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Anal fissure

Updated : November 29, 2022





Background

A superficial skin tear distal to the dentate border is known as an anal fissure. Anal fissures are frequent in those who have had past anal operations, a history of trauma, a reduced diet with fibers, constipation, and solid stools.

Anal fissures are classified as acute (that can last less than 6 weeks) or chronic (that can last longer than 6 weeks). The anterior or posterior midline is where the bulk of anal fissures are found. To check out alternative reasons, more testing should be done at other places.

This exercise outlines lifestyle changes for preventing the recurrence of anal fissures while describing the causation, clinical characteristics, and types of anal fissures, as well as treatment techniques, including invasive procedures and conservative & postoperative maintenance.

The importance of the interprofessional healthcare professional in treating people with anal fissures and enhancing long-term results is highlighted by this exercise.

Epidemiology

Anal fissures can occur at any age; however, they are more frequently found in children & middle-aged people. Each year throughout the U.S., there are about 250,000 new instances are identified, and both genders are equally impacted.

Anatomy

Pathophysiology

The epithelial portion of the anal canal is referred to as the anoderm. The dentate border is superior to the location. It is a very vulnerable area to microtrauma, and repeated trauma or intense pressure can cause it to rip. Because of the elevated pressures in this region, ischemia-related delayed healing may occur.

Sometimes the tear is severe enough to reveal the sphincter muscle. This causes excruciating discomfort with bowel motions and some rectal blood, along with sphincter spasms. It is well-recognized that the posterior midline, which receives less circulation than the remaining portion of the anal canal, is where anal fissures most frequently occur.

Sphincter tension & anal canal perfusion are mutually exclusive. Other anal fissure locations, including the lateral fissure, are a sign of an underlying cause (ulcerative colitis, Crohn’s disease, HIV, tuberculosis, among others). It is unknown what caused this other site. Rare anterior fissures are linked to dysfunctional and damaged external sphincters.

Etiology

Constipation, tuberculosis, anal tumor, IBD, chronic diarrhea, HIV, STIs, childbirth, past anal surgery, and anal sexual activity are among the important factors of anal fissures. Most acute anal fissures are believed to result from the evacuation of solid stools, STIs, and anal damage from penetration.

Acute anal fissures frequently reoccur, leading to chronic ones. With signs lasting longer than 6 weeks, it is also believed to be brought on by the passage of firm feces against a raised anal sphincter tension pressure.

Both chronic and acute unusual anal fissures can be caused by underlying diseases like TB, bowel disease, anal malignancy, HIV, and previous anal resection. 40 percent of patients who initially have acute anal fissures eventually develop chronic anal fissures.

Genetics

Prognostic Factors

When treated conservatively, acute anal fissures in reduced-risk individuals normally heal within a few days to a week. But a portion of these individuals goes on to acquire CAF, necessitating medication and surgical therapy. Within three to four weeks following surgery, more than 90 percent of patients who need surgical care recover completely.

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

 

nifedipine 

0.2

%

Gels

Topical

every 12 hrs

3 - 6

weeks

20 mg sublingual



Dose Adjustments

Dosing Modifications Hemodialysis (HD) or Peritoneal dialysis (PD):

Supplemental dose not required Cirrhosis: dose adjustment should be considered Administration Should take on empty stomach

 
 

Media Gallary

References

https://www.ncbi.nlm.nih.gov/books/NBK526063/

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Anal fissure

Updated : November 29, 2022




A superficial skin tear distal to the dentate border is known as an anal fissure. Anal fissures are frequent in those who have had past anal operations, a history of trauma, a reduced diet with fibers, constipation, and solid stools.

Anal fissures are classified as acute (that can last less than 6 weeks) or chronic (that can last longer than 6 weeks). The anterior or posterior midline is where the bulk of anal fissures are found. To check out alternative reasons, more testing should be done at other places.

This exercise outlines lifestyle changes for preventing the recurrence of anal fissures while describing the causation, clinical characteristics, and types of anal fissures, as well as treatment techniques, including invasive procedures and conservative & postoperative maintenance.

The importance of the interprofessional healthcare professional in treating people with anal fissures and enhancing long-term results is highlighted by this exercise.

Anal fissures can occur at any age; however, they are more frequently found in children & middle-aged people. Each year throughout the U.S., there are about 250,000 new instances are identified, and both genders are equally impacted.

The epithelial portion of the anal canal is referred to as the anoderm. The dentate border is superior to the location. It is a very vulnerable area to microtrauma, and repeated trauma or intense pressure can cause it to rip. Because of the elevated pressures in this region, ischemia-related delayed healing may occur.

Sometimes the tear is severe enough to reveal the sphincter muscle. This causes excruciating discomfort with bowel motions and some rectal blood, along with sphincter spasms. It is well-recognized that the posterior midline, which receives less circulation than the remaining portion of the anal canal, is where anal fissures most frequently occur.

Sphincter tension & anal canal perfusion are mutually exclusive. Other anal fissure locations, including the lateral fissure, are a sign of an underlying cause (ulcerative colitis, Crohn’s disease, HIV, tuberculosis, among others). It is unknown what caused this other site. Rare anterior fissures are linked to dysfunctional and damaged external sphincters.

Constipation, tuberculosis, anal tumor, IBD, chronic diarrhea, HIV, STIs, childbirth, past anal surgery, and anal sexual activity are among the important factors of anal fissures. Most acute anal fissures are believed to result from the evacuation of solid stools, STIs, and anal damage from penetration.

Acute anal fissures frequently reoccur, leading to chronic ones. With signs lasting longer than 6 weeks, it is also believed to be brought on by the passage of firm feces against a raised anal sphincter tension pressure.

Both chronic and acute unusual anal fissures can be caused by underlying diseases like TB, bowel disease, anal malignancy, HIV, and previous anal resection. 40 percent of patients who initially have acute anal fissures eventually develop chronic anal fissures.

When treated conservatively, acute anal fissures in reduced-risk individuals normally heal within a few days to a week. But a portion of these individuals goes on to acquire CAF, necessitating medication and surgical therapy. Within three to four weeks following surgery, more than 90 percent of patients who need surgical care recover completely.

nifedipine 

0.2

%

Gels

Topical

every 12 hrs

3 - 6

weeks

20 mg sublingual



Dose Adjustments

Dosing Modifications Hemodialysis (HD) or Peritoneal dialysis (PD):

Supplemental dose not required Cirrhosis: dose adjustment should be considered Administration Should take on empty stomach

https://www.ncbi.nlm.nih.gov/books/NBK526063/

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