Irritable Bowel Syndrome

Updated: July 15, 2024

Background

Epidemiology

Anatomy

Pathophysiology

Etiology

Genetics

Prognostic Factors

Clinical History

Physical Examination

Age group

Associated comorbidity

Associated activity

Acuity of presentation

Differential Diagnoses

Laboratory Studies

Imaging Studies

Procedures

Histologic Findings

Staging

Treatment Paradigm

by Stage

by Modality

Chemotherapy

Radiation Therapy

Surgical Interventions

Hormone Therapy

Immunotherapy

Hyperthermia

Photodynamic Therapy

Stem Cell Transplant

Targeted Therapy

Palliative Care

Medication

psyllium

Adults 19-50 years:
For Males 38 g/day, Females 25 g/day, Pregnancy 28 g/day and Lactation 29 g/day
2.5-30 g/day orally in divided doses

dicyclomine

20 mg of dicyclomine is indicated orally every 6 hours
The dose can be increased to 40 mg every 6 hours if efficacy is not attained within 2 weeks
The maximum dose in the case of irritable bowel syndrome is 80 mg per day
For injection dose, 10-20 mg of the intramuscular dose every 6 hours is optimum
Dose consideration
The intramuscular dose should not be used for more than 1-2 days
Replace it with an oral dose as soon as possible
Do not use intravenous dose

linaclotide

Administer 290mcg orally every day

peppermint oil

Administer 0.2ml to 0.4 ml orally thrice a day between the meals

lubiprostone

8 mcg orally 2 times a day

pinaverium

Indicated for Irritable bowel syndrome
50 mg orally three times in a day
It may enhance the dose to 100 mg orally three times in a day if sufficient relief is not reached with the low dosage
It should not exceed the maximum of 300 mg in a day

tenapanor

50 mg orally twice a day before breakfast and dinner

Dose Adjustments

Dosage Modifications
Renal or hepatic impairment: dose adjustment is not required

alverine citrate

60 - 120

Capsules

Orally 

3 times a day

alverine citrate

60 - 120

Capsules

Orally 

3 times a day

Note: this is not recommended for children under the age of 12 years
Indications: this is indicated for use in painful cramps during periods, irritable bowel syndrome, diverticular disease, etc.

Future Trends