protocols prevent streak artifacts from high contrast concentrations in the right heart, using contrast followed by saline. For right heart structure imaging, triphasic protocols with sequential injections are used.

Step 2: Image Acquisition

The initial CCTA image acquisition involves obtaining scout images as low-energy scans using 120 kV tube voltage and 35 mAs.

The ‘test-bolus’ method times contrast enhancement in the ascending aorta at the carina to estimate arrival at coronary arteries.

A CT scanner with 320 detectors enhances cardiac imaging in one rotation, surpassing 64 or 128 detector systems’ capabilities.

ECG-triggered acquisition minimizes exposure by aligning X-ray activation effectively.

Retrospective ECG Gating:

Captures data throughout the cardiac cycle. It shows higher radiation allows functional assessment.

Prospective ECG Gating:

Images acquired only in mid-diastole. Lower radiation exposure but not suitable for irregular heart rhythms.

Complications:

Allergic Reactions to Iodinated Contrast

Contrast-Induced Nephropathy

Contrast Extravasation

Cumulative Radiation Exposure

Arrhythmias

Hypotension from Nitroglycerin

Content loading

Coronary CT Angiography

Updated : April 28, 2025

Mail Whatsapp PDF Image



Coronary CTA images arteries noninvasively without discomfort.

It is used to assess coronary artery disease and detect vascular abnormalities. It has gained prominence for high sensitivity, specificity, and detailed anatomical visualization of coronary vasculature.

Multi-detector CT enhances image resolution and reduces motion artifacts.

CCTA uses contrast-enhanced CT to visualize coronary arteries.

Advantages as follows:

Non-invasive and relatively quick

High negative predictive value

To provide anatomical and functional assessment with perfusion imaging techniques

Multi-detector CT enhances image quality and minimizes motion artifacts.

Advancements in dual-source CT, AI, and reconstruction enhance image quality and diagnostic accuracy.

Modern CT scanners minimize motion artifacts by capturing images quickly. ECG gating synchronizes imaging with cardiac cycle for accuracy.

Post-processing enhances 3D images of coronary vasculature for plaque assessment.

Assessment of coronary artery disease

Evaluation of chest pain

Preoperative planning

Follow-up of coronary anomalies

Pre-Procedural Planning and Post-Intervention Assessment

Assessment of Cardiac Tumors & Masses

Pericardial Disease

Pulmonary Vein Mapping

Severe Contrast Allergy

Severe Renal Dysfunction

Dialysis patients

Pregnancy

Hemodynamic Instability

High Coronary Artery Calcification

Obesity or Large Body Habitus

Hyperthyroidism

CCTA detects significant coronary artery stenosis with high sensitivity.

Its negative predictive value makes it excellent for ruling out CAD effectively.

Non-obstructive atherosclerosis patients benefit from interventions.

FFR-CT can determine whether a stenosis is hemodynamically significant to reduce unnecessary invasive procedures.

Normal CCTA patients have excellent prognosis, with <1% risk of MI or cardiac death.

Identifies plaque traits linked to acute coronary syndrome.

CT Scanner & Imaging Equipment

Contrast Injection System

ECG Electrodes & Leads

Oxygen & Emergency Kit

Radiation Dose Optimization Tools

Image Processing & Post-Processing Software

Patient Preparation:

Pre-Scan Assessment before scheduling CCTA, assess the patient for indications, contraindications, heart rate, rhythm evaluation, and contrast allergy assessment.

Minimum 4 hours fasting before the scan to reduce motion artifacts from the diaphragm.

Caffeine or smoking should be avoided for 12 to 24 hours before the scan.

During the Scan includes IV Access for contrast injection, ECG monitoring, and breathing instructions

Informed Consent:

Explain the procedure’s risks and potential complications clearly to the patient.

Patient Positioning:

Patient lies flat on back on CT scanner in supine position. Arms above head reduce artifacts and ensure clear field view.

Figure. Coronary CT Angiography

Step 1: Contrast administration and timing:

Iodinated contrast is injected at 4 to 6 mL/sec using a power injector.

Bolus tracking initiates peak contrast scanning. Saline flush follows contrast to reduce streak artifacts in the superior vena cava.

Biphasic injection protocols prevent streak artifacts from high contrast concentrations in the right heart, using contrast followed by saline. For right heart structure imaging, triphasic protocols with sequential injections are used.

Step 2: Image Acquisition

The initial CCTA image acquisition involves obtaining scout images as low-energy scans using 120 kV tube voltage and 35 mAs.

The ‘test-bolus’ method times contrast enhancement in the ascending aorta at the carina to estimate arrival at coronary arteries.

A CT scanner with 320 detectors enhances cardiac imaging in one rotation, surpassing 64 or 128 detector systems’ capabilities.

ECG-triggered acquisition minimizes exposure by aligning X-ray activation effectively.

Retrospective ECG Gating:

Captures data throughout the cardiac cycle. It shows higher radiation allows functional assessment.

Prospective ECG Gating:

Images acquired only in mid-diastole. Lower radiation exposure but not suitable for irregular heart rhythms.

Complications:

Allergic Reactions to Iodinated Contrast

Contrast-Induced Nephropathy

Contrast Extravasation

Cumulative Radiation Exposure

Arrhythmias

Hypotension from Nitroglycerin

Free CME credits

Both our subscription plans include Free CME/CPD AMA PRA Category 1 credits.

Digital Certificate PDF

On course completion, you will receive a full-sized presentation quality digital certificate.

medtigo Simulation

A dynamic medical simulation platform designed to train healthcare professionals and students to effectively run code situations through an immersive hands-on experience in a live, interactive 3D environment.

medtigo Points

medtigo points is our unique point redemption system created to award users for interacting on our site. These points can be redeemed for special discounts on the medtigo marketplace as well as towards the membership cost itself.
 
  • Registration with medtigo = 10 points
  • 1 visit to medtigo’s website = 1 point
  • Interacting with medtigo posts (through comments/clinical cases etc.) = 5 points
  • Attempting a game = 1 point
  • Community Forum post/reply = 5 points

    *Redemption of points can occur only through the medtigo marketplace, courses, or simulation system. Money will not be credited to your bank account. 10 points = $1.

All Your Certificates in One Place

When you have your licenses, certificates and CMEs in one place, it's easier to track your career growth. You can easily share these with hospitals as well, using your medtigo app.

Our Certificate Courses