Dysmenorrhea

Updated: July 16, 2024

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Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

 

valdecoxib

20 - 40

mg

Tablet

Oral

once a day



rofecoxib

50

mg

Orally 

once a day

not more than 5 days



Dose Adjustments

Mild hepatic impairment: 60 mg daily
Moderate hepatic impairment: 30 mg once a day or 60 mg on alternate days

celecoxib

200

mg

Orally 

twice a day



ketoprofen 

Immediate release:

25 - 50

mg

Tablet

Orally 

every 8 hrs



mefenamic acid 

Indicated for Primary Dysmenorrhea:


Initial dose: 500mg orally once then 250mg orally four times a day whenever necessary
Do not exceed for more than three days



mefenamic acid 

Indicated for Primary Dysmenorrhea:


<14 years: Not recommended
>14 years: Initial dose- 500mg orally once, then 250mg orally four times a day whenever necessary
Do not exceed more than three days



calendula 

consume 1 cup tea orally three times a day



diclofenac 

Immediate-release- 100 mg orally once, later 50 mg orally thrice daily as required



pine bark extract 

30 - 60 mg daily



clonidine 

(Off-Label)
Oral administration of 0.025 mg every 12 hours is for two weeks before the start of periods in females:



Dose Adjustments

Not Available

rofecoxib 

Take a dose of 50 mg orally one time in a day for not more than 5 days



dydrogesterone 

10mg to 20mg orally once daily from the 5th to 25th day of the menstrual phase



meclofenamate 

Take a dose of 100 mg orally three times daily for 6 days



flurbiprofen 

50 mg oral tablet 4 times a day



 

meclofenamate 

For <14 years old: Safety and effectiveness not established
For ≥14 years old:
Take a dose of 100 mg orally three time daily for 6 days



 

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References

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Dysmenorrhea

Updated : July 16, 2024
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