Prime Editing Unlocks a Universal Strategy for Restoring Lost Proteins
November 22, 2025
Background
Epidemiology
Anatomy
Pathophysiology
Etiology
Genetics
Prognostic Factors
Clinical History
Physical Examination
Age group
Associated comorbidity
Associated activity
Acuity of presentation
Differential Diagnoses
Laboratory Studies
Imaging Studies
Procedures
Histologic Findings
Staging
Treatment Paradigm
by Stage
by Modality
Chemotherapy
Radiation Therapy
Surgical Interventions
Hormone Therapy
Immunotherapy
Hyperthermia
Photodynamic Therapy
Stem Cell Transplant
Targeted Therapy
Palliative Care
Medication
Mild/Moderate:
500
mg
every 12 hrs or 250 mg every 8hrs
Severe: 875 mg every 12hrs or 500mg every 8hrs
250
mg
Capsule
Orally 
every 6 hrs
500mg orally every 12hrs
250mg orally every 8hrs
25 mg/kg per day in divided doses every 12hrs or 20 mg/kg per day in equal divided doses every 8hrs
Severe: 45 mg/kg per day divided in doses every 12hrs or 40 mg/kg per day in divided doses every 8hrs
25 - 50
mg/kg
Capsule
Orally 
every 8 hrs
(>20kg weight):100mg/kg/day total in equally divided and spaced doses
(<20kg weight): less than 30mg/kg per day in four equally divided and spaced doses
Future Trends
References

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